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PANCE PANRE Study Guide
Prep for PANCE and PANRE
720
Medical
Professional
03/12/2014

Additional Medical Flashcards

 


 

Cards

Term
Diarrhea, Primary Hyperaldosteronism and Furosemide therapy can all cause...
Definition
Hypokalemia
Term
An increase in C-reactive protein (CRP) is associated with...
Definition

Acute inflammatory conditions, many... including Myocardial Infarction

CRP is significantly increased in patients with AMI shortly after the onset of symptoms, supporting the hypothesis that, in addition to plaque rupture, acute-phase markers of inflammation may also be elevated as a result of reperfusion injury caused by abrupt closure of the infarct-related artery and by initiation of a thrombolysis or revascularization procedure in patients with AMI.

Term
Increased afterload and left ventricular hypertrophy (LVH) are associated with...
Definition
Diastolic Heart Failure
Term
Alzheimer's, ETOH Chronic Abuse, Parkinson's and Huntington's Chorea are all associated with what condition?
Definition
Dementia
Term
Clinical triad including hypertension, bradycardia and irregular respirations associated with intracranial pathology such as head trauma or hemorrhage
Definition

Cushing's Triad

Cushing's triad refers to a set of signs that are indicative of increased intracranial pressure (ICP), or increased pressure in the brain. 

Term
Modified Jones Major Criteria for Acute Rheumatic Fever
Definition
Major: Erythema marginatum, Carditis, Chorea, Subcutaneous Nodules, Polyarthritis
Term
Modified Jones Minor Criteria for Acute Rheumatic Fever
Definition
Minor: Fever, Arthralgia, Elevated ESR and/or CRP, Prolonged PR interval.
Term
Cobblestone appearance of colon
Definition
Crohn's dz (intermittent pattern of dz causes cobblestone appearance)
Term
Ulcerative colitis affects what part of colon?
Definition
long sections or complete colon (not intermittent like Crohn's) including rectum
Term
An immune reaction affecting the absorption of nutrients in the small intestine
Definition
Celiac Sprue
Term
Sign when abdominal pain is found with flexing the hip and knee indicates what?
Definition

Tight Psoas / Psoas Syndrome

 

sometimes indicates appendicitis.

Term

 

What is the Whipple triad?

Definition

The Whipple triad consists of a history of:

  • hypoglycemic symptoms,
  • a fasting blood glucose of 45 mg per dL or less, and
  • immediate recovery on administration of glucose.
Term
Descriptive sign with clenched fist over sternum to describe dull pressure CP of angina?
Definition
Levines sign
Term

A global esophageal motor disorder in which peristalsis is decreased and lower esophageal sphincter tone is increased, causing slowly progressive dysphagia with episodic regurgitation and chest pain.

 

Condition?

Definition

 

Esophageal Achalasia

Term
Five main features of CREST syndrome?
Definition
Calcinosis
Raynaud's syndrome
Esophageal dysmotility
Sclerodactyly
Telangiectasia
Term
Most common cause of Reiter's syndrome:
Definition
Chlamydia
Term
This dz causes inflammation of urinary tract, eyes, skin, mucous membranes and joints?
Definition

Reiter's syndrome

(now called Reactive Arthritis)

Term
A genetic condition where females are missing all or part of an X Chromosome?
Definition
Turner syndrome
Term
Symptoms of Turner syndrome?
Definition
infertility, amenorrhea, short stature, webbed neck
Term
Signs of Congenital syphilis?
Definition
Painful looking swollen joints, notching of maxillary incisors, hx blindness, deafness.
Term
Painless yellow raised patches on bilat eyelids (dx and associated hx)
Definition
Xanthelasma, hx of high cholesterol
Term
A chronic parasitic infection caused by eating bad pork?
Definition
Schistosmiasis
Term
Most common malignant brain tumor (more common in children)?
Definition
Medulloblastoma
Term
Jaundice, fever, RUQ pain in the presence of ascending cholangitis?
Definition
Charcot's triad
Term
Bacterias associated with Endocarditis:
Definition
Acute: Staph Aureus
Subacute: Strep Veridan, Enterococci
Term
What is the Duke Criteria and what does it identify?
Definition
identifys Bacterial Endocarditis
Major Criteria:
Positive blood culture for Infective Endocarditis
Minor criteria :
*Predisposition: predisposing heart condition or intravenous drug use
*Fever: temperature > 38.0° C (100.4° F)
*Vascular phenomena: major arterial emboli, septic pulmonary infarcts, mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhages, and Janeway lesions
*Immunologic phenomena: glomerulonephritis, Osler's nodes, Roth spots (what's this?), and rheumatoid factor
*Microbiological evidence: positive blood culture but does not meet a major criterion as noted above¹ or serological evidence of active infection with organism consistent with IE
*Echocardiographic findings: consistent with IE but do not meet a major criterion as noted above
Term
Vasculitis of small and medium vessels of extremities is:
Definition
Buerger's Dz (thromboangitis)
Term
Classic triad: intermittent claudication, Raynauds and migratory superficial thrombophlebitis, indicates:
Definition
Buerger's Dz
Vasculitis of small and medium vessels of extremities
Term
How do you diagnose Buerger's dz?
Definition
bx of vessel
Term
Pulsus bisferiens. What is it? When is it seen?
Definition
palpation of double pulse felt w/each beat. felt in pt's with hypertrophic cardiomyopathy
Term
hypertrophic cardiomyopathy:
Inherited or not?
Definition
Autozomal dominant, inherited familial dz
Term

These account for about 6-10% of cases of congenital heart disease. 34yo male cc: dyspnea and CP.

  • Widely split and fixed S2 into A2, Ps (lub, dub-dub).
  • Murmur: grade II-III/VI systolic ejection murmur at left 2nd or 3rd intercostal space (pulmonic area).

Dx?

Definition

ASD

Echocardiography - DEFINITIVE DIAGNOSIS will demonstrate a septal defect.

ECG may show right axis deviation, right ventricular hypertrophy, or right bundle branch block

Chest x-ray shows cardiomegaly with dilatation of the right atrium and right ventricle

Term
Harsh, late systolic murmur heard at base and posteriorly. Dx?
Definition
coarctation of the Aorta
Term
Machinery like murmur. Dx?
Definition
PDA (Patent ductus arteriosus)
Term
Harsh, late systolic murmur with prominent thrill heard at Left 2nd/3rd ICS. Dx?
Definition
Pulmonary Stenosis
Term
Pulmonary Stenosis EKG
Definition
RAD, RVH, Peaked P-waves
Term
VSD, RV outflow obstruction (pulmonary stenosis), RVH, overriding (large) aorta
Definition
Tetrology of Fallot
Term
CXR of Tetrology of Fallot pt:
Definition

[image]

boot shaped heart sihlouette 

Term

4-year-old boy who is brought to your office by his parents because he gets tired very easily and cannot keep up with the other children.

On exam, you hear A midsystolic pulmonary flow or ejection murmur is present and a fixed, split S2.

 

Dx?

Definition
ASD
Term
CHF confirmed with which tests?
Definition
CXR, ECHO, Swan Ganz Cath is primary
Term
sequelae to hemolytic strep infection
Definition
Rheumatic Heart dz
Term
Rapid "bag of worms" action of tongue when tongue protrudes
Definition
Sydenham's Chorea, seen in Rheumatic heart dz
Term
Opening snap heart sound heard at apex mid-diastolic
Definition
Mitral stenosis
Term
Most common sign of Sickle Cell in first few months of life:
Definition
Failure to thrive - earliest sign of Sickle Cell
Term
epigastric pain, relived by food, worsened by hunger
Definition
duodenal ulcers
Term
Tamsulosin is an alpha-blocker used to treat:
Definition
BPH
Term
Treatment for Pertussis (Whooping Cough)
Definition
Erythromycin
Term
The most important way to prevent pertussis (whooping cough):
Definition
DTaP vaccine
Term
Dacryoadentitis is:
Definition
Infection of the eye due to clogged tear duct(s). sx include medial eye redness, swelling, LAD
Term
Phalen's maneuver is used to diagnose:
Definition
Carpal tunnel
Term
caused by a defect of Chromosome 21
Definition
Down Syndrome
Term
Turner syndrome is...
Definition
a missing all or part of an X Chromosome seen only in females.
Term
symptoms include, infertility, amenorrhea, short stature and webbed neck. what Dx?
Definition
Turner syndrome
Term
Klinefelter's syndrome s+sx
Definition
seen in males, poor muscle strength, infertility, gynocomastia, low testosterone.
Term
Male only syndrome resulting in having an extra Y Chromosome:
Definition
Kleinfelter's syndrome
Term
Triad seen as a result of pericardial effusion?
Definition
Becks Triad
Term
distended jugulars, hypotension and muffled heart sounds are what triad and what dz process?
Definition
Becks Triad seen in pericardial effusion
Term
what cells located in the islets of Langerhans secrete insulin?
Definition
Beta Cells
Term
What cells in the liver produce glucagon?
Definition
Alpha cells
Term
what do the gamma cells in the pancreas secrete?
Definition
a specialized type of peptide designed to reduce appetite
Term
what do the delta cells in the pancreas secrete?
Definition
somatostatin, plays a role in food absorption
Term
Tx for H-pylori
Definition
combination of two abx (amoxil, clarithromycin, flagyl, tetracycline) and a PPI
Term
Parkinson's dz destroys dopamine producing cells in the:
Definition
substantia nigra
Term
before onset of Parkinson's sx, what percent of the substantia nigra is destoyed?
Definition
80%
Term
The medulla oblongotta helps control what systems
Definition
Involuntary sympathetic and parasympathetic systems,, respirations and simple reflexes.
Term
LBBB acts as a red flag for these 4 conditions:
Definition
severe aortic valve dz, ischemic heart dz, chronic HTN, cardiomyopathy
Term
VSD, pulmonary outflow tract limitation, RVH (rt vent hypertrophy) and overriding aorta are all parts of:
Definition
tetrology of fallot
Term
Most common congenital heart defect:
Definition
VSD
Term
gram pos coccus responsible for common skin infectiions:
Definition
Staph aureus
Term
right sided heart failure cause by pulmonary HTN
Definition
Cor Pulmonale
Term
standard test to diagnose cystic fibrosis
Definition
sweat chloride test
Term
an autosomal recessive genetic blood d/o caused by a defect of chromosome 11 is:
Definition
Sickle Cell dz
Term
a deficiency in factor VIII
Definition
Von Willebrand dz
Term
a genetic dz causing inadequate hemoglobin production and a cause of chronic anemia:
Definition
Thalassemia
Term
Cancer of the plasma cells:
Definition
Myeloma
Term
Cancer of the plasma cells, presents with anemia, but also can cause bone pain, infection, fatigue, loss of bowel/bladder fxn:
Definition
Myeloma
Term
Hip and knee pain, gait disturbance seen in prepubescent and pubescent children who are going through a growth spurt:
Definition
Slipped Capital femoral epiphysis
Term
Treatments for paget's dz:
Definition
Biphosphonates (fosamax), NSAIDS and calcitonin
Term
Most common presentation for this dz is unilateral vision loss:
Definition
Retinal artery occlusion
Term
common comorbitidies for Retinal artery occlusion:
Definition
DM, coagulopathy d/o's, HTN, advanced atherosclerosis
Term
Bacteria which is the most common pathogen in swimmer's ear:
Definition
Pseudomonas aeruginosa
Term
Tamsulosin is an alpha blocker used to treat what condition?
Definition
BPH
Term
Tx for whooping cough?
Definition
EES
Term

[image]

what does this show and what is the tx?

