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Parasitology Exam III (UW Madison Path350)
Arboviruses, Hookworms, Whipworms, class Arthropoda
160
Pathology
Undergraduate 3
05/15/2012

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Term
This disease can go from sylvatic to urban but NOT urban to sylvatic
Definition
Yersinia pestis
Term
A young patient is shorter than she should be for her age and has clubbing of her fingers. What parasite might she have?
Definition
Trichuris trichiura
Term
About 800 million people are infected with this parasite worldwide
Definition
Trichuris trichiura
Term
The egg of this parasite takes 21 days to embryonate
Definition
Trichuris trichiura
Term
How do you diagnose if an individual has Trichuris trichiura? What drug might treat this parasite?
Definition
Fecal examination looking for eggs

Albendazole
Term
Why did the elite have higher incidences of Yersinia pestis than the peasants in the mid-1300s?
Definition
The elite had enough money to eat lots of meat and the Yersinia pestis bacteria (black death) loves iron. The peasants rarely had access to such foods.
Term
This is the parasite that transmits trench fever
Definition
Pediculus humanus humanus
Term
This parasite attaches its eggs to the clothing of an individual
Definition
Pediculus humanus humanus
Term
The principle host of this pathogen is birds
Definition
West Nile virus
Term
The vector for this is the culex mosquito and there is no treatment for this zoonotic pathogen
Definition
West Nile virus
Term
The principle host for this pathogen is the chipmunk
Definition
LaCrosse Encephalitis
Term
The vector for this pathogen is Aedes triseriatus
Definition
LaCrosse Encephalitis
Term
This parasite attaches to pubic hair
Definition
Phthirus pubis
Term
This parasite is transmitted by sexual contact but does not transmit any diseases
Definition
Phthirus pubis
Term
This vector for this parasite is mansonia crassipes
Definition
Brugia malayi
Term
This parasite is found in SE Asia and while its primary host is humans, cats and monkeys can be reservoir hosts
Definition
Brugia malayi
Term
This is the bacteria responsible for lyme disease
Definition
Borrelia burgdorferi
Term
This vector for this pathogen is Ixodes scapularis
Definition
Borrelia burgdorferi
Term
You have a patient presenting with a fever and a bullseye lesion on their right leg. What pathogen might they have?
Definition
Borrelia burgdorferi
Term
Your daughter comes home from school with a scratchy scalp and upon further investigation you spot nits attached to her hair. What does she have? Do you have to worry about it transmitting any diseases?
Definition
Pediculus humanus capitis

No
Term
The vector for this parasite is Aedes trivittatus
Definition
Dirofilaria immitis
Term
This parasite infects the malpighian tubules of its mosquito vector
Definition
Dirofilaria immitis
Term
Your dog starts having respiratory problems and is showing signs of ascites. What might he have?
Definition
Dirofilaria immitis
Term
Dog heart worm
How you you prevent it?
Definition
Dirofilaria immitis
DEC daily or Ivermectin once a month
Term
This life cycle of this parasite has a sausage stage
Definition
Dirofilaria immitis
Term
The vector for this pathogen is Aedes aegypti
Definition
Dengue fever
Term
This virus is strictly a human virus
Definition
Dengue fever
Term
When infected with what pathogen should you not take Aspirin? Why?
Definition
Dengue fever
it's a blood thinner
Term
This vector for this pathogen is Xenopsylla cheopis
Definition
Yersinia pestis
Term
What species does Xenopsylla cheopis feed on normally? Why does it jump to humans?
Definition
Rattus rattus and Rattus norvegicus
Jump to humans because Yersinia pestis kills all of the rats and humans are the next closest blood meal
Term
The parasite that transmits Borrelia bergdorferi
Definition
Ixodes scapularis
Term
This mosquito lays its eggs in a raft conformation
Definition
Culex (house mosquito)
Term
This mosquito lays its eggs on the water edge
Definition
Aedes (flood water mosquito)
Term
This mosquito lays one egg at a time on the water surface
Definition
Anopheles (dappled winged mosquito)
Term
The larvae of this mosquito lays flat on the water surface
Definition
Anopheles (dappled winged mosquito)
Term
The condition where a tick is in your ear canal
Definition
otocariasis
Term
Family that includes the hard ticks
Definition
Ixodidae
Term
This parasite can infect pups still in the uterus in dogs
Definition
Toxocara canis
Term
This parasite is also called the "new world" hookworm. It has a cutting plate.
