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Ob-Gyn Pathology 2
Downstate > MS2 Endocrine > Ob-Gyn Pathology (Schneller): ovaries, fallopian tube, gestational
36
Medical
Graduate
03/11/2011

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Cards

Term
FIGO grade I, II, III for ovarian neoplasms
Definition
I. <5% is solid tumor
II. 5 to 50% is solid tumor
III. >50% is solid tumor
Term
most common ovarian neoplasma
Definition
serous ovarian neoplasm
Term
can present as multilocular cysts, polypoid excrescences, or papillae with psammoma bodies; assc'd with BRCA1 and BRCA2; dx?
Definition
serous ovarian neoplasm
Term
1. tumor histology similar to Fallopian tube
2. tumor histology similar to endometrium
3. tumor histology similar to uroepithelium
Definition
1. serous ovarian neoplasm
2. mucinous ovarian neoplasm
3. Brenner's tumor
Term
pseudomyxoma peritonei
Definition
mucinous ascites assc'd with mucinous ovarian tumor or appendiceal tumor
Term
can present as multilocular cysts, complex glands, or solid epithelial budding; dx?
Definition
mucinous ovarian neoplasm
Term
solid and cystic presentation, most are malignant; similar to endometrial adenocarcinoma
Definition
endometrioid tumor of ovaries
Term
nests of transitional cells on a fibrous background; most are benign; dx?
Definition
Brenner's tumor (of ovaries)
Term
inhibin+, Call-Exener bodies; dx?
Definition
granulosa cell tumor
Term
small cavities with eosinophilic fluid surrounded by granulosa cells; dx?
Definition
granulosa cell tumor; this is a Call-Exener body
Term
pt presents with hirsutism, acne, amenorrhea, and enlarged clitoris; dx?
Definition
Sertoli-Leydig cell tumor
Term
Meig's triad
Definition
ascites, right hydrothorax, ovarian thecoma-fibroma
Term
yellow and white mass on gross; spindle cells on biopsy; mostly benign; can produce excess estrogen; dx?
Definition
fibroma-thecoma
Term
most common malignant germ cell tumor; elevated serum LDH; radiosensitive; dx?
Definition
dysgerminoma
Term
child with abdominal pain or mass; AFP+; Schiller-Duval body; dx?
Definition
yolk sac tumor
Term

[image]

biopsy of ovaries in a 5yo; dx?

Definition
yolk sac tumor. this is a Schiller-Duval body (looks like a glomerulus)
Term
ovarian tumor of adult tissue showing all 3 germ layers; dx?
Definition
mature cystic teratoma
Term
2 types of monodermal teratomas
Definition
struma ovarii and carcinoid
Term
19yo with pelvic mass or pain; biopsy shows immature spinal cords; dx?
Definition
immature teratoma
Term
Krunkenberg tumor
Definition
metastasis from GI tumor to ovaries
Term

[image]

biopsy of ovary; dx?

Definition
dysgerminoma
Term

[image]

biopsy of ovary; dx?

Definition
struma ovarii (monodermal teratoma)
Term
what produces HPL? HCG?
Definition
intermediate trophoblast - HPL; syncytiotrophoblast - HCG
Term
grape-like transparent vesicles fill the uterine cavity; dx?
Definition
complete hydatidiform mole
Term
enlarged chorionic villi with cistern formation; elevated serum HCG; no fetal tissue; dx?
Definition
complete hydatidiform mole
Term
1. 46XX paternal karyotype
2. 69XXY or 92XXY karyotype
Definition
1. complete hydatidiform mole
2. partial hydatidiform mole
Term
edematous chorionic villi, enlarged; some fetal tissue; dx?
Definition
partial hydatidiform mole
Term
large hydropic villi invade myometrium and can embolize to lung or brain; dx?
Definition
invasive hydatidiform mole
Term
friable, hemorrhagic amorphous mass; no chorionic villi; dx?
Definition
choriocarcinoma
Term
choriocarcinoma can be preceded by ...(3)
Definition
complete hydatidiform mole, spontaneous abortion, or normal pregnancy
Term
1. which hydatidiform mole type is more common?
2. which has a higher risk of progressing to choriocarcinoma?
Definition
1. complete
2. complete
Term
at what age do hydatidiform moles presents?
Definition
<17yo or >75yo
Term
HCG+ intermediate trophoblast tumor
Definition
placental site trophoblastic tumor (PSTT)
Term
IUD users are at risk for...
Definition
Actinomyces infection
Term
pathogens responsible for PID
Definition
N. gonorrhea, Chlamydia, TB, Actinomyces
Term
60yo with adnexal mass, watery discharge, abdominal discomfort; dx?
Definition
Fallopian tube adenocarcinoma
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