Definition

Pneumocystis carini (bat wings)

TMP-SMX

Term
Tx plan for a newborn with PKU (phenylketonuria)
Definition
dietary restrictions. Pts with PKU are unable to break down phenylalanine, a common amino acid found in foods..
Term
Listeriosis is:
Definition
a bacteria found in contaminated food.
washing foods, pasteurized milk and cooking meats well helps avoid listeriosis
Term
friction rub heart sound is heard in which dz?
Definition
pericarditis
Term
widely split S2 sound is heard in which dx?
Definition
RBBB
Term
opening snap heart sound, what dx?
Definition
Mitral stenosis
Term
mid systolic click heart sound, what dx?
Definition
Mitral Valve prolapse
Term
Tx for young pt with 1o HTN
Definition
ACE-I
Term
tx for middle aged pt with HTN
Definition
a-blocker, ACE-I, CCB
Term
tx of HTN with +angina
Definition
CCB
Term
causes of myocarditis
Definition
most common: Idiopathic (viral), other causes Rheumatic, Lyme dz, autoimmune
Term
s+sx: new onset CHF, URI/fever sx x 2-3wks. dx?
Definition
myocarditis
Term
labs expected with myocarditis?
Definition
Elevated CPK, Troponin and ESR
Term
Echo shows 2 echo signals behind left ventricle. dx?
Definition
pericardial effusion, tamponade
Term
JVD in inspiration = what sign and what dx?
Definition
Kussmaul's sign seen in pericardial tamponade
Term
water bottle appearance of heart on CXR
Definition
tamponade
Term
sequelae to untreated hemolytic strep infection:
Definition
Rheumatic heart dz
Term
rapid "bag of worms" action of tongue when pt asked to protrude tongue:
Definition
Sydenham's chorea (seen in Rheumatic heart dz)
Term
criteria used to dx Rheumatic heart dz?
Definition
Ducket-Jones criteria
Term
high pitched heart sounds usually indicate:
Definition
valve regurgitation
Term
high pitched diastolic crescendo murmur suggests:
Definition
Aortic regurg
Term
murmur heard at apex, high pitched pansystolic
Definition
Mitral regurg
Term
heart sounds: opening snap, murmur at apex, low mid diastolic rumble
Definition
Mitral stenosis
Term
1o cause of mitral stenosis and regurg:
Definition
Rheumatic heart dz
Term
heart sounds: mid to late systolic click heard at apex, high pitched late systolic crescendo-decrescendo increased with standing
Definition
MVP
Term
who gets MVP?
Definition
thin females, 14-30 y/o and Marfan pts
Term
EKG= biphasic or inverted T's in inferior. dx?
Definition
MVP - echo is diagnostic
Term
murmur: harsh higher pitched systolic blowing sounds at left lower sternal border
Definition
Tricuspid regurg
Term
murmur: diastolic rumble at left lower sternal border
Definition
Tricuspid stenosis
Term
Ascites, olive skin, dependent edema, fluttery discomfort in neck. dx?
Definition
Tricuspid stenosis
Term
sx: sever profound dyspnea after trauma, aspiration or acute dz with poor response to O2 unless CPAP assisted.
Definition
ARDS
Term
3 criteria for ARDS dx:
Definition
1- CXR = patchy infiltrates w/o costophrenic angles affected.
2- hypoxemia (ABGs or SpO2)
3- abscence of pulmonary edema
Term
Vent mgt for ARDS
Definition
1- permissive hypercapnia
2- avoid O2 toxicity, increased PEEP not FiO2
Term
CXR = ground glass appearance
PFTs restrictive pattern
Definition
asbestos pneumoconiosis
Term
PFT's= dec FEV, inc TLC and RV
dx?
Definition
Asthma
Term
ABGs of severe asthma:
Definition
Resp alkalosis, hypoxemia, metabolic acidosis
Term
Bronchospasm precipitated by CHF
Definition
Cardiac asthma
Term
triad of persistent productive cough, copious purulent sputum, hemoptysis
Definition
Bronchiectasis
Term
cause of 50% of all bronchiectasis?
Definition
Cystic fibrosis
Term
Blue Bloater vs. Pink puffer
Definition
Blue Bloater = chronic Bronchitis (BB=B)
Pink puffer = emphysema (PP=E)(PPE)
Term
PFTs of restrictive lung dz (asthma)
Definition
FEV1 low / FVC low,vlow
FEV1/FVC ratio is either = or up
Term
PFTs of obstructive lung dz COPD, chronic bronchitis
Definition
FEV1 low,vlow / FVC nl
FEV1/FVC ratio is low
Term
Cause of and tx of anaerobic pneumonia
Definition
Cause: aspiration
Tx: Pen-G, Cleocin, draining of abscess or aspirate
Term
sx of TB
Definition
cough, started dry, now progressed to productive and bloody, night sweats
Term
meds tx for latent TB
Definition
isoniazid x 9 mos, rifampin x 4 mos
Term
tx for active TB
Definition
isolation, isoniazid and rifampin x 6 mos, pyrazinamide x 2 mos
Term
Lung dz which is a systemic granulomatous inflammatory d/o of unknown cause:
Definition
sarcoidosis
Term
CXR for sarcoidosis:
Definition
bilat hilar LAD
Term
bx of lung, skin or liver lesion shows noncaseating granuloma. dx?
Definition
sarcoidosis
Term
sx: progressive dysphagia, vomiting after eating, nocturnal cough
Definition
esophageal achalasia
Term
X-ray of esophageal achalasia:
Definition
bird beak narrowing at LES
Term
etiology of esophageal achalasia:
Definition
dysfxn of esophageal smooth muscle, persistent increased LES tone, failure of LES to relax.
Term
nonsurgical tx for esophageal achalasia:
Definition
nitrates and CCBs for smooth muscle relaxing.
Term
tx for ETOH hepatitis (Rx and non rx):
Definition
Folate, B12, Thiamine and Rx prednisone for 4 weeks.
Term
Leukocytosis with bowel obstruction suggests which dx?
Definition
strangulated bowel
Term
plexus of dilated veins around umbilicus. name and dz?
Definition
Caput Medusa from cirrhosis of and obstruction of portal vein,
Term
type of CA which is common in colon ca
Definition
adenocarcinoma
Term
CEA test for colon ca. best use of test.
Definition
recurrence or mets
Term
Cotton Wool spots seen on fundoscopic exam suggest:
Definition
DM, HTN, HIV, anemia
Term
Full thickness dx of colonic wall affecting any portion of GI tract
Definition
Crohn's dz
Term
part of GI tract most often affected by crohn's dz
Definition
ileum, but can be found anywhere and can have skip lesions
Term
thumb points seen on colon x-ray, although CT is diagnostic
Definition
diverticulitis
Term
columnar epithelium replaces nl squamous epithelium of distal esophagus in what dz?
Definition
Barrets esophagitis
Term
1o type of stomach ca:
Definition
adenocarcinoma 95%
Term
what are the types of esophageal carcinomas and from what etiologies?
Definition
squamous cell (ETOH,smoking), adenocarcinoma (Barrets)
Term
What asthma classification if sx are <2x/week with night sx <2x/month?
Definition
mild intermittent asthma
Term
What asthma classification if sx are 3-6x/week with night sx 3-4x/month?
Definition
mild persistent asthma
Term
What asthma classification if sx are qd with night sx 5+ times/month?
Definition
moderate persistent asthma
Term
What asthma classification if sx are continuous and frequent night sx?
Definition
severe persistent asthma
Term
most common cause of chronic gastritis
Definition
H-pylori
Term
gastritis caused by ETOH use, NSAIDS, stress etc. (dx and tx)
Definition
acute erosive gastritis. tx includes H2 blockers, PPI, antacids
Term
sx: chronic hepatitis, cirrhosis, DM, CHF, bronze skin, arthritis, pituitary dysfxn. constellation of sx caused by:
Definition
hemochromocytosis. iron overload. affects all organs,systems
Term
tx for hemochromocytosis:
Definition
weekly phlebotomy, iron chelator if pt not tolerant of phlebotomy
Term
labs and tests for hemochromocytosis:
Definition
elevated serum iron (>300mg/dl), elev transferrin saturation (>50%), elev urine iron secretion, liver bx is diagnostic.
Term
autosomal recessive dz where there is decreased copper secretion and increased storage and copper deposits. affects liver and brain and/or eyes.
Definition
Wilson's dz
Term
confirmatory test for Wilson's dz:
Definition
liver bx
Term
Hep-B immunity is seen with which test result?
Definition
having Anti-HBsAg (anti Hep-B surface antigen)
Term
IgG vs IgM vs IgE
Definition
IgG is antibody immunity to viral and bacterial infections, no active dz (dz danger is IgGone)
IgM is active disease
IgE is allergic reaction
Term
dx of large bowel, bloody diarrhea, tenesmus
Definition
ulcerative colitis
Term
bilirubin level of jaundice infant at 3 day old and cause
Definition
Bilirubin 12-15, likely cause = breast milk
Term
most common cause of liver abscesses
Definition
entamoeba histolytica or bacteria
Term
labs to indicate liver abscess
Definition
elevated WBCs & liver enzymes, Antiameobic serum antibodies (+) in >90% of pts
Term
cause of Mallory Weiss tear
Definition
prolonged vomiting
Term
Levels of obesity with BMI
Definition
Mild = BMI of 27.5-30
Moderate = BMI of 30-40
Morbid = BMI of >40
Term
type of ca for pancreatic ca
Definition
adenocarcinoma
Term
gold standard for diagnosing 1o sclerosing cholangitis
Definition
ERCP
Term
tx to cure 1o sclerosing cholangitis
Definition
Liver transplant
Term
lead pipe look of colon on abd x-ray is late stage finding of what dz?
Definition
Ulcerative Colitis
Term
nerve dz associated with fx's at key joints or nerve pathways
Definition
RSD - reflex sympathetic dystrophy
Term
inflammatory polyarthropathy with sacroiliitis and (+) HLA-B27
Definition
ankylosing spondylitis
Term
diagnostic labs for ankylosing spondylitis
Definition
(+) HLA-B27
elevated ESR
Term

 

Rx's to treat ankylosing spondylitis

Definition

NSAIDs first, then

 

TNF inhibitors, which include etanercept, infliximab.

Anti-interleukin (IL) 17 antibodies, which include secukinumab and ixekizumab.

Janus kinase (JAK) inhibitors, which include tofacitinib and upadacitinib.

