Term
Succinylcholine(Anectine)
(20mg/ml)
MOA: Ach Agonist
Neuromuscular Blocker |
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Definition
Adult IV Intub: 0.6 (0.3-1.1 mg/kg)
Maintenance: 30-150 mcg/kg/min
RSI: 1-1.5mg/kg
Onset for Intubation: 30-60sec
Peak: 60 sec
Duration: 4-6 min
Half-life: 2-4 min
Elimination: Plasma Cholinesterases
** Can use to break a laryngospasm-20mg bolus
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Term
Rocuronium(Zemuron)
(10mg/ml)
Class: Aminosteroids
MOA: Nicotinic M Antagonist
Neuromuscular Blocker |
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Definition
Adult IV Intub: 0.6mg/kg (0.45-1.2)
Maint: 6-16mcg/kg/min
RSI: 0.6-1.2mg/kg
Onset for Intub: 60-90 sec
Peak: 1-3 min
Duration: 30-75 min
Half-life: 60-70 min
Elimination: Renal/ Hep |
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Term
Vecuronium(Norcuron)
(1mg/ml)
Class: Aminosteroids
MOA: Nicotinic M Antagonist
Neuromuscular Blocker |
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Definition
Adult Intub: 0.1mg/kg(0.08-0.2mg/kg)
Maint: 0.8-1.2mcg/kg/min
RSI: 0.3-0.4mg/kg
Onset for Intub: 2-3min
Peak: 3-5min
Duration: 30min
Half-life: 1.5hrs
Elimination: Renal/Hep
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Term
Pancuronium(Pavulon)
(1mg/ml)
Class: Aminosteroids
MOA: Nicotinic M Antagonist
Neuromuscular Blocker |
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Definition
Adult IV Intub: 0.06-0.12mg/kg
Maint: 1-15mcg/kg/min
Onset for Intub: 2-3 min
Peak: 3-5 min
Duration: 60-120min
Half-life: 2hrs
Elimination: Renal/Hep
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Term
Cisatracurium(Nimbex)
(2mg/ml)
Class: Benzylisoquinolines
MOA: Nicotinic M Antagonist
Neuromuscular Blocker |
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Definition
Adult IV Intub: 0.15(0.15-0.2)mg/kg
Maint: 1-3mcg/kg/min
RSI: 0.4mg/kg
Onset: 2-3min
Peak: 3-5min
Duration: 30min
Elimination: Hoffman
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Term
Atracurium(Tracrium)
(2mg/ml)
Class: Benzylisoquinolines
MOA: Nicotinic M Antagonist
Neuromuscular blocker
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Definition
Adult IV Intub: 0.6(0.3-0.6)mg/kg
Maint: 3-15mcg/kg/min
Onset for Intub: 2-3min
Peak: 3-5min
Duration: 30min
Half-life: 30min
Elimination: Hoffman
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Term
Mivacurium
(2mg/ml)
Class: Benzylisoquinolines
MOA: Nicotinic M Antagonist
Neuromuscular Blocker |
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Definition
Adult IV Intub: 0.2(0.15-0.25)mg/kg
Maint: 5-15mcg/kg/min
Onset for Intubation: <90sec
Peak: 1-3min
Duration: 12-20min
Half-life: 2-4min
Elimination: Plasma Cholinesterase |
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Term
2-Chloroprocaine(Nesacaine)
Class: Ester
MOA: Ester Na+ Channel Blocker
Local Anesthetic
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Definition
Relative potency: 1(on a scale of 1-8)
pKa: 9.1
Onset: Rapid
Duration:
*prolonged with Epinephrine 1:200000 (200-300mcg intrathecal) or Phenylephrine(2-5mg intrathecal)
Spinal: 0.5-1hr
Epidural: 1-1.5hr
Toxic doses:
**Not to exceed 1000mg
Plain- 11mg/kg
With epi- 14mg/kg
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Term
Tetracaine(Pontocaine)
Class: Ester
MOA: Ester Na+ Channel Blocker
Local Anesthetic |
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Definition
Relative potency: 8(scale 1-8)
pKa: 8.6
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