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Opt 733 Glaucoma Exam 1
Dr Lingel Lecture 4
33
Medical
Graduate
09/19/2012

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Cards

Term
What single test has the highest specificity and best precision for diagnosing glaucoma?
Definition
ONH evaluation
Term
Can NFL loss occur before evidence of VF loss?
Definition
yes, which is why ONH is important
Term
What are the 4 main ways to measure ONH disc size?
Definition
Planimetry

scanning laser tomography

Contact lens (central 3 mirror gonio)

High plus
Term
What are the correction factors for contact lenses and high plus lenses?
Definition
1.27 for contact

HP lens depends on power/brand
Term
What is the equation for calculating ONH area?
Definition
H X W x pi/4
Term
What is ONH 'notching'?
Definition
a localized irregularity in the radius of the optic cup,red flag for glaucoma
Term
Where is ONH thinning most common to occur first?
Definition
superior and inferior
Term
How does the central retinal artery (CRA) induce notching?
Definition
The CRA trunk is more commonly nasal-superior and notching tends to occur opposite in the inferior-temporal area
Term
Why does nerve fiber loss due to glaucoma require a evaluation rim to disk and not just cup to disc ratios?
Definition
If an ONH is elliptical, then changes in C/D vertically vs horizontally will be different and more difficult to determine expressed as a percentage of the cup, while if it is expressed as a percentage of rim tissue, any changes will be more apparent
Term
When determining rim to disk and cup to disk ratios, what is the primary mathematical principle to keep in mind?
Definition
Both the vertical and horizontal proportions should add up to '1.0'
Term
When does the C/D horizontal vs vertical proportion indicate glaucoma concern?
Definition
Horizontal C/D divided by Vertical C/D should be greater >1 with a typical value of 1.15-1.19
Term
Is diffuse arteriole narrowing pathognomonic for glaucoma?
Definition
No, though it can occur in glaucoma, it can occur in many other types of ONH damage
Term
What is indicated by shifting locations of vessels over time?
Definition
Usually a sign of more severe damage in glaucoma. A senstive way to discern ONH damage secondary to glaucoma.
Term
What is 'bayoneting' of ONH blood vessels?
Definition
It comes to a very fine point due to the BV dropping off into the cup. However, it is not a reliable indicator of glaucoma.
Term
What is a splinter hemorrhage?
Definition
Another name for Drance hemorrhage, common (but not limited to) glaucoma damage.
Term
What are common causes of splinter hemorrhages?
Definition
Glaucoma

PVD

Resolving BRVO

Diabetic Retinopathy
Term
Regardless of cause, what does an optic disc hemorrhage indicate?
Definition
Tx is necessary, so determine the active pathology
Term
How long does an optic disc hemorrhage take to resolve?
Definition
10 weeks
Term
In an advanced glaucoma patient, what do optic disk hemorrhages signify?
Definition
unfavorable prognosis
Term
What is peripapillary pigmentary atrophy?
Definition
mottled appearance to RPE seen around the disc
Term
What is beta atrophy?
Definition
central zone of RPE and choriocapillaris atrophy leading to visibility of choroidal vessels and sclera
Term
What is alpha atrophy?
Definition
peripheral zone RPE atrophy surrounding the ONH
Term
How does alpha atrophy compare to a choroidal crescent?
Definition
alpha atrophy is more mottled and less uniform, irregular borders
Term
What is the suspected etiology of peripapillary pigment changes?
Definition
optic nerve ischemia
Term
Where is peripapillary pigmentary atrophy typically found?
Definition
temporal
Term
Is alpha atrophy present in normal eyes?
Definition
yes, it is commonly seen
Term
Is beta atrophy present in normal eyes?
Definition
not commonly. Usually pathologic.
Term
What is the progression of peripapillary pigmentary atrophy?
Definition
Patches typically start as alpha and progresses to beta over time if pathologic mechanism is not intervened
Term
What does peripapillary pigment atrophy usually indicate is happening in the eye?
Definition
advanced damage, often associated with rim loss in the same sector
Term
What is an acquired pit of the ONH?
Definition
sharp localized depression of lamina cribrosa
Term
What color is typically seen around acquired pts of the ONH?
Definition
Usually found in pallorous ares of ONH
Term
What is the most likely location of acquired pits of the ONH?
Definition
inferior temporal quadrant (opposite of CRA trunk?)
Term
What pathology are acquired pits of the ONH most commonly found in?
Definition
normotensive glaucoma
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