Definition
Necator americanus
(similar to Ancylostoma duodenale)
Term
This parasite infects dogs and has 2 pairs of 3 teeth
Definition
Ancylostoma caninium
(similar to Ancylostoma duodenale)
Term
This parasite is also called the "old world" hookworm. It has 2 teeth.
Definition
Ancylostoma duodenale
Term
How do you diagnose Ancylostoma duodenale?
Definition
Fecal examination looking for eggs
Term
The common name for this parasite is the pinworm
Definition
Enterobius vermicularis
Term
You've noticed that your son has been itching his butt a lot recently. What parasite might he have?
Definition
Enterobius vermicularis
Term
This parasite can be transmitted through a hand-to-mouth cycle, inhaling eggs, or autoinfection.
Definition
Enterobius vermicularis
Term
The egg of this parasite is particularly fragile. Controlled heating helps its prevalence in homes.
Definition
Enterobius vermicularis
Term
What is the order and family in which the mosquito belongs?
Definition
Order diptera
Family culicidae
Term
The condition caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori
Definition
Lymphatic filariasis
Term
The diagnosis for this condition used to involve bleeding at night to look for microfilari, now they use antigen detection kits.
Definition
Lymphatic filariasis from W. bancrofti, B. malayi, and B. timori
Term
The main symptoms of this pathogen are lymphedema and secondary infections
Definition
Lymphatic filariasis
Term
the common bed bug
Definition
Cimex lectularis
Term
This parasite infects humans in addition to bats and chickens and transmits no diseases
Definition
Cimex lectularis
Term
What is the order and family of Cimex lectularis
Definition
Order Hemiptera
Family cimicidae
Term
This parasite can only be transmitted if the principle host (rodent) is eaten
Definition
Capillaria hepatica
Term
This parasite lives in the liver of rodents
Definition
Capillaria hepatica
Term
The vector for this parasite is Culex pipiens, Anopheles gambiae, or Aedes polynesiensis
Definition
Wuchereria bancrofti
Term
This parasite affects people living in Africa, S. America, and Oceana and is responsible for 90% of the world's cases of lymphatic filariasis
Definition
Wuchereria bancrofti
Term
The infective stage is called the cystacanth
Definition
Phylum Acanthocephala
Term
The males in this group plug the females with "cement" after mating
Definition
Phylum Acanthocephala
Term
This parasite affects water fowl and fish
Definition
Phylum Acanthocephala
Term
The thorny headed worms
Definition
Phylum Acanthocephala
Term
Your children play in the sandbox in your backyard often and have recently began get red squiggly rashes on their legs. Your doctor asks if there are any cats in your neighborhood. What parasite does the doctor think your children has? What condition have they developed?
Definition
Ancylostoma braziliense
cutaneous larva migrans
Term
What four parasites can cause visceral larva migrans in humans?
Definition
Toxocara canis
Baylisascaris
Toxocara cati
Ascaris suum
Term
What parasites can cause cutaneous visceral migrans in humans?
Definition
Ancylostoma braziliense (most common)
Ancylostoma caninium
Term
The only way to diagnose this parasite is with a muscle biopsy.
Definition
Trichinella spiralis
Term
What parasite institutes nurse cells in muscles?
Definition
Trichinella spiralis
Term
The male parasites of this infection are excreted in the feces while the females remain in the intestine to produce eggs.
Definition
Trichinella spiralis
Term
What whipworm can humans get from eating raw pork? Can we transmit the parasites to anyone else? Why or why not?
Definition
Trichinella spiralis
No- can only be transmitted by eating an infected animal, humans aren't normally eaten
Term
The fleas belong in what order?
Definition
Siphonaptera
Term
This order of parasites are laterally compressed and both the males and the females blood feed.
