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Opioids
na
9
Pharmacology
Professional
05/02/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Morphine
Definition
-alters the perception of pain
-relief of dyspnea accompanying pulmonary edema
-decreased sensitivity of the respiratory center to CO2
-miosis that can be blocked by atropine
-vasodilation of cerebral blood vessels
Term
Butorphanol
Definition
-morphinian type synthetic opiod analgesic
-partial agonist and antagonist activity at the mu receptor and agonist activity at the k opiod receptor
Term
Pentazocine
Definition
-when combined with naloxone, best prescriped for a patient suffering from chronic back pain and a history of drug abuse
-k-agonist, not liked by addicts
Term
Fentanyl
Definition
-mu opioid agonist
-adverse effects can include respiratory depression, constipation, nausea
-produces analgesia, sedation, mood alteration
-chronic use could produce physical dependence/addiction
-synthetic compound 100x more potent than morphine
Term
Methadone
Definition
-used in the heroin withdrawal program
-has a long half life and can precipitate the withdrawal from heroin
-In order to help heroin addicts “kick” their drub habit, this drug is routinely administered in a long-term, closely supervised program
Term
Nalbuphine
Definition
-synthetic opioid
Term
Dezocine
Definition
-opioid analgesic
-produces dysphoria and hallucinations at high doses
-acts on k receptor
Term
tramodol (Ultram)
Definition
-weak agonist actions at the mu opiod receptor
-releases serotonin
-inhibits the reuptake of norepinephrine
Term
Naloxone
Definition
-combine with pentazocine for the best prescription for a patient suffering from chronic back pain and a history of drug abuse
-use in heroin OD, hypovolemia shock, spinal injury and eating disorders
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