Term
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Definition
| Does not require prior exposure to specific substance |
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Term
|
Definition
| Requires prior exposure to a specific substance |
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Term
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Definition
| Physical barriers of the host |
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Term
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Definition
| Innate, nonspecific defenses of host |
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Term
|
Definition
| Specific and acquired (immune system) |
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Term
| Types of white blood cells |
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Definition
Neutrophils
Monocytes / Macrophages
Eosinophils
Lymphocytes
Natural killer cells
Basophils |
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Term
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Definition
Professional phagocyte
Kamakazi cells
First on scene
Non-specific action
Non-dividing
Granules contain hydrolytic enzymes |
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Term
|
Definition
Professional phagocyte
Killers and scavengers
Clean up crew
Long lived
Will divide at site |
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Term
|
Definition
Cytotoxic cell
Granules that are toxic and hydrolytic
Anti-parasitic activity
Allergic response |
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Term
|
Definition
Non-specific
Cytotoxic
Defense against tumor cells and infected cells |
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Term
|
Definition
Non-specific response
Triggered by tissue damage
Initiated by cytokines released by injury cells and white blood cells
Signs: redness, heat, swelling, pain |
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Term
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Definition
| Any pathological change in tissue |
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Term
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Definition
| Development of abnormal conditions and the structural and functional changes that result from the disease process |
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Term
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Definition
| Pus: dead neutrophils, dead tissue, extravascular fluid |
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Term
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Definition
Pus-filled cavity
Lesion created by the inflammatory process |
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Term
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Definition
| Lesion open to the surface |
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Term
|
Definition
Accumulation of inflammatory cells, especially macrophages, around inflammatory causative agent
Accumulation becomes walled off by fibrous connective tissue isolating the causative agent |
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Term
|
Definition
Any foreign molecule that elicits a specific immune response
Initiator and driving force of immune system |
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Term
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Definition
| Proteins secreted by B cells in response to a specific antigen |
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Term
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Definition
Antibody producers
Stay in bone marrow |
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Term
|
Definition
Include two major types: cytotoxic (defenders / killers) and helpers (facilitators)
Migrate to thymus |
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Term
|
Definition
| Removal of all immune cells with receptors capable of reacting with self components |
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Term
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Definition
| Programmed cell death through activation of proteases and nucleases |
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Term
| Major Histocompatibility Complex |
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Definition
Found on cell membranes
Protein self markers that serve as a biochemical fingerprint
Antigen presenters to T lymphocytes
Not antigen specific |
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Term
|
Definition
| Found on all nucleated cells |
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Term
|
Definition
| Found on specialized cells such as B cells, Helper T cells, Macrophages, and Thymus cells |
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Term
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Definition
Cytotoxic T cells are effector cells
Go after intracellular pathogens |
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Term
| Humoral Immunity (Antibody Mediated Immunity) |
|
Definition
B Cells are effector cells
Go after extracellular pathogens |
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Term
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Definition
| Contain MCH I receptor: CD8 |
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Term
|
Definition
| Contain MCH II receptors (CD4) |
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Term
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Definition
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Term
|
Definition
| Anamnestic (secondary) response antibody |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
Low percentage in circulation but always some present and attached to basophils and mast cells
Hight levels indicate parasites and allergies |
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Term
|
Definition
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Term
|
Definition
Activate cell-mediated immunity
Can suppress humoral immunity |
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Term
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Definition
Activate humoral immunity
Can suppress cell-mediated immunity |
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Term
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Definition
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Term
|
Definition
| Phagocytosis induced by binding of antibody |
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Term
|
Definition
Immune response involved
Time to develop with first contact
Memory
Naturally acquired
Vaccines |
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Term
|
Definition
Pre-formed (anti-venom)
Immune response not involved
Immediate protection
No memory
Administer each time
Natural (breast milk, placenta) |
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