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Opoid Agonists
Pain and Drugs affecting the CNS
7
Pharmacology
Undergraduate 2
05/26/2016

Additional Pharmacology Flashcards

 


 

Cards

Term

Morphine Sulfate (Roxanol, MS Contin)

Codeine Sulfate

Fentanyl (Duragesic Actiq)

Methadone, Oxycodone,

Hydromorphone Hydrochloride (Dilaudid)

Hydrocodone(Vicodin)

 

All Schedule C-2 Controlled Substances

 

Definition

INDICATIONS

analgesia-Moderate to severe/manage pain

reduces myocardial oxygen requirements

ADVERSE EFFECTS

constipation, urinary retention, respiratory depression, itching

NSG MGMT

monitor resp rate, n/v, uringary retention, itching due to histamine release(not and allergic reaction) mental alertness, addiction, opoid tolerance, dispose of by folding patches in half

Term

OPOID ANTAGONISTS

 

Naloxone hydrochloride (Narcan)

Definition

 

 

Use for Respiratory Distress

 

Term

NONopioid and Misc. Analgesics

 

Acetaminophen (Tylenol) is the most widely used nonopoid analgesic

 

 

 

Definition

INDICATION

ANTIPYRETIC (brings temp down)

NO ANTIINFLAMMATORY effect

ADVERSE EFFECTS

(Hepatic) Liver toxicity

NSG MGMT

4gm maximum in 24h for adults

No more than 2gm in those with liver failure or advanced age

Term

Tramadol (Ultram)

 

Weak bond w/opoid receptor

Definition

INDICATIONS

Moderate to moderately severe pain

 

NSG MGMT

assess pain relief

increase risk of developing serotonin syndrome when taken with SSRI

Term

TRANSDERMAL LIDOCAINE

on 12h off 12h

Definition

INDICATION

topical anesthethic for pain, postherpetic neuralgia(shingles), back pain

ADVERSE EFFECTS

arrhythmia

NSG MGMT

up to 2 patches can be placed at once, systemiv drug toxicity

 

Term

Nonsteroidal anti-inflammatory drugs (NSAID)

(When taken once daily keeps platlets from clumping)

 

Asprin (ASA)

Ibuprofen (Motrin, Advil)-Naproxen 2nd most common

Ceecoxib (Celebrex)-a COX-2 inhibitor

Definition

Action

leukotriene patheway, the prostaglandin pathway

INDICATION

GI intolerance, bleeding, renal impairment, Acute kidney injury(AKI),/Renal toxicity, Hepatic toxicity, toxic effect of ASA ototoxicity(tinnitus and hearing loss) Nonsalicylate NSAIDs overdose Hemodialysis of no value in eliminating drug, All NSAIDS FDA:BLACK BOX warning cardiovascular risk

NSG MGMT

ASA enteric coated dissolves in small intestine, Asprin triad- assess asthma, nasal polyps, and rhinitis

Term

DRUGS FOR GOUT

Indocin, Motrin(first line treatment)

 

Allopurinol (Zyloprim)

 

Colchicine

 

Probenecid

Definition

Action: Allopurinol

to prevent uring acid production

 

Action: Colchicine

reducing the inflammatory response

 

Action: Probenecid

inhibit reabsorption of uric acid in the kidney

 

Take with food of mild, plenty fliuds

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