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Paramedics Emergency Med
List of Emergency meds action, class, indications, adverse effects, contraindictations, dosage, pediatric and adult, special considerations.
69
Pharmacology
Professional
09/26/2014

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Term
Ipratropium Bromide Trade name
Definition
Atrovent
Term
Ipratropium Bromide Class
Definition
Bronchodilator, anticholinergic
Term
Atrovent action
Definition
antagonizes the ACH receptor on bronchial smooth muscle, producing bronchodilation
Term
Atrovent Indications
Definition
Asthma Bronchospasm associated with COPD
Term
Ipratropium Bromide Side Effects
Definition
Paradoxical acute Bronchospasm, cough, throat irritation, headache, dizziness, dry mouth, palpiations
Term
Ipratropium Bromide Contraindications
Definition
Closed angle glaucoma, bladder neck obstruction, prostatic hypertrophy, known sensitivty to peanuts or soy beans and atropine or atropine derivatives
Term
Atrovent Dosage Adult
Definition
.5 mg every 6-8 hours
Term
Atrovent Dosage Pediatric
Definition
5-14 years .25 mg to .5 mg every 20 min for 3 doses as needed
Term
Special Considerations Atrovent
Definition
Atrovent is not typically used as sole medication in treatment of acute exacerbation of asthma. Commonly used after beta agonist.
Not to come in contact with eyes
Pregnancy class B
Term
Albuterol Trade Name
Definition
ProAir Ventolin
Term
Albuterol Classification
Definition
Beta 2 agonist Bronchodilator
Term
Albuterol Action
Definition
Binds and stimulates beta 2 receptors, resulting in relaxation of bronchial smooth muscle
Term
Albuterol Indications
Definition
Asthma, Bronchitis with bronchospasm and COPD
Term
Albuterol Adverse Effects
Definition
Hyperglycemia, hypokalemia, palpitations, sinus tachycardia, anxiety, tremor, nausea/vomiting, throat irritation, dry mouth hypertension, dyspepsia, insomnia, headache, episataxis paradoxical Bronchospasms
Term
Albuterol Contraindications
Definition
Angiodema sensitivity to albuterol or levalbuterol. Lactating patients cardiovascular disorders cardiac arrhythmias
Term
Albuterol Dosage Adult
Definition
2.5 to 5mg every 20 min for mnaximum 3 doses. After initial 3 doses escalate the dose or start a continuous nebulization at 10 to 15 mg/hr
Term
Albuterol Dosage Pediatric
Definition
>12 years continuous nebulizer.5mg/kg/hr
<12 .15mg/kg every 20 min for max 3 doses. Alternatively continuous nebulization at .5mg/kg/hr can be delivered to children younger than 12 years
Term
Albuterol Special Considerations
Definition
Pregnancy class C
Term
Succinylcholine
Trade name
Definition
Anectine
Term
Succinylcholine
Classification
Definition
Neuromuscular blocker, depolarizing
Term
Succinylcholine
Action
Definition
Competes with the acetylcholine receptor of the motor end plate on the muscle cell, resulting in muscle paralysis
Term
Succinylcholine
Indications
Definition
To induce neuromuscular blockade for facilitation of ET intubation
Term
Succinylcholine
Adverse effects
Definition
Anaphlyactoid reactions, respiratory depression, apnea, bronchospasm, cardiac arrhythmias, malignant hyperthermia, hypertension, hypotension, muscle recirculation, postprocedure muscle pain, hypersalivation, rash
Term
Succinylcholine
Contraindications
Definition
Malignant hyperthermia, burns, trauma. Use with caution in children, cardiac disease, hepatic disease, renal, disease, peptic ulcer disease, cholinesterase-inhibitor toxicity, psuedocholinesterase deficiency, digitalis toxicity, glaucoma, hyperkalemia, hypothermia, rhabdomyloysis, myasthenia gravis
Term
Succinylcholine
Dosage adult
Definition
IV: 0.6 mg/kg IV, IO Range 0.3-1.1 mg/kg
IM: 3 to 4 mg/kg max dose 150 mg
Term
Succinylcholine
Dosage pediatric
Definition
IV:
adolescents and older children: 1 mg/kg IV, IO
small children and infants: 2 mg/kg IV, IO
IM: 3 to 4 mg/kg max dose: 150 mg
Term
Succinylcholine
Special considerations
Definition
IV administration results in neuromuscular blockade in 0.5 to 1 minute. IM administration results in neuromuscular blockade in 2 to 3 minutes.
IV administration in infants and children can potentially result in profound tachycardia and, in some cases, asystole. This can be reduced with pretreatment of atropine.
Have prolonged effects in presence of nerve gas and organophosphate pesticides.