Term
Segund fx - what is it and what does it indicate?
Definition
Avulsion fx of proximal lateral tibial cortex associated with ACL and +/- MCL injury.
Term
bowing of legs bc of poor bone growth of medial tibia seen in 2-4 y/o kids
Definition
Blount's dz (Blounts bows)
Term
de quervain's tenosynovitis location
Definition
base of thumb
Term
pain on passive extension of hand. what is this sign and what does it indicate?
Definition
Kanavels sign, seen in flexor tenosynovitis of the hand.
Term
tx for flexor tenosynovitis of the hand:
Definition
Surgical I+D, IV abx, maybe occ therapy.
S.aureus is bug
Term
most common ca's which mets to bone:
Definition
Breast, Liver Thyroid, prostate and kidneys.
(remember BLT with pickles and ketchup)
Term
degeneration of interdigit nerve 2o to entrapment/compression. most common in 3rd web space of foot.
Definition
Morton's neuroma
Term
What are Bouchard's and Heberden's nodes?
Definition
hard nodules at PIP and DIPs associated with osteoarthritis
Term
Urethritis, conjunctivitis and polyarthritis
Definition
Reiter's syndrome
Term
Malar (cheek-bones) rash is 1o initial sign.
Also discoid rash, photosensitivity, renal d/o, Immunologic d/o, abnl ANA
Definition
Lupus (SLE)
Term
apothus ulcers form in what tissue
Definition
unkaratinized mucosa, not in keratinized tissue
Term
sudden unilateral painless vision loss, sluggish pupil, edematous macula:
Definition
Central retinal artery occulsion
Term
bacterial pathogens of conjunctivitis
Definition
Strep pneumonia, Staph sp, n. gonorrhea, chlamydia, Hem. influenza
Term
viral pathogens of conjunctivitis
Definition
adenovirus, HSV, Varicella, EBV, Flu, coxacky
Term
box car appearance of vessels on fundoscopic exam, pale optic disk, cherry red fovea
Definition
central retinal artery occlusion.
Term
sudden eye pain, blurred vision, rainbow halo around lights
Definition
acute angle closure glaucoma
Term
gradual loss of peripheral vision, eventually tunnel vision, halos around lights
Definition
Glaucoma, 1o open angle
Term
Fundoscopic exam: disk margins are thin, cup is wider and deeper, atrophic disk area
Definition
Glaucoma, 1o open angle
Term
meds and tx for open 1o open angle Glaucoma
Definition
miotics and laser trabeculoplasty
Term
ptosis (drooping of eyelid) miosis (constriction of pupil) and anhydrosis (decreased or no sweating) is the three sx of:
Definition
Horner's syndrome
Term
What does a Rinne test evaluate?
Definition
Hearing loss. Using tuning fork in air and on mastoids. Test for conduction loss (BC>AC) and Sensorial loss (AC>BC)
Term
The Weber test is a quick screening test for what?
Definition
Unilateral Hearing loss. Tuning fork is placed center forehead, and center top of head. pt sts if sounds are equal or lesser in 1 side. nl is =
Term
dome shaped elevation of retinal pigment membrane and depigmentation of area of retina:
Definition
macular degeneration (MD). dry MD 90% of MD. tx: none, wet MD. 10% of MD tx: laser photocoagulation. More extensive vision loss with wet form.
Term
treatment for macular degeneration (MD):
Definition
dry MD tx: none, wet MD tx: laser photocoagulation
Term
characterized by the presence of yellow deposits, called drusen, in the macula. What is it?
Definition
dry form (age related) of macular degeneration. tx = none
Term
characterized by the growth of abnormal blood vessels from the choroid underneath the macula. This is called choroidal neovascularization. What is it?
Definition
Wet form (age related) of macular degeneration. tx = laser photocoagulation
Term
Sudden onset, unilat vision loss with pain with EOMs. central vision loss, decreased color vision. swollen optic disk
Definition
Optic neuritis (MRI will show multiple white matter lesions on brain)
Term
tx and prognosis for optic neuritis dx?
Definition
Tx: observation, +\- steroids, sx progress for few days, plateaus an then slow resolving. total time 6-8 weeks.
Term
Otitis Externa pathogens:
Definition
Gm- Pseudomonas species (38% of all cases) and Staphylococcus species
Term
Otitis Media pathogens:
Definition
Strep Pneumonae, H influenzae or M catarrhalis
Term
floaters and flashers are seen with what eye problem:
Definition
retinal detachment
Term

 

A 59-year-old male complains of "flashing lights behind my eye" followed by a sudden loss of vision, stating that it was "like a curtain across my eye." 

 

likely dx?

Definition

 Retinal detachment.

An ophthalmologic emergency!

  • Flashes/floaters,
  • curtain closing,
  • usually unilateral vision loss,
  • defects noted on peripheral visual field exam.
Term
Meneres dz vs. benign vertigo
Definition
Meneres dx is chronic, BPVertigo is temporary
Term
what causes Meneres dz?
Definition
distension of lymphatic compartment of inner ear.
Term
hypertrophy of myometrium caused my endometrial tissue forming in myometrium.
Definition
Adenomyosis
Term
Adenomyosis: hypertrophy of myometrium caused my endometrial tissue forming in myometrium. What is tx?
Definition
NSAIDS for sx care. Hysterectomy is cure.
Term

CA type(s) for cervical carcinoma?

 

and 

Disease exposure risk factor?

Definition

 

SCC (75%), Adenosquamous (25%)

 

In almost all cases, cervical cancer is due to human papillomavirus (HPV) infection.

Term
sudden, unilateral pelvic pain with +\- radiation to shoulder. dx?
Definition
ectopic pregnancy
Term
ectopic tx includes methotrexate if size is less than...
Definition
3.5cm
Term
The presence of functioning endometrial tissue outside the uterus is the etiology of what dx?
Definition
endometriosis
Term
The triad of cyclical pelvic pain, dyspareunia and infertility is associated with what dz?
Definition
endometriosis
Term
gold standard for diagnosing endometriosis:
Definition
Laparoscopy
Term
Hormone Replacement Tx (HRT) has two 1o benefits in women:
Definition
1) menopausal sx tx.
2) osteoporosis tx (fx prevention)
Term
which pt's are excluded from HRT (Hormone replacement therapy)?
Definition
Pt's with hx of DVT, CAD, CVA, Breast CA, Pregnant, Liver dz
Term
Abnl uterine bleeding in 1st trimester with noted passage of vesicular tissue:
Definition
Hydatidiform Mole
An abnl pregnancy with multiple grape like vesicular appearance (sono), filling and distending the uterus.
Term
An abnl pregnancy with multiple grape like vesicular appearance (sono), filling and distending the uterus.
Definition
Hydatidiform Mole
Term
What is the most common gestational trophoblastic neoplasm?
Definition
Hydatidiform Mole
Term
Mastitis: dx with exam or sono.
What is most common pathogen?
Definition
Staph Aureus
Term
Lab to confirm menopause:
Definition
Serum FSH
Term
APGAR scores
Definition
Appearance
Pulse
Grimace
Activity
Respiration
Performed at 1 and 5 min postpartum
Term
what are the 3 stages of labor?
Definition
First stage, the cervix dilates as a result of progressive rhythmic uterine contractions.
Second stage of labor is the time between complete cervical dilation and delivery of the neonate
3rd stage is delivery of placenta
Term
HAIR-AN synd consists of hyperandrogenism (HA), insulin resist. (IR), and acanthosis nigricans (AN)
HAIR-AN is seen in which dz?
Definition
PCOS
polycystic ovary syndrome
Term
Labs and imaging to determine PCOS
Definition
FSH, LH, DHEA-S, TSH, HgbA1-C, glucose
Pelvic US confirms
Term
Medication to treat hirsutism in PCOS pts:
Definition
Spironolactone
Term
one of the dangers of Preeclampsia is HELLP. What is HELLP?
Definition
Hemolysis,
Elevated
Liver enzymes,
Low
Platelet count
Term
Tzank smear is used to identify what dz?
Definition
HSV
Term
Painful vs painless ulcers on the penis
Definition
Painful penis ulcers = chancroid
Painless penis ulcers = syphilis
Remember syphilisss is painlessss
Term
Most common type of prostate CA
Definition
adenocarcinoma
Term
1o bug of vaginitis
Definition
Trichomoniasis
Term
Cervical friability, +nodules seen
mostly asymptomatic, but can have vaginal bleed and vaginal pain
Definition
HPV
Term
Neuro dz from degeneration of the anterior horn motor neurons and corticospinal tracts.
Definition
ALS (Amyotrophic Lateral Sclerosis)
Term
S+Sx= ataxia (progressive, symmetrical and ascending), weakness (more severe proximally), absence of DTRs.
usually follows viral illness. dx?
Definition
Gillian-Barre Synd.
Term
EMG of this progressive ataxic pt shows diffuse demyelination and decreased nerve velocities. What dx?
Definition
Gillian-Barre Synd.
Term
Classic triad of wobbly, wacky and wet (gait d/o, dementia, incontinence) with this likely dx:
Definition
Normal pressure hydrocephalus
Term
Dz develops after 30th yr. Mutation of chromosome 4. sx: involuntary writhing movements, cognitive decline and psychiatric problems
Definition
Huntington's Dz (Chorea)
Term
the most common genetic cause of abnormal involuntary writhing movements
Definition
Huntington's Dz (Chorea)
Term
Cloudy CSF, Higher psi, high WBC, High protein, decreased glucose.
Definition
Bacterial meningitis
Term
dz with alteration of T-lymphocytes, which has multiple foci of demyelination of CNS white matter. relapsing, chronic, progressive:
Definition
MS
Term
CSF of an MS pt.
Definition
mild elevated protein, increased IgG index, oligoclonal bands, increased myelin basic protein
Term
Oligoclonal bands are an important indicator in the diagnosis of
Definition
multiple sclerosis
Term
Tx of MS flairs and prevention of flairs:
Definition
flairs tx = corticosteroids
frequency of flairs reduction = Interferon-B and copolymer.
Term
intracellular neurofibrillary tangles and extracellular neuritic plaques are seen with this dz:
Definition
Alzheimer's
Term
Class of drugs used in Alzheimer's pts to improve memory fxn:
Definition
cholinesterase inhibitors
Term
perivascular release of substance P is one of the causes of this dz:
Definition
Migraine HA
Term
rhythmic 6-8hz, to and fro movement of upper extremities. sometimes head and speech affected.
Definition
Benign essential (familial) tremors
Term
Tx for Benign essential tremors:
Definition
Low dose Beta Blockers
Term

intentional (cerebellar) tremors are a result of what dz's?

Also... Tx?

Definition

Causes include damage or degradation of the cerebellum due to neurodegenerative diseasestraumatumorstroke, or toxicity.

Tx: no known cure, but using same txs for essential tremors has shown some promise.

Term
Asterixis: wrist joint flapping tremors is sign of:
Definition

It can be a sign of hepatic encephalopathy, damage to brain cells presumably due to the inability of the liver to metabolize ammonia to urea.

Term
resting tremor, bradykinesia and rigidity are signs of:
Definition
Parkinsons
Term
What are Kayser-Fleischer rings seen on the cornea?
Definition
Seen in Wilson's dz. copper rings that appear to encircle the iris of the eye. They are due to copper deposition in part of the cornea
Term
Loss of sensation and motor function (paralysis and anesthesia) that is caused by the lateral hemisection (cutting) of the spinal cord. dx?
Definition
Brown-Sequard Syndrome
Term
DSM IV
Axis 1, 2 and 3. What are these?
Definition
Axis 1 - clinical d/o
Axis 2 - personality d/o
Axis 3 - medical condition
Term
Explain schizoid vs. schizotypal personality d/o.
Definition
schizoid - no desire or enjoyment of close relationships.
schizotypal - eccentric behavior, odd, magical beliefs.
Term
behavior where pt disregards rights of others
Definition
antisocial behavior
Term
behavior where pt has intense, but highly unstable relationships:
Definition
borderline behavior
Term
behavior where pt needs to be center of attention:
Definition
histrionic behavior
Term
behavior where pt has a sense of grandiosity and self importance. sense of entitlement, lack of sympathy:
Definition
narcissistic behavior
Term
in dependent personality d/o, the pt feels...
Definition
helpless
Term
in avoidant personality d/o, a person feels...
Definition
in fear of shame or ridicule.
Term
erythema migrans (expanding anular/bulls-eye rash) is seen with this dx:
Definition
Lyme dz
It is a pathognomonic sign
Term
Lyme dz bacteria
Definition
Borrelia burgdorferi
Term
Heinz Bodies and
Elevated Reticulocyte Count dx?
Definition
G6PD anemia
Term
Howell-Jolly Bodies are associated with
Definition
Folic Acid Deficiency
Term
Cheilosis, Atophic Glossitis and Pica are all associated with
Definition
Iron Deficiency Anemia
Term
Basophilic Stippling is seen in:
Definition
  • Sideroblastic anemia
  • Lead poisoning (microcytic anemia)
  • Arsenic poisoning
  • Beta thalassemia 
  • Alpha-thalassemiaHbH Disease
  • Hereditary Pyrimidine 5'-Nucleotidase Deficiency
  • Thrombotic thrombocytopenic purpura
Term
Strict Vegan Diet can lead to:
Definition
Vitamin B12 Deficiency Anemia and Pernicious anemia
Term
Auer rods are seen in what dx?
Definition
AML
Term
Gingival Hyperplasia is seen in
Definition
AML (Acute Myelogenous Leukemia), Sarcoidosis, some neoplasms.
Term
9/22 Translocation is seen in which dx:
Definition
CML
Term
Smudge Cells are seen in which dx?
Definition

 

CLL

 

(also sometimes in Mono)

