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Oral Pathology
Common Lesions in the Oral Cavity
58
Pathology
Undergraduate 2
11/29/2011

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Term
Cyst
Definition
abnormal sac cavity lined with epithelium and enclosed in a connective tissue capsule
-radiolucent, well defined, unilocular or multilocular
-peripheral(tissue)
-centra (bone)
Term
Dentigerous Cyst
Definition
-follicular cyst
-around crown of unerupted tooth or developing tooth
-enucleated
-most common
Term
Eruption Cyst
Definition
-in soft tissue around erupting tooth
Term
Primordial Cyst
Definition
-cyst develops instead of tooth
-tooth will be missing
-uni or multi locular radiolucency
Term
Odontogenic Keratocyst
Definition
-has characteristic histology
-high rate of recurrence
-well defined, multilocular radiolucency
-moves teeth, resorbs roots
-needs aggressive surgical removal
Term
Lateral Periodontal Cyst
Definition
-between roots of adjacent teeth
-mand-canine premolar area
-radiolucent
Term
Ankylosis
Definition
-fused to surrounding bone
-usually primary teeth
-prevents eruption of permanent teeth
Term
Trisomy 21
Definition
-may have fissured tongue, premature loss of teeth
-periondititis
-hypodontia, and crowding
Term
Cyclic Neutropenia
Definition
-cyclic decrease in # of neutrophils
-severe ulcerative gingivitis
-needs pre med
Term
Cleidocranial dysplasia
Definition
-mushroom shaped head
-underdeveloped maxilla
-numerous supernumerary teeth
-multiple cyst with impacted teeth
-clefting
Term
Gardener's Syndrome
Definition
-familial colorectal polyps
-osteomas in maxilla
-multiple odontomas, hypercementosis
Term
Basal Cell Nevus Syndrome
Definition
-multiple nevi with basal cell carcinomas on skin
-multiple odontogenics keratocysts
-ameloblastomas in jaws
Term
Osteogeneis imperfecta
Definition
-abnormally formed bones that fracture easily
Term
Hereditary Hemorrhagic Telangectasia
Definition
-multiple capillary dilations of skin and mucous membranes
-skin of face has spider veins
-common on anterior tongue
Term
White Sponge Nevus
Definition
-buccal mucosa is white and corrugated
-bilateral
-thick layer of keratin that desquamates leaving raw surface
Term
Amelogenesis Imperfecta
Definition
-hypoplastic(thin enamel)
-hypocalcification(soft enamel)
-hypomaturation (enamel easily chipped away)
Term
Dysplasia
Definition
-disordered growth
-irreversible
-premalignant lesion
-environmental or internal stimulus
Term
Neoplasia
Definition
-new uncontrolled cell growth
-environmental or internal stimulus
-irreversible
-squamous cell carcinoma
Term
Benign Neoplasms
Definition
-grow more rapidly than normal tissue
-do not invade
-resemble and function like normal tissue
-damage due to physical bulk
Term
Malignant Neoplasms
Definition
-grow rapidly and invasively
-may not function or resemble normal tissue
-necrosis, destruction, and ulceration of tissues
-metastasize
Term
Lymphatic method of Metastasis
Definition
-carcinomas
-in lymph nodes that drain the area
Term
Hematalogical method of Metastasis
Definition
-sarcomas
-in line of venous drainage
-to distant organs
Term
Surgical Manipulation (Metastasis)
Definition
-surgery may produce metastatic neoplasms in adjacent tissues along surgical site
Term
Leukoplakia
Definition
-white patch or plaque
-hyperkeratosis
-hyperkeratosis with dysplasia
-carcinoma
Term
Erythroplakia
Definition
-red patch or plaque
-epithelium has no keratin
-usually has dysplasia
Term
Squamous Cell Carcinoma
Definition
-90% of all oral cancers
-chronic ulcer or red patch (asymptomatic)
-poorly defined radiolucent areas
Term
Verrucous Carcinoma
Definition
-slow growing papule or nodule
-white and red surface
-good prognosis
Term
Basal Cell Carcinoma
Definition
-skin but not in mouth
-non healing ulcer with rolled borders
-must treat early (with liquid nitrogen)
Term
Salivary Gland Neoplasm : Adenomas
Definition
-minor salivary glands
-hard palate
-enlarge slowly
- don't ulcerate
-benign
*pleomorphic adenoma
*monomorphic adenoma
