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PANCE
cytokine review
16
Medical
Graduate
01/27/2008

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Term
IL-1
Definition
Primarily stimulate of fever response. Helps activate B and T cells. Produced by
macrophages.
Term
IL-2
Definition
Aids in the development of Cytotoxic T cells and helper cells. Produced by helper T cell
Term
IL-3
Definition
Aids in the development of bone marrow stem cells. Produced by T-cells.
Term
IL-4
Definition
Aids in the growth of B cells. Produced by helper T-cells. Aids in the production of IgG
and IgE
Term
IL-5
Definition
Promotes the growth of eosinophils. Produced by helper T-cells. Also promotes IgA
production.
Term
IL-8
Definition
Neutrophil factor
Term
TNF-alpha
Definition
Promotes the activation of neutrophils and is produced by macrophages.
Term
TNF-beta
Definition
Produced by T lymphocytes and encourages the activation of neutrophils
Term
gamma-interferon
Definition
Activates macrophages and is produced by helper T cells.
Term
Celiac dz
Definition
anti-gliadin
Term
Goodpasture's
Definition
anti-basement membrane
Term
Hashimoto's thyroiditis
Definition
anti-microsomal
Term
Pemphigus vulgaris
Definition
anti-epithelial
Term
Rhematoid arthritis
Definition
Anti-IgG
Term
Scleroderma (CREST)
Definition
anti-centromere
Term
SLE
Definition
antinuclear antibodies
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