Term
| What are the characteristics that make an agent good for bioterrorism? |
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Definition
Infectivity
Virulence
Lethality
Incubation Period
Contasgious
Stable |
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Term
| What is the definition of bioterrorism |
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Definition
Use of biologically derived agents to harm others
Intent is to intimidate or increase fear |
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Term
| What are the Virulence factors of Anthrax? |
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Definition
Spores
Capsule: Antiphagocytic with D-Glutamic Acid
Toxins: Edema-calmodulin dep. adenylate cyclase
Lethal-Zinc metalloprotease cleaves MAPKK-> apotosis
Anthrolysin O-Pore former, TLR4 Agonist |
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Term
| What is the presentation of Cutaneous Anthrax |
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Definition
Erythematous Papule
Fluid filled Vesicle
Ulceration-> Black Scab, Eschar |
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Term
| What is the presentation of Inhalation anthrax |
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Definition
Prominent Superior Mediastinal Nodes
Systemic infiltration(Lung, Vessel, CSF) |
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Term
| How is Bacillus Anthracis Diagnosed and Treated |
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Definition
Gram Stain and Culture on Blood Agar
Serology and Immunoassay exist
Rx: Many Anti-biotics |
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Term
| Is there a vaccine to Anthrax |
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Definition
| Yes, but only used in lab and Military |
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