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Parasites Review
ID exam #3
64
Medical
Graduate
03/25/2011

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Term

The most common parasitic infections in the US include Trichmoniasis, Cryptosporidium, Toxoplasmosis and ___________

Definition
Giardiasis
Term
Neglected Tropical Diseases (NTDs) kill approximately 2 million people every year worldwide, the mots deadly of these NTD's is
Definition
Malaria
Term
We are observing an increase in the frequency of parasitic infections in the US thought to be due to increase in travel, military deployment, humanitarian missions and inflow of immigrants and the increased prevalence of
Definition
Immunocompromised patients
Term
Food, fluids, fingers, feces and money are all examples of ____________ which are substances capable of absorbing and transmitting agents of disease
Definition
Fomites
Term
Does not cause parasitic infections, but is often necessary to transmit the causative parasite to the host
Definition
Vector
Term
Lice, bedbugs, chiggers and leeches are all examples of
Definition
Ectoparasites
Term
Mosquitoes, reduviid bugs, sandflies and leeches are all what type of organism
Definition
Hematophagus
Term
Lindane (Kwell), permethrin, pyrethrin and ____________ are good topical treatment options for treating pediculus humanus capitis (head lice)
Definition
Malathion
Term
Eggs of the lice which are cemented into hairshafts of the host by the gravid head louse are called
Definition
Nits
Term
Headlice are a common problem for ___________ because they share hats, hair ornaments and napping pads
Definition
Young children
Term
Headlice are a common problem for ___________ because they share hats, hair ornaments and napping pads.
Definition
Young children
Term
Entamebe histolytica, gairdia lamblia, leishamania, trichomonas and plasmodium ovale are all examples of what parasite
Definition
Flagellated
Term
When treating trichomoniasis, it is important to treat the patient as well as
Definition
all sex partners
Term
When treating a patient complaining of foul smelling urethral discharge, painful itchy urination, and demonstates flagellated protozoa in the urine 4-28 days after intercourse, what is the treatment
Definition
Metronidazole, 2G x1 dose
Term
Malaria is caused by __________ which is transmitted by ______________.
Definition
Plasmodium, Infection female Asnopheles mosquito
Term
The hallmark classic s/sx of an active malaria infection include anemia, fever, HA, chills and ____________
Definition
Rigors
Term
When diagnosing malaria, we often consider the patient's travel history, clinical s/sx, exposure to mosquitoes or blood, and lab analyses. In field screening that may be used is
Definition
Parasight dipstick test
Term
When diagnosing malaria, we often consider the patient's travel history, clinical s/sx, exposure to mosquitoes or blood, and lab analyses. In field screening that may be used is
Definition
Parasight dipstick test
Term
Four most common species of plasmodium
Definition
Falciparum, Malariae, Vivax, Ovale
Term
Plasmodium species with highest degree of chloroquine resistance is
Definition
Falciparum
Term
The plasmodium organism replicates asexually and sexually; replicates in the mosquitoes gut, host's RBC's and
Definition
Host's liver
Term
The cause of anemia, rigors and splenomegaly in humans with malaria infestations is the result of
Definition
Erythrocyte hemolysis
Term
Alternates to Chloroquine for prophylaxis for travel to areas endemic for malaria
Definition
hydroxychloroquine, metfloquine
Term
All px medications for malaria require initiation prior to travel and continuation throughout and upon return for an additional four weeks except
Definition
Malarone
Term
When prophylaxing against malaria in areas suspected but not documented resistance to chloroquine the traveler should
Definition
Add proquanil beginning the LAST 2 weeks for chloroquine px.
Term
Non-pharmacological approaches to malaria prevention
Definition
Avoid areas, sleep under nets, clear standing water, apply DEET to clothes,linens and skin
Term
Mefloquine can be used for px and treatment of malaria. What is the dose
Definition
5X the prophylaxis dose give during loading dose of quinine/quinadine
Term