Definition
Siphonaptera
Term
The larva of these parasites do not blood feed, but instead eat anything organic
Definition
Siphonaptera
Term
Causes river blindness
Definition
Onchocerca volvulus
Term
The vector for this parasite is simulium
Definition
Onchocerca volvulus
Term
The only way to diagnose this parasite is to do a skin snip looking for microfilari
Definition
Onchocerca volvulus
Term
You have one patient from Latin America with a nodule on his head and another patient from Africa with a nodule on his leg. You suspect the same parasite for both, what is it?
Definition
Onchocerca volvulus
Term
The symptoms of this parasite are nodules under the skin, elephant skin, and massive secondary infections. What parasite is it?
Definition
Onchocerca volvulus
Term
A hookworm of cats that cannot infect kittens in-utero
Definition
Toxocara cati
Term
giant kidney worm
Definition
Dioctophyme renale
Term
This parasite uses aquatic worms as its intermediate host and anything that eats fish as a principle host
Definition
Dioctophyme renale
Term
The eggs of the parasite are passed in the urine
Definition
Dioctophyme renale
Term
You are performing a necropsy on a dog that died mysteriously. Upon kidney inspection you see a clump bright red whip worms only surrounding the right kidney. What parasite is this?
Definition
Dioctophyme renale
Term
This parasite can either be parasitic or free living
Definition
Strongyloides stercorals
Term
The females of the parasite do not require sperm to reproduce
Definition
Strongyoides stercorals
Term
This parasite infects humans, primates, dogs, and cats. Sometimes you can get a deseminated infection and get severe bacterial infections.
Definition
Strongyloides stercorals
Term
How do you diagnose Strongyloides stercorals?
Definition
cannot use a sugar solution like looking for eggs (this parasite releases L1 into the feces) so you MUST do a fecal smear
Term
This is the most common flea in the world
Definition
Ctenocephalides felis
Term
guinea worm
Definition
Drancunculus medinensis
Term
You have a patient that has large blisters on her legs and you advise her not to go into any water. What parasite is it and why did you advise that?
Definition
Drancunculus medinensis
The blisters will burst in water and female worm will release millions of larvae
Term
This parasite uses cyclops as an intermediate host
Definition
Drancunculus medinensis
Term
How do you treat drancunculus medinensis?
Definition
Removal of the female worm from blisters
Term
This is a tick of dogs
Definition
Dermacentor variabilis
Term
This parasite transmits rocky mountain spotted fever
Definition
Dermacentor variabilis
Term
Anautogenous
Definition
Mosquitoes that need a blood meal before can lay eggs (most)
Term
Mosquitoes that need a blood meal before can lay eggs
Definition
anautogenous
Term
Autogenous
Definition
Mosquitoes that do not need a blood meal before can lay eggs (few)
Term
Mosquitoes that do not need a blood meal before can lay eggs
Definition
Autogenous
Term
Ornithophilic
Definition
Mosquitoes that feed on birds
Term
Mosquitoes that feed on birds
Definition
Ornithophilic
Term
Zoophilic/mammalophilic
Definition
Mosquitoes that feed on mammals
Term
mosquitoes that feed on mammals
Definition
zoophilic
mammalophilic
Term
Anthropophilic
Definition
Mosquitoes that feed on humans
Term
Mosquitoes that feed on humans
Definition
Anthropophilic
Term
Endophagic
Definition
Mosquitoes that feed indoors (Anopheles gambiae)
Term
Mosquitoes that feed indoors (Anopheles gambiae as an example)
Definition
Endophagic
Term
Exophagic
Definition
Mosquitoes that feed outdoors
Term
Mosquitoes that feed outdoors
Definition
Exophagic
Term
Cresuscular
Definition
Mosquitoes that feed at dusk/dawn
Term
Mosquitoes that feed at dusk/dawn
Definition
Cresuscular
Term
Nocturnal
Definition
Mosquitoes that feed at night
Term
Mosquitoes that feed at night
Definition
Nocturnal
Term
Three types of Yersinia pestis
Definition
bubonic plague- in lymphocytes
Septicemic plague- in blood system
Pneumonic plague- in lungs
Term
Diagnosis and treatment of yersinia pestis
Definition
Diagnosis: antigen assay
Treatment: antibiotics
Term
Life cycle of Trichuris trichiura
Definition
adult in large intestine of human-->eggs go out in the feces-->eggs embryonate-->human ingests eggs
Term
Describe the eggs of Trichuris trichiura
Definition
Takes 21 days to embryonate
extremely fragile
Term
Symptoms associated with Trichuris trichiura
Definition
anemia, mental/physical growth retardation, diarrhea, finger clubbing, rectal prolapse
Term
name the three pathogens that can be transmitted by pediculus humanus humanus
Definition
Trench fever, louse borne typhus, louse borne relapsing fever
Term
How is the bacteria that causes trench fever transmitted?