Term
Common s+sx include pruritus and severe burning pain in the hands or feet that is usually accompanied by a reddish or bluish coloration of the skin.
Definition
Polycythemia Vera
Term
tx for Polycythemia Vera
Definition
phlebotomy (blood letting)
Term
a myeloproliferative blood cancer in which the bone marrow makes too many red blood cells. It may also result in the overproduction of white blood cells and platelets:
Definition
Polycythemia Vera
Term
Tear drop RBCs are seen with which dx:
Definition

Myelofibrosis

a bone marrow neoplasm

Term
Monoclonal Spike seen on electrophoresis.
dx?
Definition
Multiple Myeloma
Term
Reed-Sternberg Cells are giant lymphocytes seen in which dx?
Definition
Hodgkin's Lymphoma
Term
caused by the excessive breakdown and formation of bone, followed by disorganized bone remodeling. Commonly affecting vertebrae, pelvis, femur and cranium:
Definition
Paget's Disease
Term
Tx for Paget's dz?
Definition
No cure, but meds (bisphosphonates and calcitonin) can help control the disorder and lessen pain and other symptoms.
Term
Fragile X Chromosome causes:
Definition
Inherited Mental Retardation and autism
Term
C5 nerve distribution affects
Definition
Deltoid, biceps
Term
C6 nerve distribution affects
Definition
bicep and wrist extension
Term
C7 nerve distribution affects
Definition
tricep down to middle finger
Term
L5 nerve distribution affects
Definition
muscles that raise the foot and big toe
Term
S1 nerve distribution affects
Definition
the large gastronemius muscle in the back of the calf, causing difficulty with foot push off
Term
Spurling's Sign
Definition
Pain with Rotation of Head
Term
Lhermitte's Sign
Definition
Pain with Hyperextension of Neck
Term
Serum concentrations of p24 antigen are high in which early phase of dz?
Definition
Early, Acute HIV infection.
Term
Treponema pallidum is a spirochaete bacterium. It is the 1o bug in this dx:
Definition
Syphilis
Term
a mosquito-borne infectious dz of humans and other animals caused by parasitic protozoans of the genus Plasmodium
Definition
Malaria
Term
tx options for Malaria:
Definition
fluoroquinolones, doxy, cleocin
Term
Finkelstein's Test where the hand is to the side in anatomical position. The provider grasps the thumb and ulnar-deviates the hand sharply. If sharp pain occurs along the distal radius, the pt likely has:
Definition
DeQuervan's Tenosynovitis
Term
Pain with Elbow Extension at lateral elbow is "Tennis Elbow" (lateral epicondylitis). What is likely dx with Pain with Flexion of Elbow and Wrist Pronation
Definition
Golfer's elbow (medial epicondylitis)
Term
Factor 8 Deficiency is classic for:
Definition
Hemophilia A
Term
Cotton Worker common dz, also called "brown lung disease" or "Monday fever":
Definition
Byssinosis
Term
[image]
Definition
Asbestosis
Term
Metallic Iron Exposure causes which dz?
Definition
Siderosis
Term
An occupational lung disease caused by inhalation of crystalline dust by miners, and is marked by inflammation and scarring in the form of nodular lesions in the upper lobes of the lungs
Definition
Silicosis
Term
"Tea Colored" Urine and RBC casts
Definition
Acute Glomerulonephritis
Term
A lung CA which is thought to originate from neuroendocrine cells in the bronchus called Feyrter cells which express a variety of neuroendocrine markers, and may lead to ectopic production of hormones like ADH and ACTH that may result in paraneoplastic syndromes and Cushing's syndrome. Type of CA
Definition
Small cell or Oat cell lung CA
Term
Bird Beak Appearance on Barium Swallow
Definition
Achalasia
Term
Increased abdominal pain with food:
Definition
Gastric Ulcer
Term
Decreased abdominal pain with food:
Definition
Duodenal Ulcer
Term
Palpable Gallbladder also known as Courvier's Sign indicates what dx:
Definition
Pancreatic head CA
Term
Porcelain Gallbladder
Definition
chronic cholecystitis
Term
HLA-B27 surface antigen is strongly associated with:
Definition
ankylosing spondylitis
Term
an autoimmune disease in which the thyroid gland is attacked by a variety of cell- and antibody-mediated immune processes.
Definition
Hashimoto's thyroiditis
Term
Hashimoto's thyroiditis pt are at higher risk for what CA
Definition
Thyroid lymphoma, generally the B-cell type, non-Hodgkin lymphoma.
Term
Increase in ACTH is seen in which dx?
Definition
Addison's dz.
Term
Red Ciliary Flush and high IOP is seen in which dx?
Definition
Acute Glaucoma
Term
Steamy Cornea is seen with what dx?
Definition
Acute angle closure glaucoma
Term
Butterfly Rash, Alopecia, High ANA:
Definition
Lupus
Term
The most common presenting symptom is painless melena followed by intestinal obstruction, volvulus and intussusception. Occasionally, may present with all the features of acute appendicitis
Definition
Meckel's Diverticulum, diverticulitis
Term
Location and gestational development of Meckel's Diverticulum
Definition
at the distal ileum near the iliocecal valve. on the antimesenteric side and has its own blood supply. It is a remnant of the connection from the yolk sac to the small intestine present during embryonic development.
Term
caused by a non–beta islet cell, gastrin-secreting tumor of the pancreas that stimulates the acid-secreting cells of the stomach to maximal activity, with consequent gastrointestinal mucosal ulceration.
Definition
Zollinger–Ellison Syndrome (ZES)
Term
Fine, Pink Maculopapular Rash
Definition
Rubella "German Measles"
Term
Antibodies Against Acetylcholine Receptors, Fatigue with Chewing dx?
Definition
Myasthenia Gravis
Term
Progressive Weakness Upper and Lower Motor Neuron Involved
Definition
ALS
Term
Auspitz's Sign
Definition
Psoriasis
Term
Thickening of the Skin with Telangiectasias
Definition
Scleroderma
Term
Proximal Muscle Weakness
Definition
Polymyositis
Term
Pain and Stiffness without Weakness, Acute Onset, Markedly Elevated ESR dx?
Definition
Polymyalgia Rheumatica
Term

Dry Eyes, Dry Mouth, Dysphagia with Parotid Enlargement. Dx?

 

Who do you refer to?

Definition

Sjogren's Syndrome

 

Refer to Rheumatology

Term

Granulomatosis Inflammation of Lungs

Non-Caseating Granulomas, Erythema Nodosum, Symmetric Bilateral Hilar Adenopathy
Definition
Sarcoidosis
Term
An autoimmune disease that results in a chronic painful synovial joints with morning Stiffness, Swan Neck Deformity, boutonniere deformity and the development of fibrous tissue (pannus) in the synovium.
Definition
Rheumatoid Arthritis
Term
Urethritis, Conjunctivitis, Oligoarthritis
Definition
Reiter's Syndrome
Term
Most Common Pathogen for Pneumonia in EtOH Abusers
Definition
Klebsiella
Term
Lachman Test is to test for:
Definition
ACL injury
Term
Negative Prehn's sign indicates no pain relief with lifting the affected testicle. This result suggests what dx?
Definition
Testicular torsion
Term
Positive Prehn's sign indicates there is pain relief with lifting the affected testicle. This result suggests what dx?
Definition
Epididymitis
Term
A connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis affecting 5% of men causing pain, abnormal curvature, erectile dysfunction, indentation, loss of girth and shortening.
Definition
Peyronie's disease
Term
Proteinuria WITH (not w/o) hematuria suggests what dz?
Definition
Nephritic Syndrome
Term
Proteinuria WITHOUT (not w/) hematuria suggests what dz?
Definition
Nephrotic Syndrome
Term
RBC Casts in urine suggest?
Definition
Glomerulonephritis
Term
Transient Vision Loss
Definition
Amaurosis fugax
Term
Flashers and Floaters,
Curtain Over Vision
Definition
Retinal Detachment
Term
Unilateral Acute Headache with Injected Eye and Clear Nasal Discharge
Definition
Cluster Headache
Term
Spaghetti and Meatballs look under microscope:
Definition
Tinea
Term
WBC Casts in Urine
Definition
Pyelonephritis
Term
Muddy Casts
Definition
Renal tubular Necrosis or Acute Tubular Necrosis
Term
Foul, Greasy Stool, Infected Water, No Obvious Blood
Definition
Giardia Lamblia
Term
Smokers with Black Finger Tips
Definition
Thromboagintis Obliterans
Term
Factor 9 deficiency
Definition
Hemophilia B
Term
Neuro event where pt has Locked in Syndrome. What dx? what area is dz?
Definition
Brainstem CVA
Term
Motion of exam Meaning: Turned Out
Definition
Varus
Term
Motion of exam Meaning: Turned in
Definition
Valgus
Term
Continuous Colonic Bleeding Ulcers
Definition
Ulcerative Colitis
Term
Bowel dz with Skips Areas, Fistulas and Apthoid Ulcers
Definition
Crohn's
Term
Whooping Cough bug
Definition
Pertussis
Term
Chocolate Agar medium to grow
Definition
N. gonorrhoeae
Term
Gray Membrane seen in the throat
Definition
Diphtheria
Term
Strawberry Tongue is seen with which dx?
Definition
Strep throat
Term
Trismus
Submental Tenderness
Definition
Ludwig's Angina
Term

Vincent's Angina, "Trench Mouth", Fusobacterium/Treponema and 

 

Tx options

Definition

Acute Necrotizing Ulcerative Gingivitis

 

Bacteria implicated in the condition are Treponema vincentii, Fusobacterium nucleatum, and Prevotella intermedia.

Treatment is by correcting oral hygiene deficiencies, oxygenating mouthwashes, and systemic antibiotic therapy.

Term
Central Obesity, HTN, DM II, Low HDL
Definition
Metabolic Syndrome
Term
Group A Strep, Painful, Well Demarcated "Fiery Red Face"
Definition
Erysipelas
Term
High IgE with Recurrent Staph Furunculosis
Definition
Jobs Syndrome
Term
Fifth's Disease is what virus?
Definition
Parvo B19 virus
Term
Acute or chronic inflammatory arthritis that causes pain in one or more joints and elevated white blood cell count. Elevated Calcium Pyrophosphate is also seen with this.
Definition

 

Calcium Pyrophosphate Arthritis.

also called

Pseudogout or Chondrocalcinosis

Term
Cat Bite bacteria
Definition
pasteurella multocida
Term
Sx: begins as a painless, pruritic papule that appears 1 to 7 days after exposure.
Definition
Anthrax
Bacililus anthracies
Term

Blue Sclera

dx?

Definition

Osteogenesis Imperfecta.

Other signs are brittle bones and deafness.

