Term
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Definition
Mylo side
Bi-concave greater area for diffusion
Internal struct- Spectrin= allows flex |
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Term
- What is the Process of Making RBC?
- Where is all this released and why.
- What is key to release Erythropoietin?
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Definition
- Kidneys.. D/t a decrease in blood 02.. goes to bone marrow and make new red blood cells.
- Tissue Hypoxia
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Term
How growing RBC WORK?
Who would be a patient with an increase reticularcyte count?
High retic count = |
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Definition
Immature- Nucleated no hemiglobin no 02
Reticularcyte- ER- tiny 02
Mature- no carry 02
PT with tissue hypoxia or COPD guy-
person who has long term tissu hypoxia |
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Term
How long do RBC's live?
d/t no nucleaus can not reproduce..
Hemaglobin that is left over after RBC dies turns into? |
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Definition
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Term
| What is the Process of Bilirubin |
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Definition
Start out unconjunated= toxic
liver connects it to gluconuride to make conjugated
conjugated = no longer toxic is now excreted in bile
* if liver failure can't do this process stays in body... if to many RBC created d/t crushing injury same thing= bad= puts into vasc space. |
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Term
| What 2 things happen is Hymolysis occurs in vascular space |
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Definition
Hemoglobinema= makes plasma turn red
Hemoglobinuria= make urine cola-colored |
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Term
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Definition
Cytic= size= micro/macro
Chromic= color= normo/hypo- HGB |
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Term
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Definition
We do not have enough blood cell carrying copacity
could be a decrease in RBC or You may have enough that are not working properally.
Focus
working/not working |
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Term
| What are 3 causes of Anemia? |
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Definition
- Blood loss- wont have enough cells
- Deficient RBC- workin/notworking
- Hemolysis- break down of RBC
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Term
Deficient RBC production.
- Iron-defiency
- Megablastic anemia
- Aplastic Anemia
- Chronic disease of Anemias
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Definition
- low dietary iron intake
- Increase MCV- Large RBC- dont work well
- abnormal stem cells- d/t bone marrow
- Chronic illness
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Term
| What are causes of Megaloblastic Anemia? |
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Definition
- Vit B12- & Folic acid deficiency-These make RBC
- Pernicious Anemia- Lack intrinsic factor from prietal cells of stomach-we need intrinsic factor to absorb b12
Replace b12 Iv best route |
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Term
| If my RBC are decreased what will i look like? |
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Definition
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Term
| If my 02 is decreased how will this effect my body? |
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Definition
- Tissue Hypoxia- Muscle weakness, brain fanting, heart anginia
- Generalized adaption syndrome/compensate- Vasocontriction-increased hr
- Kidneys release Erythropoietien- bone marrow produce more RBC, Bone marrow exspansion= bone pain
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Term
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Definition
Problem with Break down of RBC
- HGbemia- HG in blood
- Iron retention
- decreased 02 transport
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Term
| What you have to much hemoglobin and Iron what does it cause |
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Definition
| Hereditary Sperocytosis- Spectrin deficiency- cells fold on itself loss of cell membrain |
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Term
| 2 common types of Hemolytic Anemia- which is do to too much HG |
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Definition
- Sickle cell Anemia
- Thalasemia
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Term
| What causes Sickle Cell Anemia? |
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Definition
- Mutation in beta chains of HG
- Deoxygentated causes this and chain links together and look"sickle"
- tissue ishemia begins when vessels are occluded
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Term
| Problem With Sickle Cell Anemia |
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Definition
- Sickle cells Block Capillaries- patient is likely to have blood clots
- Jaundice
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Term
| What happens during Hemolysis? (hemolitic anemia) |
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Definition
Decreased RBC-went through this earlier
Hemoglobin Released- |
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Term
| What happens when hemoglobin is released into blood? |
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Definition
- Hemoglobinuria- Dark URINE
- WBC in spleen and liver turn hemoglobin into bilirubin=spleen liver enlarge=jandice
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