Definition
Pediculus humanus humanus leaves feces on the skin and the host scratches it into their skin. Bacteria is in feces.
Term
What is the vector for West nile virus?
Definition
Culex
Term
What is the vector for LaCrosse encephalitis?
Definition
Aedes triseriatus (tree hole mosquito)
Term
What is the principle host for LaCrosse encephalitis?
Definition
Chipmunks
Term
What are three ways LaCrosse encephalitis can be transmitted between mosquitoes?
Definition
1. Transovarial
2. Transstadial
3. male mosquitoes infect female mosquitoes
Term
What is the vector for Brugia malayi?
Definition
Mansoni
Term
What is the vector for Borrelia burgdorferi?
Definition
Ixodes scapularis
Term
How is Borrelia burgdorferi transmitted?
Definition
NO transovarial transmission
Nymphs pass it to humans (adults stick to mice)
Term
Symptoms associated with borrelia burgdorferi
Definition
bullseye lesion, fever, inflammation at bite, joint pain...
Term
What is order Anoplura
Definition
sucking lice
Term
Life cycle of Dirofilaria immitis
Definition
adult worms in heart of dog, adults produce microfilari (mf), mf circulate in blood, mosquito bites, from gut of mosquito migrate to malpighian tubules (kidneys), go to distal end and penetrate cells, develop into L1 (sausage stage), develop into L2 (gain mouth parts), in 12 days develop into L3, L3 break out of cell and migrate to mouthparts, mosquito bites a dog, L3 gets in subcutaneous tissue, develops to L4, L4 migrates to heart, doesn't develop into adult for 6 months
Term
Pathology associated with Dirofilaria immitis
Definition
respiratory problems, ascites (fluid build up)
Term
What is the vector for Dirofilaria immitis?
Definition
Aedes trivittatus
Term
What is the vector for Dengue fever?
Definition
Aedes aegypti
Term
What is the vector for Yersinia pestis?
Definition
Xenopsylla cheopis (oriental rat flea)
Term
What is the transmission route for yersinia pestis?
Definition
Flea takes a blood meal from an infected rat, bacteria replicates in the gut, build up of bacteria blocks digestive tract and causes the flea to go for another blood meal, when take blood meal tract is blocked so vomits back blood and bacteria along with it
Term
Life cycle of Enterobius vermicularis
Definition
female lays eggs in posterior end of the gut or can crawl out of anus and lay eggs on the perinium, host scratches, puts hand in mouth (hand-to-mouth cycle)
Term
Life cycle of mosquitoes
Definition
females lay eggs in water, eggs hatch (larvae called wigglers), 3 molts, 4 instars, 4th instar pupates into pupa (called tumbler), develop into adult, gets blood meal after 2/3 days
Term
Life cycle of parasites that cause Lymphatic filariasis
Definition
adults in lymphatics of human, worms mate, adults produce microfilari (mf), mf migrate to lymph then to the blood, mosquito bites, mf penetrate gut of mosquito, mf migrate to thoracic muscles of mosquito, mf molt L1, L2, L3, L3 migrates to proboscis, mosquito bites human
Term
How do you diagnose Lymphatic filariasis?
Definition
Old method: bleed at night and look for microfilari
New method: antigen based detection kits looking for antibodies
Term
Life cycle of capillaria hepatica
Definition
adult worm in parenchyma of rodent liver, rodent eaten by carnivore, eggs passed in the feces of carnivore, rats eat feces
Term
Sexual dimorphism in Wuchereria bancrofti
Definition
females: long and slender with round ends
males: short with curved end
Term
What is the vector for Wuchereria bancrofti?