Term
Roth Spots


Janeway Lesions, Osler's Nodes, Splinter Hemorrhage, Conjunctival, Palatal, Subungual Petechiae
Definition
Infectious Endocarditis
Term
Painless Red Lesions on the Palms and Soles seen in Endocarditis
Definition
Janeway Lesions
Term
Painful, Violaceous, Raised Lesions of the Fingers, Toes, or Feet seen in Endocarditis
Definition
Osler Nodes
Term
Coninuous "Machinery" Murmur at S2 at 2nd LICS
Definition
Patent Ductus Arteriosus
Term
Blood & Thunder Retina, Sudden, Unilateral Blurred or Loss of Vision. dx?
Definition
Central Retinal Vein Occlusion
Term
Defect of Peripheral Vision, Increased cup-to-disc ratio. Dx?
Definition
Open-Angle Glaucoma
Term
Sluggish Pupillary Response, proptosis, decreased EOM
Definition
Orbital Cellulitis
Term
Elevated, yellowish, Conjunctival Mass on Sclera Adjacent to Cornea
Definition
Pinguecula
Term
Fleshy, Triangular Mass which Grows from Nasal Side Toward Cornea
Definition
Pterygium
Term
Temporal Tenderness, Highly Elevated ESR, Permanent Blindness if Untreated. dx?
Definition
Temporal Arteritis
Term
a condition in which the eyes are not properly aligned with each other. Involves a lack of coordination between the extraocular muscles, which prevents bringing the gaze of each eye to the same point in space, hampers proper binocular vision. dx?
Definition
Strabismus
Term
Night Blindness, Xerosis, Bitot's Spots (White Patches on Conjunctivae) dx?
Definition
Vitamin A Deficiency
Term
Ptosis, Miosis and Unilateral Facial Anhidrosis
Definition
Horner's Syndrome
Term
Horizontal Nystagmus with Fast-Paced Beats, Away from Defect dx?
Definition
Peripheral Vertigo
Term
Nonfatigable Vertical Nystagmus
Definition
Central Vertigo
Term
Painless, White Areas on tongue and buccal mucosa seen with Tobacco, Smokers, AIDs, EtOH. Cannot Be Scraped Off
Definition
Leukoplakia
Bx r/o cancer
Term
Most Common Pathogen for CAP in Cystic Fibrosis
Definition
Pseudomonas sp.
Term
Tachypnea, Retractions. RSV most common pathogen
Definition
Acute Bronchiolitis
Term
Most Common Types of Lung Cancer
Definition
85% are Squamous cell carcinoma, adenocarcinoma, or Large cell carcinoma. 10-15% are small cell.
Term
Tumor at Lung Apex
Definition
Pancoast's Tumor
Term
Headache, Plethora (red, flushed face), Dyspnea, Facial edema, Venous distention in the neck and distended veins in the upper chest and arms
Definition
Superior Vena Cava Syndrome
Term
Pink Puffers, Barrel Chested, Weight Loss
Definition
Emphysema-COPD
Term
Blue Bloaters, Pursed-Lip Breathing, Overweight and Cyanotic, Peribronchial and Perivascular Markings
Definition
Chronic Bronchitis-COPD
Term
Decreased FEV1/FVC ratio & FEV1 Decreases with severity
Definition
COPD
Term
Decreased Ratio FEV1/FVC & Increase in FEV1 after bronchodilator therapy
Definition
Asthma
Term
Hypercoagulability, Venous Stasis, Vascular Inflammation or Injury
Definition
Virchow's Triad seen in events leading to Embolisms
Term
Protein Rich Pulmonary Edema, Frothy Pink or Red Sputum, Hx of : Sepsis, Multiple Trauma, or Aspiration of gastric contents
Definition
ARDS
Term
In newborns, Deficiency of Surfactant, "Ground Glass" on x-ray and doming of the diaphragm, Brief stop in breathing (apnea), Decreased urine output, Grunting, Nasal flaring, Rapid breathing
Definition
Infant Resp Distress Synd (IRDS) from Hyaline Membrane Disease
Term
Yellowish or Gray, Scaly and Greasy Looking Papules
Definition
Seborrheic Dermatitis
Term
Leather like, Well-Circumscribed, Highly Pruritic Plaques, Caused by repeated scratching and rubbing of atopic dermatitis
Definition
Lichen Simplex Chronicus
Term
Leather like Thickened Skin with Distinct Borders
Definition
Lichenification
Term
Poxvirus Discrete, Fleshcolored, Waxy Dome-Shaped Umbilcated Papules
Definition
Molluscum Contagiosum
Term
When slight rubbing of the skin results in exfoliation of the outermost layer, forming a blister within minutes
Definition
Nikolsky's Sign. seen in Pemphigus Vulgaris
Term
Fragile Vesicles or Bullae which are Easily Ruptured. Nikolsky's Sign+
Definition
Pemphigus Vulgaris
Term
Severe, deep-seated, recalcitrant folliculitis with surrounding eczema
Definition

Sycosis, an inflammation of hair follicles, especially of the beard area. Usually chronic. 

Can be fungal, bacterial, viral or inflammatory and is usually papulopustual.

Term
Severe form of EM with Mucocutaneous blistering rxn, commonly caused by drug rxn. Sheet-like loss of epidermis, Raised, Flaccid Blisters, Necrotic epidermis
Definition
Stevens-Johnson Syndrome
Term
Life-Threatening Severe form of Stevens-Johnson Syndrome
Definition
toxic epidermal necrolysis (TEN)
Term
Apocrine Gland Disease, Tender Inflammatory Nodules or Abscess Form Lesions NOT related to hair follicles
Definition
Hidradenitis Suppurative
Term
Koilocytotic Squamous Cells, Cauliflower Appearance
Definition
Verrucae (warts)
Term
benign plaque, beige to brown-black, velvety, warty surface that appears "Stuck On"
Definition
Seborrheic Keratosis
Term
Nonhealing, Translucent or Pearly Papule, Surface telangietasias, Central Erosion
Definition
Basal Cell Carinoma
Term
Skin Darkens, Appears Dirty, Thickens, & Velvety
Obesity and Insulin Resistance Common
Definition
Acanthosis Nigricans
Term
Hyperpigmentation associated with Pregnancy, OCPs, and Estrogen. Uniform Color
Definition
Melasma (aka Chloasma)
Term
Painful, Edematous, Very Red, Indurated, Spreading Lesions with a Raised Border.
Group A Strep
Definition
Erysipelas
Term
Nonpainful, Numerous, Pale Pink, Discrete Lesions with projections on a broad base. Smooth or velvety, moist surface
Definition
Condyloma Acuminata
Term
Violaceous or Blue Vesicular or Bullous Rash. Viral-Like Prodrome. Abrupt onset severe pain mimic peritonitis
Definition
Toxic shock syndrome
Term

Neoplastic type of lesion occurring in the proximal 2/3 of the esophagus.

What type of cancer?

Definition
Squamous Cell Carcinoma
Term
Gram- Spiral-Shaped Bacillus
Type B gastritis. Involves antrum and body of stomach, PUD, Gastric adenocarcinoma & G.lymphoma
Definition
Helicobacter Pylori
Term
Urea breath test to identify...
Definition
Helicobacter Pylori
Term
caused by a non–beta islet cell, gastrin-secreting tumor of the pancreas that stimulates the acid-secreting cells of the stomach to maximal activity, with consequent gastrointestinal mucosal ulceration.
Definition
Zollinger-Ellison Syndrome
Term
Where is Virchow's Node
Definition
Left Supraclavicular Lymph Node
Term
Common extranodal site for Non-Hodgkin's Lymphoma
Definition
Stomach - Gastric Lymphoma
Term
Most common cause of SBO
Definition
Adhesions (most common), Hernias, Neoplasm, Crohn's
Term
Most common cause of Large Bowel Obstruction
Definition
Colon Cancer
Term
Progression is Distal to Proximal, Continuous, Mucosal Surface, Tenesmus and Bloody, Pus-Filled Diarrhea, Smoking May Suppress Frequency of Episodes
Definition
Ulcerative Colitis
Term
Most common cause of chronic or recurrent abdominal pain in the US. Pain worse with food and typically relieved by defecation. Postprandial Urgency
Definition
IBS
Term
Most common cause of Intussesception in: 1) Children 2) Adults
Definition
1) Post Viral Infection
2) Neoplasm (therefore barium enema should not be used, CT is best
Term
Colicky Pain, Currant Jelly Stools, "Sausage-Like" Mass on Palpation
Definition
Intussesception
Term
Systemic Immune Response 15-20 days after exposure to Strep Pharyngitis, Peak age 5-15, Jones' Criteria
Definition
Acute Rheumatic Fever
Term
Inhibits Pre-synaptic release of Acetylcholine at NMJ
Definition
Botulism
Term
Vesicular Lesions with Blue-Black Centers that ulcerate and necrose
Definition
Anthrax (Bacillus anthracis)
Term
Massive Diarrhea causing Death From Hypovolemia
Definition
Cholera
Term
Interferes with neurotransmission at spinal synapses of inhibitory neurons causing Uncontrolled spasm and exaggerated reflexes from Puncture Wounds
Definition
Tetanus (Clostridium tetani)
Term
Peyer's Patches. Bacteremia and Pea Soup Diarrhea. Pink papules on trunk that fade with pressure
Definition
Enteric (Typhoid) Fever. caused by Salamonella
Term
1o bug of Dysentery
Definition
Shigella
Term
Colonocopy shows inflamed, engorged mucosa, Punctate Lesions, or Ulcers
Definition
Shigellosis (Dysentery)
Term
Tenacious Gray Membrane which covers tonsils and requires Horse Serum Antitoxin
Definition
Diphtheria
Term
Virus of Mono
Definition
Epstein Bar Virus
Term
Hyperplastic Prickle Cells
Definition
HPV
Term
Skin Warts virus
Definition
HPV 1 & 4
Term
Anogenital Warts virus
Definition
HPV 6 & 11
Term
Cervical Warts virus
Definition
HPV 16 & 18
Term
Hutchinson's Sign. what is it?
Definition
A skin lesion on the tip of the nose precedes the development of ophthalmic herpes zoster.
Term
A skin lesion on the tip of the nose precedes the development of:
Definition
ophthalmic herpes zoster
Term
Illness occurs in immunocompromised or posttransplant patients. Symptoms similar to Mono w/out pharyngitis or respiratory symptoms,"Pizza Pie" Retinitis, Intracytoplasmic Inclusions "Owls' Eyes"
Definition
CMV
Term
Dimorphic Fungus from Soil with Bird or Bat Droppings, "Miliary Infiltrates" and urine antigen assay
Definition
Histoplasmosis
Term
Illness in Immunodeficient Patients.
Encapsulated, Budding Yeast from Soil contaminated by Pigeon Fecies
Definition
Cryptococcus
Term
Most common opportunistic infection in HIV disease
Definition
Pneumocystis jiroveci pneumonia (PCJ) formally P. carnii PCP)
Term
Loosely attached to mucosa, primarily cecum. Lay eggs on perianal skin. Perianal Pruritis, crawling sensation worse at night. Secondary excoriations and impetigo
Definition
Pinworms (enterobiasis)
Term
Gummatous Lesions, Chronic meningitis, Tabes Dorsalis, Argyll Robertson Pupil
Definition
Tertiary Syphilis
Term
Argyll Robertson Pupil seen in which dx?
Definition
neurosyphilis (tertiary syphilis)
Term
Bilateral small pupils that reduce in size when the patient focuses on a near object (they “accommodate”), but do not constrict when exposed to bright light (they do not “react” to light).
Definition
Argyll Robertson Pupil seen in neurosyphilis (tertiary syphilis)
Term
Abnormal Skin of Mucous Membranes, Nasal Discharge (Snuffles), hepatosplenomegaly. Anemia, Osteochondritis. If untreated: interstitial keratitis, Hutchinson's Teeth, Saddle Nose, Deafness, and CNS abnormalities
Definition
Congenital Syphilis
Term
Hutchinson's Teeth, Saddle Nose, Deafness, and CNS abnormalities are seen in which dz?
Definition
Congenital Syphilis
Term
What is a Jarisch-Herxheimer Reaction
Definition
fever, toxic state, occurs with sudden massive destruction of spirochetes (syphilis). To prevent: Give pyretics during first 24h of treatment
Term
Facial Flushing and Conjunctival Injection, Faint Macules, maculopapules, petechiae develop
Wrist and ankles first then spread to extremities and trunk
From wood tick bite
CSF: Pleocytosis and Hypoclycorrhachia
Definition
Rocky Mountain Spotted fever
Term
Elevated BP associated with papilledema and other encephalopathy or neuropathy. May progress to Renal Failure
Definition
Malignant Hypertension
Term
Common BP medication which must be avoided in bilateral renal artery stenosis:
Definition
ACE-I, because it vasoconstricts the renal efferent areterioles causing reduced GFR
Term
Parasternal Lift, Enlarged Apical Impulse, Diminished 1st Heart Sound, S3 Gallop
Definition
CHF
Term
Post-MI Syndrome of Pericarditis, Fever, Leukocytosis, Pericardial or Pleural effusion, Usually 1-2 weeks post-MI
Definition
Dressler's Syndrome
Term
Pressure Ulcer from Fecal mass in fecal impaction pressing against colon wall
Definition
Stercoral Ulcer
Term
Patient is supine and attempts to raise the leg against resistance. Pain in RLQ is evaluated with this sign:
Definition
Psoas sign
Tests for Appendicitis
Term
Patient is supine and attempts to flex and internally rotate right hip with knee bent. Pain in RLQ is evaluated with this sign:
Definition
Obturator sign
Tests for Appendicitis
Term
Pancreatic Calcification, Steatorrhea and DM is the classic traiad for identification of:
Definition
Chronic Pancreatitis
Term
Courvoisier's Law: an enlarged gallbladder which is nontender and accompanied with mild jaundice is likely what dx:
Definition
Malignancy of Pancreas or GB and is unlikely caused by Gallstones
Term
Chronic thickening of bile duct walls, 80% association with IBD, esp UC.
Strongly assoicated with Cholangiocarcinoma, also Pancreatic and Colorectal Carcinoma. Jaundice and Pruritis most common sx. Liver Transplant only tx with known survival benefit
Definition
Primary Sclerosing Cholangitis (PSC)
Term
It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).
Definition
HBcAg
Hepatitis B core antigen
Term
Fatigue, malaise, anorexia, nausea, Tea-Colored Urine
Definition
Viral Hepatitis
Term
Tx for Hep C, before 2013
Definition
Pegylated Interferon Alpha-2a or 2b and Ribavirin
Term
Sofosbuvir (Sovaldi) and Simeprevir (Olysio) were approved by the FDA to treat what chronic viral infection. They are effective (curative) in 80%-95% of patients. They work by blocking a protein needed by the virus to multiply. What is the dz?
Definition
Hep C tx after 2013
Term
Passage of intestine through external ring at Hesselbach's Triangle. Occurs medial to the inferior epigastric vessels when abdominal contents herniate through a weak spot in the fascia of the posterior wall of the inguinal canal.
Definition
Direct Inguinal Hernia
Term
Occurs when abdominal contents protrude through the deep inguinal ring, lateral to the inferior epigastric vessels
Most common type
Definition
Indirect Inguinal Hernia
Term
Congenital abnormality Caused by absence of Meissner's and Auerbach's Autonomic Plexuses Enervating the Bowel Wall. Sx: constipation or Obstipation, Vomiting, and Failure to Thrive
Definition
Hirschsprung's Disease aka Congenital Megacolon
Term
Deficiency Causes:Megaloblastic Anemia, Poor Nerve Function
Definition
B12 (cobalamin)
Term
Deficiency Causes: Megaloblastic Anemia, Sore tongue, Diarrhea, Mental disorders
Definition