Pregnancy class C
Term
Prednisone
Trade name
Definition
None
Term
Prednisone
Classification
Definition
Corticosteroid
Term
Prednisone
Action
Definition
Reduces inflammation
Term
Prednisone
Adverse effects
Definition
Typically seen with long term use and withdrawal
Term
Prednisone
Contraindications
Definition
Cushing's syndrome, fungal infections, measles, varicella, known sensitivity
Term
Prednisone
Dosage adult
Definition
Dosage must be individualized
Term
Prednisone
Dosage pediatric
Definition
Dosage must be individualized
Term
Vecuronium Trade Name
Definition
Norcuron
Term
Vecuronium Classification
Definition
Neuromuscular blocker, nondepolarizing
Term
Vecuronium Action
Definition
Antagonizes the ACH receptors at the motor end plate producing skeletal muscle paralysis
Term
Vecuronium Indications
Definition
To induce neuromuscular blockade for facilitation of ET intubation
Term
Vecuronium Adverse Effects
Definition
muscle paralysis, apnea, dyspnea, respitory depression, sinus tachycardia, urticaria
Term
Vecuronium Contraindications
Definition
Use with caution in heart disease liver disease
Term
Vecuronium Dosage Adult
Definition
0.08-0.1 mg/kg IV IO
Term
Vecuronium Dosage Pediatric
Definition
Dosage must be individualized
Term
Vecuronium Special Considerations
Definition
Pregnancy Class C
Term
Rocuronium Trade Name
Definition
Zemuron
Term
Rocuronium Classification
Definition
Neuromuscular blocker, nondepolarizing
Term
Rocuronium Action
Definition
Antagonizes ACH at the motor end plate producing skeletal muscle paralysis
Term
Rocuronium Indications
Definition
To induce Neuromuscular blockade to facilitate ET intubation
Term
Rocuronium Adverse Effects
Definition
muscle paralysis, apnea, dyspnea, respiratory depression, sinus tachycardia, urticaria
Term
Rocuronium Contraindications
Definition
Use with caution in heart disease, liver disease
Term
Rocuronium Dosage Adult
Definition
0.6-1.2 mg/kg IV IO
Term
Rocuronium Dosage Pediatric
Definition
>3 Months 0.6 mg/kg IV IO
Term
Rocuronium Special Considerations
Definition
Onset is 2-8 min
duration of action 31 min
Pregnancy Class B
Term
Etomidate Trade Name
Definition
Amidate
Term
Etomidate classification
Definition
hypnotic anesthesia induction agent
Term
Etomidate action
Definition
appears to have GABA-like effects
Term
Etomidate Indications
Definition
induction for RSI and pharmacologic-assisted intubation, induction of anesthesia
Term
Etomidate adverse effects
Definition
hypotension, respitory depression, pain at injection site, temporary involuntary muscle movements,frequent n/v, adrenal insufficiency, hyperventilation hypoventilation, apnea, hiccups, laryngospasms, snoring, tachypnea, hypertension, cardiac arrythmias
Term
Etomidate contraindications
Definition
use in pregnancy only if the potential benefits justify the potential risk of the fetus. do not use during labor and avoid use in nursing mothers.
Term
Etomidate Dosage Adult
Definition
.2-.6 slow mg/kg IV IO over 30-60 seconds
typical dose is 20 mg slow IV.
Consider less in elderly or patients with cardiac conditions
Term
Etomidate Dosage Pediatric
Definition
>10 years same as adult dosage
<10 years safety not established
Term
Etomidate Special Considerations
Definition
Etomidate is used to prepare a patient for orotracheal intubation. personel and equipment must be present to manage airway before administration
Pregnancy class C
Term
Methylprednisone Trade Name
Definition
Solu-Medrol
Term
Methylprednisone Class
Definition
Corticosteroid
Term
Methylprednisone Action
Definition
Reduces Inflamation by multiple mechanisms
Term
Methylprednisone Indications
Definition
anaphylaxis asthma COPD
Term
Methylprednisone Adverse Effects
Definition
depression, euphoria, headache, restlessness, hypertension, bradycardia, n/v, swelling, diarrhea, weakness, fluid retention, paresthesias
Term
Methylprednisone Contraindications
Definition
cushings syndrome, fungal infections, measles, varicella. use with caution in active infections, renal disease, penetrating spinal cord injury, hypertension, seizures, CHF
Term
Methylprednisone Dosage Adult
Definition
Asthma COPD:
40-80 mg IV
Anaphylactic Shock:
1-2 mg/kg/dose then .5-1 mg/kg every 6 hours
Blunt Spinal Cord Injury:
30mg/kg/hrX1 IV IO then as infusion run dose of 5.4mg/kg/hr for 23 hours
Term
Methylprednisone Dosage Pediatric
Definition
Asthma and COPD:
1 mg/kg (up to 60mg) IV IO per day in 2 divided doses
Anaphylactic Shock:
Same as adult dosing (1-2 mg/kg/dose then .5-1 mg/kg every 6 hours
Blunt spinal cord injury:
Same as adult (30mg/kg/hrX1 IV IO then infusion of 5.4 mg/kg/hr for 23 hours)
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