Term
| How does Rickettsia compare to Gram negative organisms |
|
Definition
Same: Lipopolysacciride and Diaminopimelic Acid
Different: Obligate Intracellular, Don't gram stain |
|
|
Term
| What is the virulence of Rickettsia |
|
Definition
Replication in Endothelial cells
Phagosome Escape |
|
|
Term
| What is the virulence of Yersina Pestis |
|
Definition
V-W antigen and F-1 Antigen-> Resist Phago
Type III Secretion system of YOPS |
|
|
Term
| What is used to treat Rickettsia? |
|
Definition
Doxycylcine
Tetracycline
Chloramphenicol
Eyrthromycin
Sulfonimide-Make it Worse
Penicillin Uneffective |
|
|
Term
| How do you treat the plague |
|
Definition
|
|
Term
| What is the presentation of RMSF |
|
Definition
Tick
Systemic Signs
Rash Soles and Palms
DIC
|
|
|
Term
| How does rickettsial Pox present |
|
Definition
Vesicular Rash and local Eschar
Regional Lymphadenopathy
Systemic Signs |
|
|
Term
| What is the presentation of rickettsia typhus |
|
Definition
Systemic
Trunk Rash
Complications: CNS, Myocarditis
Long-term: Brill-Zinsser Disease |
|
|
Term
| What is the pathogenesis of Ehrlichia |
|
Definition
Tick
Systemic signs
Leukopenia Thromocytopenia |
|
|
Term
| What is the species and vector of each of the rickettsial dieseases |
|
Definition
RMSP: Rickettsii, TIck
Pox: akari, Mouse mite
Typhus: prowazekii, Tick |
|
|
Term
| What is the epidemiology of Rickettsial Pox |
|
Definition
|
|
Term
| What are the charcteristics of Yersina pestis |
|
Definition
Gram(-) Rod
Bipolar Staining
Facultative Intracellular |
|
|
Term
| What is the pathogenesis of the plague? |
|
Definition
Flea/Rodent bite
Bubo Formation
DIC
or
Pneumonia
w/o treatment=Death |
|
|
Term
| What states is the plague more prevailent in? |
|
Definition
|
|
Term
| What is the pathogenesis of tularemia? |
|
Definition
Four diffent Ways
Ulceroglandular: Ulcerating papule
Glandular: Vector spread
Oculoglandular
Typhoidal: bacteremia seeds organs |
|
|
Term
| How do you treat tularemia |
|
Definition
|
|
Term
| How does Pastuerella Multocida Present |
|
Definition
Dog/Cat Scratch/Bite (In animal GI/Respiratory)
Diffuse Cellulitis w/ Erythema Boarder
|
|
|
Term
| What is the pathogenesis of Brucella? |
|
Definition
Ingestion: Feces, Urine, Milk animal exposure
Granulomatous Nodules and Abcesses in reticuloendothelial organs
Chronic: Wt Loss and Night Sweats |
|
|
Term
| What are the characteristics of the brucella organism? |
|
Definition
Gram - Rod
Catalase
Oxidase
Trypticase Soy + CO2 culture
Facultative Intracellular |
|
|
Term
| What is the Agent, Reservoir and Mode of Transmission of Plague? |
|
Definition
Agent: Yersina Pestis
Reservoir: Fleas/Rodents (Four Corners states)
Transmission: Flea/Rodent Bite, or Respiratory
|
|
|
Term
| What is the Agent, Reservoir and Mode of Transmission of Ehrlichoiosis? |
|
Definition
Agent: Ehrlichia Genera
Reservoir: Cattle, Domestic Animals
Transmission: Deer and Dog Tick |
|
|
Term
| What is the Agent, Reservoir and Mode of Transmission of Brucellosis? |
|
Definition
Agent: Brucella
Reservoir: Animals
Transmission: Ingestion of contaminated milk or animal meat |
|
|
Term
| What is the Agent, Reservoir and Mode of Transmission of Tularemia? |
|
Definition
Agent: Francisella tularensis
Reservoir:Rabbits, Squirels, Musrats, Beavers, Deer
Transmission: Rabbit, Tick or Deerfly, Skinners |
|
|
Term
| What is a recurrance of typhus rickettsiae disease that is usually much milder |
|
Definition
|
|
Term
| What is the virulance of the orgnaism causing Rabbit Fever, Deerfly Fever, and Rabbit Skinner's Disease? |
|
Definition
| Encapsulated, facultative intracellular |
|
|
Term
| What is the virulence of the organism causing Undulent Fever, or Malta fever |
|
Definition
Catalase, Oxidase
Facultative intracellular |
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