Shared Flashcard Set

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Parasitology II lecture
9.7 at 1pm by Dr. Kelly
60
Microbiology
Professional
09/08/2011

Additional Microbiology Flashcards

 


 

Cards

Term
What's the scientific name for pin worm?
Definition
enterobius vermicularis
Term
What's the scientific name for whip worm?
Definition
trichuris trichiura
Term
What's the scientific name for a large roundworm?
Definition
ascaris lumbricoides
Term
What's the scientific name for hookworm?
Definition
necator americanus or ancylostoma duodenale
Term
How many eggs does the female pinworm lay and where does she lay them?
Definition
20,000 eggs perianally
Term
Enterobius vermicularis causes what diseases in the female genital tract?
Definition
vaginitis, granulomatous endometritis or salpingitis
Term
What is the treatment for enterobius vermicularis?
Definition
pyrantel pamoate, mebendazole, and albendazole
Term
How do you prevent enterobius vermiculars infection?
Definition
trim fingernails short, wash hands thoroughly, eggs are sensitive to sunligh, open curtains in daylight
Term
T/F In the case of Enterobius vermicularis infection you treat all family members simultaneously
Definition
true
Term
Where does the female trichuris trichura lay eggs?
Definition
3,000 to 10,000 in the feces daily
Term
How big are adult whipworms?
Definition
30-50mm
Term
How big are adult female pinworms?
Definition
10mm
Term
What are the symptoms of moderate infection of trichuris trichura?
Definition
damage to intestinal mucosa, nausea, abdominal pain, diarrhea, stunted growth
Term
What are the symptoms of heavy infection with trichuris trichura?
Definition
significant mucosal damage, blood loss/anemia and colonic or rectal prolapse
**colonic ulceration may allow bacteria to enter bloodstream which is fatal
Term
How do you diagnose trichurs trichura?
Definition
microscopic identification in stool. Eggs easily visible in symptomatic cases. Also look for eosinophilia.
Term
How do you treat trichuris trichura?
Definition
mebendazole and albendazole
Term
How big are adult ascaris lumbricoides?
Definition
15-40 cm long
Term
How big are adult ascaris lumbricoides?
Definition
15-40 cm long
Term
Describe the size and shape of ascaris lumbricoides eggs?
Definition
elliptical (35 x 55 um) with rough coat
Term
What are the symptoms of heavy ascaris lumbricoides infection?
Definition
fever, wheezing, SOB, abdominal pain, malabsorption of food, intestinal obstruction (due to worm bolus)
Term
Ascaris lumbricoides can migrate to what sites in the body other than intestine?
Definition
appendix, bile duct, or pancreatic duct
Term
What is a sign of ascaris lumbricoides in poorly nourished children?
Definition
growth retardation
Term
T/F Infection with ascaris lumbricoides can result in deaht from respiratory failure.
Definition
true but very rare
Term
Which worm will attempt to exit the body when the patient has a high fever?
Definition
ascaris lumbricoides
Term
HOw do you diagnose ascaris lumbricoides?
Definition
identification of eggs in feces and finding larvae and eosinophils in sputum
Term
How many people in the US are infected with enterobius vermicularis?
Definition
30-40 million
Term
Mebendazole is used for what infections?
Definition
pin, whip, round, tape and hook
Term
Albendazole is used for what infections?
Definition
round, tape and fluke
Term
Adult trichuris trichiura live in the _____.
Definition
cecum (larvae hatch in the small intestine)
Term
What do you use for treatment of ascaris lumbricoides?
Definition
mebendazole and albendazole are preferred if pt also has trichuris trichiura
also, pyrantel pamoate
Term
What do the adult necator americanus look like?
Definition
10mm pinkish-white, hook shaped, 2-14 year lifespan
Term
What does necator americanus feed on?
Definition
worms attach to mucosa of small bowel to suck blood
Term
How many eggs does the necator americanus female release daily?
Definition
10,000-20,000
Term
How big are necator americanus eggs?
Definition
40-60 um
Term