Term
Salivary Gland Neoplasm: Adenocarcinomas
Definition
-usually parotid gland
-enlarge rapidly
-ulcerate
*adenoid cystic carcinoma
*mucoepidermoid carcinoma
Term
Ameloblastoma
Definition
-mand molar area and ramus
-can be associated with dentigerious cyst
-slow growing, destructive
-asymptomatic
-multilocular radiolucency
-benign
Term
Benign Cementoblastoma
Definition
-produces cememtum
-fused to roots
-well defined radiopaque mass
-surround by radiolucent halo
Term
Odontoma
Definition
-composed of tooth tissues
-do not erupt
-can be compound or complex
Term
Compound Odontoma
Definition
-cluster of small teeth with radiolucent halo
-ant maxilla
Term
Complex Odontoma
Definition
-radioopaque mass surround with radiolucent halo
-post. part of mouth
Term
Peripheral Odontogenc Neoplasms
Definition
-peripheral ossifying fibroma
-sessile or pedunculated nodule from IP
Term
Cementoma
Definition
-not a neoplasm
-common
-mand ants
-asymptomatic
-radiolucent, gradually becomes radiopaque
-will be with a non vital tooth
Term
Lipoma
Definition
-benign neoplasm of fat cells
-usually on buccal mucosa
-yellowish papule or nodule covered with thin epithelium
Term
Neurofibroma and Neurilemmoma (schwanoma)
Definition
-benign nerve neoplasm
-usually on tongue
-malignancies are very rare
Term
Congenital Epulis of the newborn
Definition
-benign
-present at birth (usually girls)
-max ant gingival
-does not recur
Term
Hemangioma
Definition
-benign neoplasm of blood vessels
-red or blue nodule blanches with pressure
-present at birth
-may undergo remission spontaneously
Term
Lymphangioma
Definition
-benign neoplams of lymphatic tissue
-present at birth
-usually on tongue
Term
Karposi's Sarcoma
Definition
-malignant neoplasm of blood vessels
-AIDS patients and immunosuppressed
-on gingiva and hard palate
Term
Nevus
Definition
-benign neoplasm of melanocytes
-refer if ulcerated, growing, spreading or changing color, bleeding or asymmetrical
Term
Malignant Melanoma
Definition
-malignant neoplams of melanocytes
-prolonged sun exposure
-if in oral cavity, usually a metastatic lesion
-on palate and max gingiva
Term
Osteoma
Definition
-benign neoplasm of bone
-slow growing, asymptomatic
-well defined radiopaque mass
-Gardener's Syndrome
Term
Osteosarcoma
Definition
-malignant neoplasm of bone
-diffuse painful enlargement of bone
-mobile teeth, toothaches, parathesia
-poorly defined radiolucency or radiopacity which destroys adjacent structures
Term
Leukemia
Definition
-malignant neoplasm of white blood cells
-acute or chronic
-gingival enlargement
Term
Lymphoma
Definition
-malignant neoplasm of lymphoid tissue
-hodgkins, non0hodgkins
-gradual enlargement of lymphnodes
Term
Multiple Myeloma
Definition
-malignant neoplasm of plasma cells
-destructive lesions in bones
-bone pain, enlargment, pathological fractures
Term
Metastatic neoplasms to the Jaws
Definition
-metastasize from distant lesions
-uncommon
-to jaws: breast, lung, prostate, kidney, thyroid
-poorly defined radiolucency
Term
Fibrous Dysplasia
Definition
-bone replaced by abnormal fibrous connective tissue
-light brown macules on skin (cafe au lait)
-diffuse, dense, uni or multi locular radopacity
Term
Pagent's Disease
Definition
-metabolic bone disease
-painful bony enlargement
-patchy radiolucency and radiopacity
Term
Hyperthyroidism
Definition
-excessive production of thyroid hormone
-premature exfoliation of primary teeth
-in children
Term
Hypothyroidism
Definition
-decreased output of thyroid hormones
-thickened lips, enlarged tongue, delayed eruption
-in children
Term
Addison;s Disease
Definition
-primary adrenal cortical insufficiency
-brown pigmentation of skin and melanoticmacules on oral mucosa
Term
Agranulocytosis
Definition
-results in leukopenia and neutropenia
-caused by immune, drugs, chemicals
-necrotizing ulcers, bleeding, aggressive perio
-all dental treatment contraindicated
Term
Purpura
Definition
-cause by thrombocytopenia
-bruises, petechia, bleeding
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