Folate

Vitamin B9

Term
Deficiency Causes: Heachache, Seizures. Flaky Skin, Sore Tongue
Definition
B6 (pyridoxine)
Term
Deficiency Causes: Dermatitis, Tongue Pain, Anemia, Depression
Definition
Biotin
Term
Deficiency Causes: Rickets, Osteomalacia
Definition
Vitamin D
Term
Toxicity of this causes: Hypercalcemia, Kidney Stones, Soft-Tissue Deposits
Definition
Vitamin D
Term
Rare autosomal recessive inability to metabolize phenylalanine. Can cause mental retardation and movement disorders if undiagnosed by age 3
Definition
Phenylketonuria
Term
Abrupt, Intense Abdominal Pain, Out of proportion to PE findings
Definition
Acute Mesenteric Arterial Occlusion (ischemia)
Term
Patients with Long QT syndrome should avoid this class of Antibiotics
Definition
Macrolides and some fluorquinolones
Term
14 y/o presents with fever, myalgias, arthralgias, carditis, and polyarthritis, ASO titer +
Tx of choice for fever and arthralgias is?
Definition
Salicylates (ASA) drug of choice in Rheumatic Fever
Term
pulsus paradoxus - the exaggerated decline of BP during inspiration is seen with what dx?
Definition
tamponade, constrictive pericarditis, massive PE
Term
pulsus alterans - a physical finding with arterial pulse waveform showing alternating strong and weak beats.It is almost always indicative of:
Definition
left ventricular systolic impairment
Term
Hyperventilation with deep, rapid sighing is what type of breathing and seen with what dx?
Definition
Kussmaul Breathing seen in metabolic acidosis
Term
Biot breathing is what?
Definition
an abnormal pattern of breathing characterized by groups of quick, shallow inspirations followed by regular or irregular periods of apnea. Seen with Pons damage. poor prognosis
Term
scotoma - areas of partial blindness in field of vision is seen with which dx?
Definition
glaucoma
Term
acoustic neurinoma, labyrithitis and Menieres dz are all causes of this sx:
Definition
tinnitus
Term
Kopliks spots - small red spots with bluish-white centers are seen with which dx?
Definition
Measles
Term
Janeway spots/lesions - tiny red lesions on palms and soles - are seen with which dx?
Definition
infective endocarditis
Term
Roth Spots - subrentinal hemorrhages with pale centers - are seen with which dx?
Definition
infective endocarditis
Term
Oslers Nodes - tense raised nodules on fingers and toes - are seen with which dx?
Definition
infective endocarditis
Term
Heberden's nodes - painless bony enlargement of the DIP - are seen with which dx?
Definition
osteoarthritis
Term
Virchow's node - palpable supraclavicular lymph node - is seen with which dx?
Definition
stomach CA
Term
Cullen's sign - hemorrhagic patches near umbilicus - are seen with which dx?
Definition
intra-abdominal bleeding
Term
Turners sign - hemorrhagic patches at flanks - are seen with which dx?
Definition
intra-abdominal bleeding
Term
spider angioma - telangiectasia on face and neck - are seen with which dx?
Definition
liver cirrhosis
Term
asterixis - flapping tremors - involving the wrist joints and fingers - are seen with which dx?
Definition
hallmark of hepatic encephalopathy
Term
decorticate posturing is indicative of:
Definition
damage to corticospinal tract
Term
decerebrate posturing is indicative of:
Definition
damage to upper brainstem
Term
Common lab value seen in Addisons and with ACE inhibitors
Definition
hyperkalemia
Term
ABG with pH up, paCo2 up is what Acid Base result?
Definition
Metabolic alkalosis
Term
ABG with pH up, paCo2 down is what Acid Base result?
Definition
Respiratory alkalosis
Term
ABG with pH down, paCo2 down is what Acid Base result?
Definition
Metabolic acidosis
Term
ABG with pH down, paCo2 up is what Acid Base result?
Definition
Respiratory acidosis
Term
water bottle sign on CXR is seen on which dx?
Definition
pericardial effusion
Term
honeycombing on CXR is seen on which dx?
Definition
end stage lung fibrosis
Term
lead pipe sign on abdominal XR is seen on which dx?
Definition
ulcerative colitis
Term
cobble-stoning is seen on abd x-ray with which dx?
Definition
crohn's
Term
napkin ring seen in the right abd on x-ray indicates:
Definition
right colon ca
Term
apple core seen in the left abd on x-ray indicates:
Definition
left side colon ca
Term
EKG with prolonged P-R, shortened Q-T and scooping depressed ST segment indicates what condition?
Definition
digitalis toxicity
Term
S3 and S4 gallop is seen with what dz? Hint Galloping horses have big hearts.
Definition
CHF
Term
Total cholesterol calculation(s)
Definition
TC = HDL + LDL + VLDL
TC = HDL + LDL + (Triglycerides/5)
Term
Cholesterol results and how they identify risk for CAD
Definition
TC > 240 increased risk for CAD
LDL > 160 increased risk for CAD
HDL < 35 increased risk for CAD
HDL > 60 protective against CAD
LDL/HDL rastio < 4 desirable
Term
decreased serum ferritin indicates
Definition
iron deficiency anemia
Term
Iron TIBC (transferrin) lab increased indicates:
Definition
blood loss
iron deficiency anemia
Oral contraceptives
Term
Iron TIBC (transferrin) lab decreased indicates:
Definition
anemia of chronic dz
cirrhosis
nephrotic syndrome
Term
if transferrin saturation is <15%, this indicates:
Definition
iron deficiency anemia
Term
cotton wool scull on xray indicates:
Definition
Paget's
Term
punched out radiolucent areas on a scull xray indicate:
Definition
multiple myoloma
Term
flash or rapid pulmonary edema likely cause:
Definition
papillary muscle rupture
Term
Occurs several weeks after MI
pericardial and pleural effusions
fever, joint pains
tends to recur
Definition
Dressler's syndroma
Term
most common viruses which cause pericarditis:
Definition
Coxsackie A and B, also ECHO virus
Term
Classes I through IV CHF designation. What are the Classes defined?
Definition
Class I - no sx with nl activity
Class II - sx with normal activity
Class III - sx with minimal activity
Class IV - sx at rest
Term
vasospasms of finger arteries
cyanosis followed by hyperemia (red)
precipitated by cold or emotional upset
Definition
Raynaud's phenomenon
Term
stable tx for WPW
Definition
quinidine to prolong A-V time
Term
Bacteria most common for infective endocarditis (General population and drug users)
Definition
General population - strep viridans
Drug users - staph aureus
Term
Pleural effusions with higher protein on aspirate, will happen in more acute setting. type and causes:
Definition
Type - exudative
Caused by infection, malignancy, PE
Term
Pleural effusions with lower protein on aspirate, will happen in less acute setting. type and causes:
Definition
Type - transudative
Caused by chronic dz: CHF, Nephrotic syndrome and liver failure
Term
non-caseating granulomas
bilateral hilar lymphadenopathy.
dx involves liver, spleen, eyes and skin
Definition
sarcoidosis
Term
non-caseating granulomas
hilar lymphadenopathy.
Ghon complex -calcified peripheral nodule plus calcified hilar lymph node
Definition
1o TB
Term
current jelly sputum indicates which bacteria?
Definition
Klebsiella
Term
Bacteria commin with CF pt pnemonias
Definition
Pseudomonas
Term
fungal pneumonia seen in immunocompromised pts
Definition
PCP - pneumocystis carinii
Term
Lung cancers by location and commonality
SCC -
Adenocarcinoma -
Large Cell -
Small Cell -
Definition
SCC - 35% central
Adenocarcinoma - 35% peripheral
Large Cell - 15% central/peripheral
Small Cell - 15%, central, poorest prognosis
Term
Lung CA staging (different than others)
Definition
Stage I - 3cm or less tumor
Stage II - >3cm or invades broncus or visceral pleura
Stage III - invades chest wall or diaphragm.
Stage IV invades mediastinum or trachea or esophagus, or veterbral body or shows pleural effusion
Term
type of CA from Barrets
Definition
adenocarcinoma
Term
Earliest lab indicator of acute Hepatitis B infection
Definition
anti-HBc (C-you have the dz)
Term
Lab indicator of Hepatitis B immunity after infection or vaccination
Definition
anti-HBs (Your Hepatitis is SSStable)
Term
Duke stages A through D for colorectal ca and 5yr survival for each
Definition
Duke A - Limited to mucosa. 5yr survival 95%
Duke B - extends to serosa. 5 yr survival 65%
Duke C - extends to regional Lymph nodes. 5 yr survival 30%
Duke D - distant Mets 5y survival 5%
Term
RBC casts in UA indicate:
Definition
acute glomerulonephritis
Term
Azotemia (azot, "nitrogen" + -emia, "blood condition") is characterized by abnormally high levels of nitrogen-containing compounds. it is caused by:
Definition
insufficient filtering of blood by the kidneys. Can lead to uremia
Term

Kidney labs of azotemia

(renal insufficiency/failure):

Definition

Bun >20, Creatinine >1.5

in Azotemia, nitrogen is elevated in urea and creatinine. Can lead to uremia.

