Term
| What is the virus that causes measles and what are some key characteristics |
|
Definition
Paramyxovirus
(-) ssRNA
Fusion Factor
Hemagglutinin/Neuramidase
Matrix Protein |
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|
Term
| How are measles transmitted |
|
Definition
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Term
| What is the typical presentation of Measules |
|
Definition
Prodrome: Coryza, Conjunctivitis, Cough, Photophobia
Koplik's Spots: Red halos w/ central white spots on buccal surface
Maculopapular Rash: 5 Days, 1st day (Highest Fever) |
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|
Term
| What are the complications of Measules |
|
Definition
Bacterial Superinfection Pneumonia (Th1->Th2)
Giant Cell Pneumonia in Immunocompromised(F Protein)
Post-Infectious Meningo-Encephalitis
Subacute Sclerosing Panencephalitis |
|
|
Term
| How are measules prevented |
|
Definition
| MMR Vacine(Live Attenuated) |
|
|
Term
| How do you diagnose Measules |
|
Definition
Clinical
Koplik Spots
Rash/Prodrome
Serology |
|
|
Term
| What is the cause of Erythema Infectiosum |
|
Definition
| Paramyxovirus B-19 (+) ssDNA |
|
|
Term
| How does Fifth's disease present and what age group does it affect |
|
Definition
Phase 1: Flu-like
Phase 2: Slap-cheek Rash
Age Group: 4-15 yr old |
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|
Term
| How do you diagnose fifth's disease |
|
Definition
Clinical
Slap-cheek
Lacy Body
Serology to differentiate from Rubella |
|
|
Term
| What is the pathogenetic movement of Parvovirus B-19 |
|
Definition
URT
Viremia
Bone Marrow(Anaplastice Crisis in Sickle Cell Patients)
Secondary Viremia(Fetal Loss in 1st Trimester) |
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|
Term
| What is the cause of Roseola Exanthums |
|
Definition
HSV-6 (Large dsDNA virus)
|
|
|
Term
| What patients primarily exhibit complications of Roseola Exanthum subitum |
|
Definition
| Immunocompromised patients |
|
|
Term
| How does Roseola Exanthum subitum typically present |
|
Definition
Incubation 4-7 days
Fever 3-5 days
Rash 1-2 days
Latency |
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