Drug used for treatment of severe malaria that is the aqueously soluble enantiomer of Quinine
Definition
Quinidine gluconate
Term
Tonic water originally from peruvian cinchona bark and contained
Definition
quinidine
Term
Sweet wormwood has been shown to provide active antimalarial extracts one of which is _____________
Definition
Artemisin, which is becoming an alternative treatment of malaria
Term
When traveling through chloroquine resistant areas, pregnant women should px with
Definition
Mefloquine or Azithromycin
Term
When traveling through chloroquine resistant areas, pregnant women should px with
Definition
Mefloquine or Azithromycin
Term
When traveling through chloroquine resistant areas, pregnant women should px with
Definition
Mefloquine or Azithromycin
Term
Total accumulative dose of chloroquine phosphate for a two week trip to an endemic area
Definition
3500mg
Term
Quinine drug specific side effects
Definition
nausea, fever, vertigo
Term
Metfloquine specific side effects
Definition
heart palpitations, vivid dreams, insomnia
Term
Species of Entameoba that can invade tissues and cause liver abscess
Definition
Entameoba Hystolica
Term
Entameoba hystolica best treated with
Definition
dihydroemetine, chloroquine or metronidazole (all are tissue active)
Term
Entameoba Dispar is best treated with
Definition
Iodoquinol, diloxanide or paramomycin. (all luminal amebocides)
Term
Asymptomatic cyst passers of Entameoba are usually treated with
Definition
Luminal amebicides (Iodoquinol, diloxanide, or paramomycin.
Term
amebiasis and giardiasis are protozoal infestations associated with severe diarrhea and are transmitted by
Definition
drinking fecal contaminated water
Term
Person to person transmission of giardia
Definition
sharing tubs, pools, ponds, toys and through oral-anal contacts
Term
Test used for diagnosis of giardiasis
Definition
Entero Spring test
Term
Test used for diagnosis of giardiasis
Definition
Entero Spring test
Term
Giardiasis symtpoms
Definition
severe diarrhea, cramping, exudates in stool, flatulence
Term
Giardiasis treatment
Definition
Metronidazole for 5-7 days
or
Tinidazole 2G PO x1
Term
DOC for pregnant women with giardiasis or amebiasis
Definition
Paromycin
Term
Dum-dum fever, Kala-azar, black fever or Assam fever are all colloquial names for
Definition
visceral form of Leshmaniasis
Term
Mucocutaneous form of Leishmaniasis can mutilate the mucosa of
Definition
Nose / Soft palate and trachea
Term
Leishmaniasis incubation period
Definition
10 days to 2 years
Term
Leishmaniasis most commonly transmitted via
Definition
Sandflies bites.
Term
common intermediary hosts (reservoirs) for leishmaniasis (sandflies)
Definition
Dogs, foxes, squirrels, rodents
Term
treatment of leishmaniasis
Definition
parenteral Amphotericin B
Pentamidine
*Stibolgluconate 20-28 days CIVI
Term
African sleeping sickness and chagas disease both caused by what protozoan species
Definition
Trypanosomiasis
Term
Two major forms of trypanosomiasis and their parasites
Definition
African sleeping sickness - tse-tse fly
Chagas disease - ruduviid bug
Term
Romana's sign
Definition
aka chagoma; seen in children infected by trypanosomiasis resulting from rubbing eyes with feces of vector
Term
trypanosomiasis treatment
Definition
nitroburtimox (Lampit) x4mos or
benidazole (Rochagon) x3mos
Term
Treatment of ringworm (most common helminth infestation in US) and tapeworm
Definition
pyrantel pamoate (Antiminth)
Term
Albendazole characterstics
Definition
Can be effective with one dose, but best absorbed when taken with a high fat meal.
Term
Hookworm treatment
Definition
Mebendazole 100mg PO x3d
Term
Hookworm characteristics
Definition
penetrates skin of victim, once inside of host's tissues migrates to small intestine where it can be liberated to infect another host.
Term
Pinworms are spread and populated in the host by
Definition
autocaprophagic means
Term
dracunculus medenisis not treatable by medication. Best prevented by
Definition
purifying drinking water or treated through manual removal.
Term
Wucheria bancrofti is a filarial worm that causes
Definition
Elephantitis by migrating into the lymphatic system causing obstruction and edema of the effected extremity
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