Term
ARF has 3 types. prerenal, renal and post renal. what are the 1o causes of each?
Definition
prerenal - low cardiac output
renal - acute kidney dz's
postrenal - obstruction (stone)
Term
dirty brown granular casts in urine indicate:
Definition
acute tubular necrosis
Term
Nephritic vs. Nephrotic syndromes
Definition
Nephritic - RBC and hematuria
Nephrotic - proteins and lipids in urine. systemic edema.
Term
compare epididymitis vs. torsion with pain change with elevation of teste:
Definition
epididymitis - pain relieved with teste elevation.
torsion - no change in pain with elevated
Term
AIDS is dx with positive HIV test and what other requirement(s)
Definition
CD4 count <200 or
CD4 count <14% or
opportunistic infection.
Term
rash of toxic shock
Definition
erythroderma (sunburn skin) on hands and feet of young females.
Term
thalassemia anemia is a microcytic anemia which has particular identifiable cells. what are they?
Definition
target cells
Term
burr cells are seen in which normocytic anemia dz?
Definition
chronic renal failure
Term
Dz with Reed-Sternberg cells. They are usually derived from B lymphocytes. they are the hallmark of:
Definition
Hodgkin's Dz
Term
Considering Hodgkin's dz vs. non-Hodgkin's lymphoma, which form has a Leukemia component?
Definition
Non-Hodgkin's Lymphoma
Term
palliative vs cure treatments for CML
Definition
Palliative = continuous hydroxyurea and alpha interferon
Cure = Bone marrow transplant
Term
treatments for CLL
Definition
most don't require specific therapy, prednisone for fatigue and LAD
Term
if FSH and LH hormones are low, this indicates
Definition
early pituitary failure
Term
weakness, malaise, nausea and vomiting with hyperpigmentation of skin:
Definition
Addison's dz
Term
After long term glucocorticoid use, moon face, buffalo hump. dx?
Definition
Cushings syndrome
Term
primary corticoadrenal insufficiency:
Definition
Addisons
Term
Dexamethasone suppression test to identify:
Definition
Cushings syndrome
Failure to suppress confirms Cushings
Term
An autoimmune disease in which the thyroid gland is attacked by a variety of cell- and antibody-mediated immune processes
Definition
Hashimoto's thyroiditis
Term
hyperthyroid, 1o cause
Definition
Graves dz
Term
hypothyroid, 1o cause
Definition
Hashimoto's thyroiditis
Term
resting tremors and pill rolling
Definition
Parkinsons
Term
Huntington's chorea is associated to a defect in which chromosome?
Definition
Chromosome 4
Term
a systemic polyneuropathy following minor infections, immunizations or surgical procedures with sx of symetrical extremity weakness starting distally but settling in proximal muscles. Preceding infections with Campylobacter jejuni
Definition
Guillain-Barre syndrome
Term
type of primary intracranial neoplasms are of what type?
Definition
appx half of all are gliomas, the remaining half are meningiomas, pituitary adenomas, neurofibromas and others.
Term
hordeolum vs. chalazion
Definition
hordeolum (stye):a red, painful sore lump near the edge of the eyelid, caused by an infected eyelash follicle.
Chalazion: when an oil-producing gland in the eyelid called the meibomian gland becomes enlarged and the gland opening becomes clogged with oil and tend to develop farther from the edge of the eyelid than styes. Often larger than stye, a chalazia usually isn't painful.
Term
severe headache with nasal congestion and lacrimal dc, no aura, no facial pain
Definition
Cluster HA
Term
in a funduscopic exam, focusing on a distant object serves what purpose?
Definition
keeps eye still and dilates pupil from distant focusing
Term
pronator drift is associated with which area dysfunction?
Definition
vestibular dysfxn
Term
Having the pt say ahhh and looking at the uvula's central or deviated movement evaluates which CN?
Definition
CN-X
abnl test result, the uvula deviates toward deficit
Term
Touch sensation may be preserved despite cord damage because?
Definition
fibers travel on both sides of cord
Term
The most sever form of MS is:
Definition
Relapsing/progressive.
Because, these pts have chronic sx with occasional and worsening flairs and little remissions.
Term
Athetosis: a condition in which abnormal muscle contractions cause involuntary spastic or writhing movements. Is seen commonly in which dz?
Definition
Cerebral Palsy
Term
3 cardinal motor signs of Parkinsons dz are:
Definition
tremor (resting or postural), bradykinesia, and rigidity
Term
Which infection is sometimes the cause of Bells Palsy?
Definition
Borrelia burgdorferi (lyme dz and some OM can cause this dz)
Term
increased IOP can result in which funduscopic finding?
Definition
increased cup, >1/2 disc diameter
Term
Painful red eyes and decreased vision with noted preauricular LAD. These findings suggest:
Definition
herpes karatitis
Term
A nodule, usually in the nasal side of conjunctiva, with mild discoloration:
Definition
pinguecula
Term
Yellow red lesion in the nasal sclera which can interfere with vision:
Definition
pterygium
Term
pinguecula vs. pterygium
Definition
Pinguecula is a discolored nodule usually in the nasal conjunctiva.. Pterygium is a vascularized lesion usually on the nasal conjunctiva that may encroach on the cornea affecting vision.
Term
Polymorphonuclear leukocytes with intracellular gram negative diplococci are presumptive of which bacteria?
Definition
gonococcal infection
Term
Systemic and topical steriods have what affect on intraocular pressure?
Definition
They increase IOP.
Term
Common useful meds for tx of glaucoma:
Definition
Cholinergics (Pilocarpine),, anticholinesterases and sympathomimetics
Term
Action of Pilocarpine in glaucoma tx:
Definition
They facilitate the outflow of aqueous by contraction of the ciliary body.
Term
The optic tract is located where?
Definition
After the cerebellum and before the optic chiasm. includes left and right vision nerves
Term
The right optic nerve is located where and what areas of vision are the affected by the nerves?
Definition
After the optic chiasm and before the eye. includes right medial and central vision nerve intervention and left nerve intervention for lateral right eye vision.
Term
Red hyperplastic lesions on the oral mucosa is an indicator for:
Definition
premalignancy
Term
Noise, drug induced loss, acousitc neuromas, Menieres dz, presbycusis and infection cause what type of hearing loss?
Definition
sensorineural hearing loss
Term
otosclerosis, exostosis and glomus tumors cause what type of hearing loss.
Definition
conductive hearing loss
Term
A positive Weber test refers more sound to which ear?
Definition
The affected hearing loss ear.
A normal Weber test has equal sounds in both ears.
Term
Common Acute OM bacterias:
Definition
S. pneumoniae, H. influenzae, M. catarrhalis, S. epidermis
Term
Common chronic OM bacterias:
Definition
Pseudomonas and enteric gm negatives
Term
An air bone gap on audiogram is consistent with:
Definition
conductive hearing loss
Term
Pt's with normal hearing or sensorineural hearing loss will have what air-bone gap on an audiogram?
Definition
no air-bone gap
Term
two or more weeks of hoarseness w/o other signs of infection indicates:
Definition
Laryngeal carcinoma
Term
sensorineural hearing loss may result in pathology from where?
Definition
Cochlea
Term
Pathology from the TM, ear canal, malleus and ossicle chain cause what type of hearing loss?
Definition
conductive hearing loss
Term
possible cause of chronic or recurrent nasal congestion:
Definition
Chronic sinusitis, GERD, Sleep apnea, nasal polyps, Hypothyroid, Sarcoidosis, pregnancy as well as the usual allergies, URIs and abuse of nose drops
Term
Edema, rubor on legs with dependency is associated with:
Definition
arterial insufficiency
Term
Edema, cyanosis with dependency is associated with:
Definition
venous insufficiency
Term
Lack of plasma protein (albumin) decreases colloid osmotic pressure in vessels causing:
Definition
dependent edema
Term
pigmentation of the skin with noted edema is a result of what chronic condition?
Definition
chronic venous insuffieciency.
Term
Atherosclerosis forms on what portion of the arteries?
Definition
The Tunica (layer) Intima (inner)
Term
[image]
what does this show?
Definition
cotton wool spots
Term
[image]
what does this show?
Definition
macular degeneration
Term
[image]
What does this show and what dz?
Definition
Ground glass as seen in Sarcoidosis
Term
[image]
What does this show and what dz?
Definition
pericardial effusion
Term
[image]
What does this show and what dz?
Definition
tuberculosis
Term
Painful straining during a bowel movement, defines:
Definition
Tenesmus
Term
Fecundity is multiparity. How does this affect risk of cholecystitis?
Definition
It increases risk (5 F's)
Term
What is Roving's sign:
Definition
Referred rebound tenderness. ex: pain in RLQ after attempting rebound tenderness in LLQ
Term
pink, purple striae seen on abdominal inspection indicates:
Definition
Cushing's syndrome
Term
Borborygmi is:
Definition
stomach growling sounds
Term
Are anticholinergic drugs a good treatment for acute pancreatitis?
Definition
No. Contraindicated. Tx should include: Fluids, NPO, pain control, NG suction.
Term
Sudden, steady RUQ or epigastric pain that is worst within 1 hour of onset... dx?
Definition
Biliary colic (biliary colic is steady pain)
Term
Medical therapy (not surgical) for symptomatic gallstone therapy:
Definition
Bile acid dissolusion meds for surgical refusals or those too sick for surgery.
Term
Where does pancreatic ca mets?
Definition
Nearby organs. Most Pancreatic carcinomas spread by direct contact.
Term
1o medicine to treat UC
Definition
Azulfidine (sulfasalazine)
Term
The definition of "guarding" during abdominal exam:
Definition
involuntary spasm of muscles overlying an inflamed organ,
Term
medication helpful with hepatic encephalopathy
Definition
lactulose (lowers blood ammonia by trapping in the GI tract
Term
MME (mini-mental status exam) is the best tool for evaluating what?
Definition
Psych d/o's
Term
The spinal level which affects the medial ankle:
Definition
L4
Term
Positive cross strait leg raise low back pain suggest:
Definition
cord compression
Term
HLA-B27 elevation is specific for:
Definition
ankylosing spondylitis
Term
The production of multiple autoantibodies is the defining characteristic of which dz?
Definition
SLE Lupus
Term
Treatment of SLE includes:
Definition

Hydroxychloroquine for all patients!

also

NSAIDS, Steroids, antimalarials, cytotoxics, anticoagulants

Term
Tinel's test evaluates which nerves?
Definition
median and ulnar
Term
The best test for evaluating a possible ACL injury:
Definition
Lachman's test best, Anterior drawer, similar to Lachman, but not as accurate.
Term
Apley's test evaluates:
Definition
Shoulder ROM (scratch front and back of opposite shoulder)
Term
Ortolani's click test in infants evaluates for:
Definition
Congenital hip dislocations. Winging out of hips produces a palpable click when positive.
Term
The most common injured ligament in an ankle sprain.
Definition
anterior talofibular
Term

[image]

These target lesions are seen in which dx?

Definition
Erythema Multiforme
Term
Atopy includes which dz's?
Definition
Asthma, hay fever, eczema
Term
Koebner's phenomenon (linear streaks near lesions) are seen with which skin condition?
Definition
Lichen planus
Term
Sepsis is most commonly from what type of bacteria (Gram + or -)
Definition
Gram negative toxins.
Term
Tanner stage for elevation of nipple only is:
Definition
Tanner 1 - Preadolescence
Term

1. Erythema migrans, a flat or slightly raised red lesion that expands over several days, typically with central clearing “bull’s eye”[image]

2. neuro sx, cardiac sx weeks/months after.

3. Arthritis - late stages   

These are the 3 stages of ? 

Definition

 

3 stages of Lyme dz

Term
bacteria of lyme dz
Definition
Borrelia burgdorferi
Term
distended jugular veins on inspiration is what condition and seen in which dx?
Definition
Kussmaul's sign seen in constrictive pericarditis
Term

Opisthotonos What is it?

 

When is this seen?

