Term
| What are the pathophysiological manifestations of Osteoarthritis |
|
Definition
Loss of Cartilage
Eburnation
Subcondral Cysts
Osteophytes
Heberden's Nodes-Soft Tissue DIP Masses |
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Term
| What are comon organisms to consider in Suppurative Arthritis who are Sexually active, children, or Sickle cell |
|
Definition
Sex: Gonorrhea
Children: H. Flu
Sickle: Salmonella |
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Term
| What are the manifestations of Rheumatoid arthritis and what are some syndromes associated with RA? |
|
Definition
Fever, Malaise
RA Nodule
Distal joints->Proximal Joints
Syndromes: Felty's Syndrome, Ankylosing Spondylitis, Juvenille RA |
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Term
| What is the most common cause of mortality in Rheumatoid Arthritis |
|
Definition
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Term
| What is the pathophysiology of Rheumatoid Arthritis |
|
Definition
Cytokine release causes synovial proliferation
Pannuses form and invade the Joint cartilage and bone
Eventually Ankylosis |
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Term
| What is the typical progression of Lyme's Disease and how is it diagnosed |
|
Definition
Skin lesion-> CV/CNS-> Arthritis
Dx: 2 Step Serology-Elisa, then Anti-borrelia protein immunoassay |
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Term
| What is the pathogenesis of gout? |
|
Definition
Overproduction or Underecretion of Uric Acid causes Hyperurecemia
Crystal pricipatation in joints-> Inflamation |
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|
Term
| How does gout typically progress |
|
Definition
| Asymptomatic-> Recurrent-> Chronic-> Ankylosis |
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|
Term
| What is Nodular Tenosynovitis and who is likely to present with it? |
|
Definition
| Typically a mass on the tendon found in women |
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Term
| What is the epidemiology, etiology and manifestations in each of the seronegative spondyloarthropathies |
|
Definition
Ankylosing Spondylitis: Young Males, Sacroiliac Joints
Reactive Arthritis: Triad-arthritis, urethritis, conjunctivitis
Enteropathic Artritis: Post-GI infections-Yersina, Camplylobacter, Salmonella, Shigella
Psoriatic Arthritis: DIP joints, pitting fingernails, and large joints |
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Term
| What is the most common mass to develop in the joints of the hand? |
|
Definition
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