What are the symptoms of necator americanus?
Definition
mostly asymptomatic. "ground itch" on soles of feet for several days, gastric pain, blood loss, eosinophilia in gut and periphery. Pulmonary manifestations similar to ascaris infection; less freqent, less severe
Term
Hypoalbuminemia is comon when you are infected with which helminth?
Definition
necator americanus
Term
Severe anemia caused by necator americanus can cause _______ in children.
Definition
heart failure; also may retard physical/mental/sexual development
Term
Where in the body is the adult necator americanus located?
Definition
mucosa small bowel
Term
Where do ancylostoma duodenale eggs hatch?
Definition
eggs hatch and larvae grow in teh feces/soil
Term
What stage of ancylostoma duodenale is infected?
Definition
third-stage larvae
Term
Where does Ancylostoma infect?
Definition
larvae penetrate skin, carried through blood vessels to heart, then to lungs, coughed up a swallowed. Then mature to adults in small intestine
Term
How do you diagnose ancylostoma duodenale?
Definition
examine stool for worm eggs (may be need to be concentrated) Egg count indicates worm burden and if stool stands for too long eggs may hatch into larvae
Term
The eggs of which two helminths are indistinguishable?
Definition
N. americanus and A. duodenale
Term
How do you treat necator americanus?
Definition
mebendazole, albendazole, and pyrantel pamoate
Term
How do you prevent being infected with necator americanus?
Definition
wearing shoes, practicing good sanitation
Term
How big are adult strongyloides stercoralis?
Definition
2mm
Term
How does strongyloides stercoralis infect its host?
Definition
infective filariform larvae penetrates intact skin initiating infection-->circulatory system--> lungs --> coughed up--> swallowed
Term
How does necator americanus infect host?
Definition
larvae penetrate skin, enter bloodstream, reach heart, lung capillaries, alveolar spaces, are coughed up then swallowed, mature in small intestine
Term
Which worms are coughed up only to be swallowed?
Definition
ascarius lumbricoides, strongyloides stercoralis, ancylostoma duodenale, necator americanus
Term
Where does strongyloides stercoralis lay its eggs?
Definition
gravid female penetrates the mucosa of the duodenum to deposit eggs
Term
What are the two cycles by which strongyloides stercoralis can infect host?
Definition
direct cycle (similar to hookworm) and autoinfective cycle: larvae invade internal mucosa (internal) or peri-anal skin (external)
Term
What are the GI symptoms of strongyloides stercoralis?
Definition
GI- usually asymptomatic, heavy load causes epigastric pain/tenderness made worse by food intake also peptic ulcer-like pain with peripheral eosinophilia. Also, vomiting, diarrhea, malabosprtion may be seen with heavy mucosal damage
Term
What are the pulmonary symptoms of strongyloides stercoralis
Definition
fever/coughing/wheezing/burning in chest/shortness of breath (similar to ascariasis)
Term
What disease has the halmark of peptic ulcer like pain with eosinophilia?
Definition
strongyloides stercoralis
Term
What helminth causes raised red serpinginous (creeping) lesions over buttockes/lower back and why?
Definition
strongyloides stercoralis due to external autoinfection arising from larval invasion of peri-anal area
Term
How do you diagnose strongyloides stercoralis?
Definition
indentify larvae in fresh stool.
if absent from stool, look in duodenal aspirates, jejunal biopsies
Also, can identify larvae in sputum/may culture on agar plates
ELISAs
Term
What is the larva currens?
Definition
a red line on skin that moves (~5cm/day) then disappears when you become infected with strongyloides stercoralis
Term
What is the treatment for strongyloides stercoralis?
Definition
ivermectin and thiabendazole
Term
How do you prevent strongyloides stercoralis infection?
Definition
good sanitation, avoid fecal contamination of water/soil/food
Term
What type of drug is ivermectin?
Definition
broad spectrum anti-parasitic
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