(3+ dz's)

Definition

A state of severe hyperextension and spasticity in which an individual's head, neck and spinal column enter into a complete "bridging" or "arching" position.

 

Seen in infants with meningeal irritation, tardive dyskinesia, tetany.

Term
Cogwheel rigidity (jerking of arm muscles when passively stretched) is a cardinal sign of which dz?
Definition
Parkinson's dz
Term
Wernickes vs Broca's aphasias
Definition
Wernickes - receptive, no word understanding.
Broca's - expressive, word finding d/o
Term
hallmark of hemolytic anemia (like Sickle cell)
Definition
elevated reticulocytes
Term
Tx for localized Hodgkin's (stage 1,2)
Definition
localized radiation
Term
Tx for dissemenated Hodgkin's (stage 3,4)
Definition
combination chemotherapy
Term
Anemias with elevated bilirubin and LDH. Give examples.
Definition
Hemolytic anemias (malaria, DIC, transfusion rxn, drug use, Sickle Cell)
Term
Ann Arbor system is for staging of which dz's
Definition
Hodgkin's dz and Non Hodgkin's Lymphoma
Term
Erbs palsy. what is it and how does it occur?
Definition
Birth trauma palsy. injury to superior brachial plexus C5 and C6
Term
deer mice dz:
Definition
hantavirus
Term
toxoplasmosis is from:
Definition
cats (feces)
Term
virus - psittacosis is from:
Definition
birds
Term
virus - leptospirosis is from:
Definition
rats, dogs, cats
Term
virus - tularemia is from:
Definition
rabits. also ticks and humans
Term
ancephaly and spinabifida are caused by:
Definition
folate deficiency in early development
Term
Rubeola vs. Rubella
Definition
Rubeola (measles) 3-5 day predrome, Koplik's spots, maculopapular rash
Rubella (german measles)mild predrome, tender lymphadenopathy, NO KOPLIK'S SPOTS
Term
Saber shin is a malformation of the tibia. It presents as a sharp anterior bowing of the tibia. Seen in what dz?
Definition
Syphilis
Term
Hutchinson's teeth, saddle nose and Saber shin is seen with which dz?
Definition
Syphilis
Term
what is the bug which causes croup?
Definition
parinfluenza
Term
Asymptomatic abdominal mass (seen in 2-5 y/o's) arises anywhere w/in the kidney:
Definition
Wilm's tumor
Term
Tx for PDA (patent ductus arteriosus) in the first 2 weeks of life:
Definition
Spontaneous closure of the patent ductus arteriosus (PDA) is common. If significant respiratory distress or impaired systemic oxygen delivery is present, therapy is usually prudent. Intravenous (IV) indomethacin (or the newer preparation of IV ibuprofen) is frequently effective in closing a PDA
Term
Abx for pertussis
Definition
Erythromycin for 7-10 days
Term
Rx for tx of BPH
Definition
5 alpha reductace inhibitors
Term
5 P's of Lichen Planus
Definition
Pruritis, Planar (flat), Polyangular/polygonal, Purple, papular
Term
Neonates with meconium ileuses are more susecptable to which dz's
Definition
Cystic fibrosis
Term
Cotton wool spots on funduscopic exam are c/w which dx's
Definition
HTN, Malignant HTN (also AV nicking seen)
Term
Multiple eye disorders including pain and loss of central vision and swollen optic disk. MRI shows multiple white matter lesions on brain. Dx?
Definition
Optic neuritis (MS dx will usually follow)
Term
CSF with high protein and PSI, >300 polys
Definition
Bacterial Meningitis
Term
CSF with nl protein and PSI, <300 polys
Definition
Viral meningitis
Term
Head bobbing a/w aortic regurg. what is the sign called?
Definition
DeMusset's sign
Term
pulsatile blushing of nail beds associated with aortic regurg. what is this sign called?
Definition
Quineke pulse
Term
Labyrinthitis vs Menieres dz
Definition
Labyrinthitis is temporary (<6mos), Menieres dz is chronic and worsening
Term
[image]
Definition
Glaucoma
Term
Tests for evaluating a child, you are concerned with childhood obesity and its sequela, are?
Definition
LFTs and Lipids
Term
Glyburide and other sulfonylurea drugs have what affects on pt's
Definition
stimulation of insulin production by beta islet cells.
Term
Giant Cell arteritis a.k.a temporal arteritis is diagnosed with what test?
Definition
temporal artery biopsy
Term
AAA risk factors do not apply to women. Why?
Definition
Women have relatively low risk for AAA
Term
Hep-C most common mode of transmission:
Definition
Blood (needle sharing, tattoos etc.). Sex is a mode, but not most common.
Term
Pts are not considered infertal until they have had no success in conceiving in how long?
Definition
1 year
Term
First line drug therapy for hypertrophic cardiomyopathy is:
Definition
Beta Blockers
Term
Tx for Tetanus (lock jaw) includes what plan?
Definition
Abx (flagyl) to tx C-tetani, Immune globulin to neutralize toxin and benzos to control spasms. (steroids are not helpful)
Term
A common side effect of ERCP is what dz?
Definition
Pancreatitis (3-5%)
Term
Pt's with Alzheimer's have found improvement with which drug class?
Definition
Acetylcholinesterase inhibitors
Term
A rubbery prostate is found with which dx?
Definition
BPH
Term
Risk factors for endometriosis:
Definition
delayed child bearing, family hx, shortened menstrual cycles.
Term
Nl dx period for gestational DM:
Definition
at 24-28 weeks
Term
MRI of brain of schizophrenia pt:
Definition
reduced brain volume. sometimes also enlarged lateral and third ventricals.
Term
Glargine and Lantus are both:
Definition
Long acting insulins
Term
Essential tremors are treated with:
Definition
anticonvulsants, such as Primidone
Term
Strabismus - when the eyes are misaligned, can be treated with what topical agent?
Definition
Topical Miotics
Term
Unilateral HA with tearing and rhinorrhea is what dx?
Definition
Cluster HA
Term
Cluster HA immediate tx:
Definition
100% O2
Term
The classic triad of arthritis, conjunctivitis and urethritis are seen in which dx?
Definition
Reiter's syndrome (now called reactive arthritis)
Term
ototoxicity is a side effect of what class of antibiotics?
Definition
aminoglycosides (Gentamicin, Streptomycin, Tobramycin)
Term
A patient is a diabetic if their HbA1c is above:
Definition
6.5%
Term
Sarcoidosis is a granulomatous lung dz. Granulomas produce angiotensin-converting enzyme(ACE). Is elevated ACE diagnostic?
Definition
No. it's nonspecific, but suspicion is high
Term
A pt with latent TB is on Isoniazid for how long?
Definition
6-9 months
Term
acanthosis nigricans is a dark pigment see on which pt's
Definition
diabetics
Term
CXR with hilar node calcifications forming a "cracked egg shell" pattern suggests what dx?
Definition
Silicosis (quarry workers dz)
Term
Levonorgestrel is a medicine implanted in what devices?
Definition
Medicated IUDs
Term
Injuries to the rotator cuff usually involve which muscle?
Definition
Teres minor
Term
Sarcoidosis usually affects what demographic?
Definition
Northern Europeans and African American Adults 20-40 years of age
Term
Placenta previa is present in a higher rate with what previous condition?
Definition
Previous C-section pt's
Term
The pathophysiology of shock:
Definition
inadequate cellular oxygen supply (inadequate tissue perfusion)
Term
Pulmonary trunk has how many arteries and veins going through hylum into each lung?
Definition
2 pulmonary arteries and one pulmonary vein on each side.
Term
Obstructive PFT pattern is seen with which dzs?
Definition
Asthma, Emphysema, Chronic Bronchitis.
Term
Restrictive PFTs are seen with which dzs?
Definition
Neuromuscular and chest wall dzs
Term
Most common type of Thyroid CA
Definition
Papillary
Term
A superficial lower esophageal tear caused by repeated vomiting:
Definition
Mallory-Weiss tear
Term

particularly prevalent among Mediterranean people, this form of anemia can form skeletal abnormalities and result in poor growth.

Definition
Beta Thalassemia
Term

[image]

What muscle is affected by this injury?

Definition
Inferior Rectus
Term

 

Pt with recent trauma and the exam shows a collection of blood in the anterior chamber/

 

dx?

Definition

Hyphema

 

[image]

Term

Pt sts painless, sudden loss of vision in one eye. PMHx HLD, HTN

 

Exam shows retinal hemorrhages in all quadrants and swollen optic disk.

 

dx?

Definition

 

Retinal vein occlusion.

 

Refer to ophthalmology.

Term

74-year-old man with sudden vision loss in his right eye. He has a PMHx: HTN, CAD, and new-onset atrial fibrillation.

Exam+, +carotid bruit, visual acuity is light perception only. Confrontational visual fields reveal a dense scotoma, and a penlight examination shows an afferent pupillary defect.

Dilated funduscopic examination shows retinal whitening with a cherry-red spot in the fovea.  Diagnosis?

Definition

 

Retinal artery occlusion.

 

Refer to ophthalmology.

Term

 

In a patient with amaurosis fugax, what is the most appropriate initial diagnostic study?

Definition

 

1st choice: Carotid ultrasound

 

2nd choice:  MR angiography

Term

 

A painless temporary loss of vision in one or both eyes. Most episodes are the result of stenosis or atherosclerosis of the ipsilateral carotid artery.

Definition

Amaurosis fugax (amaurosis meaning darkening, dark, or obscure, fugax meaning fleeting) is a painless temporary loss of vision in one or both eyes. Most episodes of amaurosis fugax are the result of stenosis or atherosclerosis of the ipsilateral

INTERNAL carotid artery.

Term

Pts with noted noted “enfeeblement of memory” and “concepts formed slowly,” along with the classic three sx:

1. nystagmus,

2. intention tremor, and

3. ataxic dysarthria.

Likely diagnosis?

Definition

 

Charcot's Triad seen early descriptions of patients with Multiple Sclerosis (MS)

Term

45-year-old man with new high cholesterol: LDL cholesterol level of 550 mg/dL. He states that his father and brother had high cholesterol and both died at a young age from a heart attack. He has had some occasional chest pain and abnormalities seen on his EKG. Additionally, you notice that he has well-demarcated yellow deposits around his eyes.

He was taking high dose statin and his LDL at 12 weeks is 350 mg/dL.

What is the next best step in this patient's management?

Definition

Add ezetimibe (Zetia) 10 mg daily.

  • Ezetimibe works by reducing the amount of cholesterol absorbed from the food

Then if still elevated, refer to a lipid specialist for starting on a PCSK9 inhibitor (Repatha). 

Term

Located is just above the cricopharyngeal muscle and causes dysphagia and regurgitation with cough and halitosis, but rarely pain.

 

Definition

Zenker's diverticulum.

Just above the cricopharyngeal muscle and causes dysphagia and regurgitation with cough and halitosis.

 

It is an outpouching of the posterior hypopharynx that can cause regurgitation of undigested food and liquid into the pharynx several hours after eating.

 

Term

Target lesions are the hallmark of this disorder, although they may not always be present.

[image]

Dx?

Definition

Erythema multiforme

  • 90% of erythema multiforme minor is related to HSV.
  • EM can be induced by drugs (e.g., sulfonamides, phenytoin, barbiturates, penicillin, and allopurinol).
  • Half of all cases occur in patients younger than 20 years of age.    Tx: avoid precipitating substances. Severe=steroids
Term

Patients present with fever, photophobia, sore throat, mucosal inflammation, and sore mouth. The cutaneous lesions tend to be concentrated more on the trunk initially. The lesions may be painful or may sting. 

Progression occurs over 4 days: diffuse erythema; morbilliform lesions; necrotic epidermis; wrinkled surfaces; sheetlike loss of epidermis and raised, flaccid blisters (positive Nikolsky sign).

 

Definition

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)

SJS (generally <10% body surface area) is thought to be a severe variant of EM, and TEN (generally >30% body surface area) is thought to be a severe variant of SJS.

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