Shared Flashcard Set

Details

Oral Pathology
Soft Tissue Lesions
134
Pathology
Graduate
01/25/2010

Additional Pathology Flashcards

 


 

Cards

Term
What is one of the most frequently encountered abnormalities of oral mucosa?
Definition
Reactive lesions
Term
What are reactive lesions?
Definition
  • Fibrous hyperplasia
  • Over production of collagen with minimal vascularity
  • Not a neoplasm
Term
What is one of the most common lesions in the oral cavity?
Definition
Irritation fibroma
Term
What is another name for irritation fibroma?
Definition
Traumatic fibroma
Term
What is irritation fibroma?
Definition
Dense collagenous tissue with minimal inflammatory cells
Term
Irritation fibroma may grow up to how many centimeters?
Definition
1 to 2 cm
Term
What are other clinical features of irritation fibroma?
Definition
  • Sessile
  • Asymptomatic
  • Slow growing up to 3 years or longer
  • Usually pink but may be leukoplakic due to chronic irritation
Term
How do you treat irritation fibroma?
Definition
  • Excisional biopsy
  • Rarely recurs
Term
What is another name for epulis fissuratum?
Definition
  • Denture induced or inflammatory fibrous hyperplasia
  • Denture epulis
Term
What causes epulis fissuratum?
Definition
Slow irritation by flange of loose denture on the gingiva
Term
Epulis fissuratum is more commonly located where?
Definition
Anterior and facial aspect of ridge
Term
What are other clinical features of epulis fissuratum?
Definition
  • Long single or multiple folds of dense connective tissue in vestibule
  • Asymptomatic
  • Not inflamed but may be ulcerated

 