Definition
Culex pipiens, Anopheles gambiae, Aedes polynesiensis
Term
Life cycle of parasites in the order Ancanthocephala
Definition
Adults in the definitive host, eggs out in the feces, eggs ingested by arthropods, ancanthor develops in egg, ancanthor breaks out of gut into the body cavity, develop into ancanthella (feeding stage), develop into cystacanth (infective stage), arthropod eaten by definitive host (ducks, fish)
Term
What is the vector for Loa loa?
Definition
Tabanids (deer fly)
Term
How do you treat Loa loa?
Definition
NO DEC! surgical removal of worms
Term
Life cycle of Ancylostoma duodenale
Definition
adults produce eggs in gut, eggs out in feces, hatch and develop into L1, L2, L3, L3 penetrate skin of definitive host, L3 goes through blood to the heart, goes to the lungs, gets coughed up, swallowed, and develops into an adult in the intestine
Term
Life cycle of Trichinella spiralis
Definition
human eats raw pig (larvae in muscle), larvae encyst in intestinal villi, worms mate, males go out in feces, females produce life larvae which go into the blood, larvae distribute to any muscle (prefer jaw, eye, diaphragm), larvae get into muscle cells and take over (nurse cells), nurse cell eaten
Term
How do you diagnose Trichinella spiralis?
Definition
muscle biopsy
Term
Name 6 characteristics of siphonaptera
Definition
1. they are ectoparasites
2. they are laterally compressed
3. both male and females blood feed
4. larvae do not blood feed but will eat anything organic
5. eggs develop off the host
6. larvae only emerge when detect host near (CO2 levels)
Term
What is the vector for Onchocerca volvulus?
Definition
Simuliidae simulium (black fly)
Term
What is the life cycle of Onchocerca volvulus?
Definition
adults in nodules under the skin, they produce microfilari (mf), mf crawl around under the skin, black fly bites, mf go to gut of black fly, molt L1, L2, L3, L3 migrates to mouth parts, black fly bites human
Term
How do you diagnose Onchocerca volvulus?
Definition
Skin snip looking for microfilari
Term
What is the pathology associated with Onchocerca volvulus?
Definition
secondary infections, loss of skin elasticity, tissue discoloration, elephant skin
Term
What disease does Onchocerca volvulus cause?
Definition
River blindness
Term
Life cycle of Ascaris lumbricoides
Definition
adults in the gut, produce eggs, eggs out in feces, eggs embryonate, definitive host eats the eggs, larvae penetrate the intestinal wall, larvae get into hepatic system, go to lungs, molt a few times, get coughed up, swallowed, back to gut, develop into adult
Term
Life cycle of Dioctophme renale
Definition
eggs pass in urine and HAVE to get into water, eggs eaten by aquatic worms, larvae develop in aquatic worm and become infective, fish eats worms, fish eaten by definitive host
Term
Life cycle of Strongyloides stercorals
Definition
adults in intestine, produce eggs, eggs hatch IN intestine, L1 go out in feces, from here can go one of two ways: 1. L1 can develop to L2, L3, L4, adult (cycle starts over IN SOIL) or 2. L1 can develop to L2, L3, L3 can penetrate skin of human, go into blood, to the heart, to the lungs, get coughed up, swallowed, back to the gut, develop into adult
Term
How does the life cycle of Strongyloides stercorals differ if it's in an immuno-incompetent host?
Definition
Larvae in intestine never leave in feces and mold 2x to become L3 (autoinfection)
Term
What happens if Stronyloides stercorals gets out of intestine?
Definition
Larvae can migrate out of intestine to other tissues and bring bacteria from the gut with them (massive bacterial infections- can be fatal)
Term
How do you diagnose Strongyloides stercorals?
Definition
fecal SMEAR looking for L1
Term
what is the common name of Drancunculus medinensis?
Definition
guinea worm
Term
What is the life cycle of Drancunculus medinensis?
Definition
adults in legs of host right under the skin, larvae build up in the uterus of the female worm, causes massive allergic reaction and forms blister, host goes into the water, blister burst, females release millions of larvae, larvae eaten by cyclops copopod, human drinks the water
Term
How do you treat Drancunculus medinensis?
Definition
remove female from blister
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