Term
| What are the Superficial Mycoses organisms and the diseases they cause? |
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Definition
Malassezia: Tinea Vesicolor
Seborrheic Dermatitis
Dandruff
Exophiala: Tinea Nigra
Piedraia: Black Piedra:Hard black nodules on hair
Trichosporon: White Piedra-Similar to Nits |
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Term
How does KOH appear for each of the following disease swabs: Tinea vesicolor, Tinea Corrporis, Mucosal Albicans
Mucosal Glabrata |
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Definition
Tinea Vesicolor: Hyphae and Yeast
Tinea Corporis: Hyphae and Conidia
Mucosal Albicans: Hyphae and Yeast
Mucosal Glabrata: Yeast, w/o hyphae |
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Term
| How do you distinguish the genera of Dermatophytes? |
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Definition
(Macroconidia;Microconidia)
Epidermophyton:Thin wall,2-4; none
Trichophyton:Thin Wall, many; Many
Microsporum:Thick wall, many; Few
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Term
| What reservior of dermatophytes causes the most inflamatory disease? |
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Definition
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Term
| What are the diseases of dermatophytes |
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Definition
| Tinea capitis, pedis, cruris, corporis, unguium, barbae |
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Term
| What are the virulence factors of the dermatophytes and Candidia albicans |
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Definition
Dermatophytes: Keratinases
Candidia albicans: Extracellular Lytic Enzymes, Adhesins: Agglutin, Integrin, Hyphal Wall,
Yeast Hyphae Dimorphism |
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Term
| What is the main organism that causes sucutaneous mycoses and what are the manifestations |
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Definition
Sporotrichosis-Sporothix schenkii
Diseases: Primary Sporotrichosis
Lymphocutaneous sporotrichosis
Disseminated Sporotricosis |
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Term
| What are the major organisms that cause Mucosal Mycoses and what are the manifestations |
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Definition
Candida albicans, glabrata, parapsilosis, tropicalis, krusei
Diseases: Vulvovaginitis
Oral-pharyngeal Candiadiasis: Thrush
Esophogeal or GI Candidiasis
Cutaneous Candidiasis: Diaper Rash
Disseminated Candidiasis: Immunosurpressed
Chronic Candidiasis: T-cell deficient |
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Term
| What candida are typically resistant to azoles |
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Definition
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Term
| What candida have a higher incidence in the elderly and which in children <1 yr old |
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Definition
Glabrata: Elderly
<1 yr old: Parapsilosis |
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Term
| What drugs are used to treat Onychomycosis, Disseminated Mucosal, Immunocompromised, Simple Mucosal, simple dermatophyte, severe dermatophyte |
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Definition
Onychomycosis: Nail Laquers
Immunocompromised: Fluconazole Prophilactic
Simple Mucosal: Nystatin
Disseminated Mucosal: IV Ampho B or Echinocandin
Simple Dermatophyte: Topical or Keratolytic
Severe Dermatophyte: Oral terbinafine or Intraconazole
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