Term
A similar lesion on hard palate beneath maxillary denture is called?
Definition
  • Fibroepithelial polyp
  • Or leaf like denture fibroma
Term
Giant cell fibroma occurs in what age group?
Definition
First three decades of life
Term
Giant cell fibroma clinically appears as what due to rough surface?
Definition
Squamous fibroma
Term
Giant cell fibroma occurs on the gingiva in what percentage of cases?
Definition
50 percent
Term
Giant cell fibroma also occurs where?
Definition
  • Twice as often on the mandibular gingiva
  • Tongue and palate
Term
What are other clinical features of giant cell fibroma?
Definition
  • Asymptomatic
  • Sessile or pedunculated
  • Not associated with irritation
Term
What do you differentiate giant cell fibroma?
Definition
  • Vascular fibrous tissue
  • Large stellate fibroblasts
  • Thin squamous epithelium but rete ridges may be elongated
Term
What is another name for papillary hyperplasia?
Definition
  • Inflammatory papillary hyperplasia
  • Palatal papillomatosis
Term
What causes papillary hyperplasia?
Definition
  • Ill fitting dentures
  • Chronic atrophic candidiasis
  • Poor hygiene
Term
Papillary hyperplasia due to dentures worn 24 hours a day occurs in what percentage?
Definition
20 percent
Term
What also causes papillary hyperplasia if worn 24 hours a day?
Definition
Flippers
Term
Papillary hyperplasia usually occurs where?
Definition
On hard palate beneath denture
Term
Papillary hyperplasia may extend onto where?
Definition
Alveolar mucosa
Term
What are other clinical features of papillary hyperplasia?
Definition
  • Edematous pebbly surface often red
  • May be inflamed
  • Usually asymptomatic
Term
What are histologic features of papillary hyperplasia?
Definition
  • Orthokeratotic or parakeratotic squamous epithelium
  • With connective tissue core
Term
What is another name for pyogenic granuloma?
Definition
Pregnancy tumor
Term
What size is giant cell fibroma?
Definition
Usually less than 1 cm
Term
What causes pyogenic granuloma?
Definition
  • Response to irritation
  • Maybe calculus
  • Pregnancy
  • Poor oral hygiene
Term
What percentage is pyogenic granuloma commonly encountered in pregnancy?
Definition
1 percent
Term
Pyogenic granuloma occurs in what age group?
Definition
  • Any age
  • More common in children and young adults
Term
Pyogenic granuloma often occurs where?
Definition
  • Interdental gingiva
  • But develops rapidly to any area of body
Term
What are other clinical features of pyogenic granuloma?
Definition
  • Red and pedunculated granulation tissue
  • Bleeds easily
  • Often ulcerated but painless
Term
How do you treat pyogenic granuloma?
Definition
  • Excise to periodontal membrane
  • High rate of recurrence if not completely removed
Term
Pyogenic granuloma may assume fibrous appearance as what if not treated?
Definition
Peripheral fibroma or fibroma
Term
Peripheral giant cell tumor only occurs where?
Definition
Gingiva
Term
Peripheral giant cell tumor may resemble what?
Definition
Pyogenic granuloma
Term
What size is peripheral giant cell tumor?
Definition
  • Varies widely
  • Up to 2.5 centimeters
Term
Peripheral giant cell tumor occurs at what age?
Definition
Around 30
Term
Peripheral giant cell tumor is twice as common in which sex?
Definition
Females
Term
What causes peripheral giant cell tumor?
Definition
  • Trauma or irritation
  • Same as pyogenic granuloma
Term
How do you treat peripheral giant cell tumor?
Definition
Excise to periodontal membrane
Term
What are other clinical features of peripheral giant cell tumor?
Definition
  • Pedunculated or sessile
  • May ulcerate
  • More aggressive
  • Painless
Term
What are histological features of peripheral giant cell tumor?
Definition
  • Fibroblasts with multinucleated giant cells
  • Hemorrhage
  • Possibly inflammatory cells
Term
What is another name for peripheral giant cell granuloma?
Definition
Peripheral giant cell tumor
Term
What color is peripheral giant cell tumor?
Definition
  • Dark and red usually
  • Or blue purple
  • But may be mucosa color
Term
What is another name for peripheral fibroma?
Definition
Peripheral ossifying fibroma
Term
Peripheral fibroma is more common in what age group?
Definition
Young adults and children
Term
Peripheral fibroma is twice as common in which sex?
Definition
Females
Term
Peripheral fibroma only occurs where?
Definition
Gingiva usually anterior to molar region
Term
What size is peripheral fibroma?
Definition
Usually less than 2 cm
Term
What causes peripheral fibroma?
Definition
  • Irritation
  • Odontogenic in origin
Term
What are histological features of peripheral fibroma?
Definition
  • Very cellular like fibroma
  • May have calcification or ossification
Term
How do you differentiate peripheral fibroma?
Definition
Biopsy
Term
What are other clinical features of peripheral fibroma?
Definition
  • Slow growing
  • Firm
  • Color of normal mucosa
  • Nodular, sessile or pedunculated
Term
What is epulis granulomatosa?
Definition
Proliferation of granulation tissue out of recent extraction site or socket
Term
Epulis granulomatosa may mimic what?
Definition
Pyogenic granuloma
Term
Epulis granulomatosa occasionally masquerades as what?
Definition
Metastatic carcinomas
Term
What are other clinical features of epulis granulomatosa?
Definition
  • Painless
  • Bleeds easily
Term
What causes epulis granulomatosa?
Definition
  • Calculus
  • Tooth fragments
  • Bony sequestra in socket
Term
What are neoplasms?
Definition
  • Tumors
  • Unrestricted new growth
  • Even without stimuli
Term
What is the malignant counterpart to lipoma?
Definition
Liposarcoma
Term
What is lipoma?
Definition
Tumor of adipose tissue
Term
Lipoma commonly occurs where?
Definition
  • Often multiple on other parts of body
  • Especially neck
Term
What is one of the most common soft tissue tumors?
Definition
Lipoma
Term
Lipoma occurs more commonly in what oral area?
Definition
Buccal mucosa
Term
Lipoma occurs at what age?
Definition
30+ years
Term
What causes lipoma?
Definition
  • Possible reaction of fat to trauma
  • Benign neoplasm of fat
Term
What are other clinical features of lipoma?
Definition
  • Slow growing
  • Will not decrease in size if patient loses weight
  • Yellowish
  • Often pedunculated
  • Blood vessels visible on surface
Term
How do you differentiate lipoma?
Definition
  • Fibroma if superficial
  • Cyst if deep
  • Salivary gland neoplasm
Term
What is another name for neurolemmoma?
Definition
Schwannoma
