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Opt 631 Exam 1 Endtothelial Dystrophies
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20
Medical
Graduate
09/25/2011

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Cards

Term
What is Fuch's Endothelial Dystrophy?
Definition
Guttata like dots under the endothelial layer of the cornea, in descemet's.
Term
What is CCT for Fuch's Endothelial Dystrophy?
Definition
>600 microns, very thick
Term
What is the mechanism of Fuch's Dystrophy?
Definition
As the endothelial cells are stretched over the guttata the endothelial pumps are disrupted causing stromal edema and ultimately epithelium
Term
What are the SE's of Fuch's Dystrophy?
Definition
VA's drop

glare/photophobia

Edema

RCE
Term
What is the tx for Fuch's Dystrophy?
Definition
hypertonic sol'n

hot air (hair dryer)

SCL

Dilation to open pupil around central clouding
Term
What kind of dilating drops induces cycloplegia?
Definition
parasympatholytic. Sympathomimetic only dilate pupil
Term
What is Congenital Hereditary Endothelial Dystrophy?
Definition
Similar to Fuch's, but has 2 forms: Recessive w/ nystagmus and Dominant w/o nystagmus.

Diffuse ground glass edema in stroma and epithelium
Term
What is Posterior Polymorphous Dystrophy?
Definition
Endothelial layer undergoes polymorphous change leading to multiple cell thickness of endothelium
Term
What are the SE's of Posterior Polymorhous Dystrophy?
Definition
generally none. May have photophobia or decreased VA's
Term
What is the tx for Posterior Polymorphous Dystrophy?
Definition
lubrication

hypertonic sol'n

bandage SCL

rarely surgical

RCE
Term
What is corneal Pannus?
Definition
asymptomatic neovascularization of fibrous tissue bed. Result of chronic inflammatory response
Term
What is the tx for corneal pannus?
Definition
reduce/discontinue CL wear

treat underlying cause
monitor size/extent

vasoconstrictors
Term
What is a pterygium?
Definition
wing shaped fibrovascular tissue fold over cornea from limbus
Term
What are the SE of pterygium?
Definition
May induce astigmatism/corneal distortion
Term
What are DDX of pterygium?
Definition
limbal dermoid

pannus

neoplasm

papilloma or melanoma
Term
What is the tx for pterygium?
Definition
Protect eye from UV

lubrication

NSAID

Vasoconstrictors

mild steriod to reduce inflammation (fluoromethalone)
Term
What is Interstitial Keratitis?
Definition
Hazing of cornea
Term
What is the cause of Interstitial Keratitis?
Definition
90% syphillis. May be Lyme dz, TB or Herpes simplex. Some are congental.
Term
What are the triad of finings in interstitial keratitis?
Definition
stromal infiltration

stromal thinning

neovascularization
Term
What are the s/sx of Leutic or congenital syphillis?
Definition
saddle nose bridge, notched incisor teeth
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