Term
What percentage of neurolemmoma occurs in the head and neck region?
Definition
Nearly 25 to 50 percent
Term
Neurolemmoma occurs in what most common intraoral site?
Definition
Tongue
Term
Neurolemmoma also occurs where?
Definition
Bone usually mandible
Term
Neurolemmoma occurs at what age?
Definition
Any age
Term
What are other clinical features of neurolemmoma?
Definition
  • Uncommon nodular mass
  • Painless
  • Usually slow growing
  • Like fibroma
Term
What causes neurolemmoma?
Definition
Tumor of sheath of schwann
Term
What are histological features of neurolemmoma?
Definition
  • Antoni A and B type tissue
  • Well encapsulated verocay bodies
Term
What is another name for neurofibroma?
Definition
  • Multiple neurofibromatosis
  • Von recklinghausen's disease of skin
Term
Neurofibroma occurs where?
Definition
  • Skin most common site
  • Oral mucosa
Term
Neurofibroma of the oral cavity most commonly occurs?
Definition
  • Buccal mucosa
  • Palate and tongue
Term
What is central neurofibroma?
Definition
Neurofibroma may be located within the jaws
Term
Neurofibroma may cause what?
Definition
Macroglossia
Term
What is elephantiasis neuromatosa?
Definition
Small to large nodules to baggy pendulous masses of neurofibroma
Term
What causes neurofibroma?
Definition
  • Arises from schwann cells,
  • Fibroblasts
  • Perineural cells
Term
Neurofibroma is hereditary in what percentage of cases?
Definition
  • Solitary lesions unknown
  • But syndrome inherited in 10 to 20 percent
Term
What is von recklinghausen's disease of skin?
Definition
  • Hereditary form of neurofibroma
  • Multiple lesions
  • Cafe au lait spots
  • Sarcomatous degeneration
Term
Sarcomatous degeneration of neurofibroma occurs in what percentage of cases?
Definition
15 percent
Term
What are histological features of neurofibroma?
Definition
  • Delicate spindle cells
  • Intermingled with neurites
Term
How do you treat neurofibroma?
Definition
No treatment due to sheer number
Term
What is another name for traumatic neuroma?
Definition
Amputation neuroma
Term
What size is amputation neuroma?
Definition
  • Usually few millimeters
  • Less than 0.5 cm
Term
Amputation neuroma is most commonly located where?
Definition
Mental nerve
Term
Amputation neuroma is also located?
Definition
  • Tongue and lower lip
  • Bone
Term
Amputation neuroma occurs in what age group?
Definition
Usually middle aged adults
Term
What causes amputation neuroma?
Definition
  • Traumatic injury
  • Often after tooth extraction
Term
What are histological features of amputation neuroma?
Definition
Mass of irregular neurofibrils and schwann cells
Term
What are other clinical features of amputation neuroma?
Definition
  • Reactive lesion of nerve
  • Usually appears as small nodule
  • Pain upon pressure
Term
What is hemangioma?
Definition
Proliferation of blood vessels
Term
Hemangioma is common in head and neck region in what percentage of cases?
Definition
60 percent
Term
Hemangioma is more common in which sex?
Definition
Females
Term
What size is hemangioma?
Definition
May be several centimeters
Term
Hemangioma commonly occurs where in oral cavity?
Definition
  • Lips
  • Tongue
  • Buccal mucosa
  • Palate
Term
What is port wine stain?
Definition
Unilateral hemangioma on the face due to division of trigeminal nerve
Term
What are two types of hemangioma?
Definition
  • Capillary
  • Cavernous
Term
What percentage of hemangioma regress by age nine?
Definition
50 to 90 percent
Term
How do you treat hemangioma?
Definition
  • Radiation
  • Cryosurgery
  • Sclerosing agents
  • Steroids
  • Interferon
  • Lasers
Term
How do you differentiate hemangioma?
Definition
  • Diascope
  • Excisional not incisional biopsy
Term
What are other clinical features of hemangioma?
Definition
  • Asymptomatic
  • Often congenital
  • Flat or raised deep blue lesion
  • Not varices
Term
What are birthmarks?
Definition
Hemangioma or large flat lesions of the skin
Term
Hemangioma also occurs in bone. What does it look like?
Definition
Honey combed appearance
Term
What is another name for hereditary hemorrhagic telangiectasia?
Definition
Rendu-osler-weber disease
Term
Hereditary hemorrhagic telangiectasia commonly occurs where?
Definition
  • Lips
  • Tongue
  • Buccal mucosa
  • Gastrointestinal tract
  • Finger tips
Term
What is an early sign of hereditary hemorrhagic telangiectasia?
Definition
Epistaxis
Term
What are other clinical features of hereditary hemorrhagic telangiectasia?
Definition
  • Uncommon
  • Repeated hemorrhage if on surface
  • Increases with age
  • Form of hemangioma but hard to blanch
Term
Hereditary hemorrhagic telangiectasia may cause what?
Definition
  • Anemia due to gastrointestinal bleeding
  • But not life threatening 
Term
What is sturge weber syndrome?
Definition
Variant of hemangioma of the trigeminal nerve
Term
What is present at birth in skin supplied by the trigeminal nerve?
Definition
"Portwine nevi"
Term
Neurological manifestations of sturge weber syndrome are related to what?
Definition
Angiomas and calcifications
Term
What are neurological manifestations of sturge weber syndrome?
Definition
  • Convulsive disorders
  • Mental retardation
Term
What are other clinical features of sturge weber syndrome?
Definition
  • Rare
  • Usually unilateral
  • May have vascular hyperplasia of the oral cavity
Term
Lymphangioma most commonly occurs where?
Definition
  • Tongue
  • May cause macroglossia
Term
What is cystic hygroma?
Definition
  • Rare variety of lymphangioma
  • Large cyst like lymphatic vessels
  • Of the neck
Term
What are other clinical features of lymphangioma?
Definition
  • Most present at birth
  • Colorless sometimes slightly red
  • May be papillary
Term
What causes lymphangioma?
Definition
  • Benign tumor
  • Or hamartoma of lymphatic vessels
Term
How do you treat lymphangioma?
Definition
  • Surgery only treatment of choice
  • Tend to recur
Term
What is leiomyoma?
Definition
Uncommon benign tumor of smooth muscle
Term
Leiomyoma usually occurs where?
Definition
Posterior portion of tongue
Term
What are other clinical features of leiomyoma?
Definition
  • Slow growing encapsulated mass
  • Painless
  • Firm
  • May be multinodular
Term
What is rhabdomyoma?
Definition
Rare benign tumor of striated muscle
Term
Rhabdomyoma most commonly occurs where?
Definition
Tongue
Term
What is the malignant counterpart to rhabdomyoma?
Definition
Rhabdomyosarcoma
Supporting users have an ad free experience!