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Nutrition & Metabolism
Study Guide 5 Biology 152
115
Biology
Undergraduate 1
05/31/2011

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Cards

Term

A measurement of the amount of energy associated with different foods is a ____________________.

 

Definition
Calorie
Term

 

Generally, cells can only use energy in the form of ____________________.

 

Definition
ATP
Term

 

The three macronutrients that the body metabolizes for energy are ____________________, ____________________, and ____________________.

Definition

 

carbohydrates, proteins, lipids

Term

 

The micronutrients that are associated with plant foods are called ____________________.

 

Definition
phytochemicals
Term

 

____________________ is considered a nutrient even though it contains no calories, macronutrients, or micronutrients.

Definition
water
Term

 

Micronutrients that serve as the organic chemical precusors of many coenzymes are ____________________.

Definition
vitamins
Term

 

Nutrients that must be consumed in the diet are called ____________________.

 

Definition
essential
Term

 

Inorganic substances involved with electrolyte balance, hemoglobin formation, and thyroid homone production are ____________________.

Definition
minerals
Term

 

____________________ is a visualization of the importance of diet and exercise in wellness and was developed by the USDA.

Definition
food pyramid
Term

 

The main caloric nutrient in the diet should be __carbohydrates________.

 

Definition
carbohydrates
Term

Most individuals should get not more than 30% of their calories from _____________

Definition
lipids
Term

 

Generally, 10% to 15% of our calories should be from ____________________.

 

Definition
proteins
Term

 

The monosaccharide of the blood that fuels most cells of the body is ____________________.

 

Definition
glucose
Term

The monosaccharide of corn and fruits is ____________________.

 

Definition
frutose
Term

 

The disaccharide of milk is ____________________.

 

Definition
lactose
Term

The disaccharide of table sugar, sugar beets, and sugar frosted flakes is ____________________.

 

Definition
sucrose
Term

 

Generally, starch is broken down into trioses and ____________________.

Definition
maltose
Term

 

____________________ is a polysaccharide from plants that can be digested by the human digestive system.

Definition
startch
Term

 

____________________ is the polysaccharide storage form of glucose in animals.

Definition
glycogen
Term

 

____________________ is a polysaccharide from plants that can NOT be digested by the human digestive system.

Definition
cellulose
Term

A soluble form of indigestible polysaccharides is ____________________.

 

Definition
pectin
Term

An insoluble form of indigestible polysaccharides is ____________________.

 

Definition
fiber
Term

____________________ amino acids are not formed quickly enough in children for protein synthesis so they must be included in the diet.

Definition
semi-essential
Term

 

Human metabolism can NOT form the ____________________ amino acids.

 

Definition
essential
Term

Human metabolism can form the ____________________ amino acids.

 

Definition
non-essential
Term

 

The proteins from plant sources are considered to be ____________________ proteins because they lack one or more of the 8 essential amino acids.

Definition
imcomplete
Term

The ____________________ rule refers to the formation of proteins only if all the amino acids required for its synthesis are available

Definition
all-or-none
Term

The term ____________________ balance refers to a protein steady state, protein gain due to muscle formation, or protein loss due to muscle degeneration.

Definition
nitrogen
Term

 

 

      The anabolic hormones ____________________ and ____________________ are especially active in skeletal muscle growth during puberty in both girls and boys.

Definition
growth hormone, sex steroids
Term

 

The macronutrient triglycerides are formed from a 3 carbon molecule called____________________ and three ____________________.

Definition
glycerol, fatty acids
Term

The term____________________ means that molecules like triglycerides do not interact with water and remain separate in solution.

Definition
hydrophobic
Term

A(n) ____________________ fatty acid has one double bond and a ____________________ fatty acid has 2 or more double bonds.

Definition
monounsaturated, polyunsaturated
Term

 

A(n) ____________________ fatty acid does NOT have any double bonds.

Definition
saturated
Term

Both ____________________ acid and ____________________ acid are essential fatty acids.

 

Definition
linolenic, linoleic
Term

 

____________________ is a lipid that is NOT metabolized for energy.

Definition
cholesterol
Term

 

The form of cholesterol that is considered good is _____________ because this lipoprotein transports cholesterol back to the liver.

Definition
HDL
Term

The form of cholesterol that is considered bad is ________________ because this lipoprotein deposits cholesterol into the wall of blood vessels.

 

Definition
LDL
Term

 

Vitamin D helps with absorption of ____________________.

 

Definition
Calcium
Term

 

Vitamin C and the B complex vitamins are ____________ soluble vitamins.

Definition
Water
Term

 

The fat soluble vitamins are vitamin _____, vitamin ___, vitamin ___, and vitamin ____.

Definition
A, D, E, K
Term

 

__________ vitamins are more stable when exposed to heat but are more likely to lead to toxicity when consumed in excess because they are stored in adipose tissue.

Definition
Fat soluble
Term

 

_____________ vitamins are more labile when exposed to heat but are less likely to lead to toxicity when consumed in excess because they are excreted in urine.

 

Definition
water soluble
Term

 

________ serve as coenzymes in many metabolic reactions.

Definition
vitamins
Term

_________ are inorganic substances that are found in bone and serve as electrolytes in the blood.

Definition
Sodium
Term

 

____________ vitamins bind and inactivate free radicals and may delay cellular aging.

 

Definition
anti-oxidant
Term

The main mineral of plasma and interstitial fluid is ____________________ and chloride.

 

Definition
sodium (Na+)
Term

 

The main mineral of the cytoplasm (intracellular fluid) is ____________________ which is balanced by polyvalent anions of proteins.

 

Definition
potassium (K+)
Term

The main mineral needed for strong teeth and bones, skeletal muscle contraction, and neurotransmitter release is __________.

 

Definition
calcium
Term

 

The mineral __________ is needed to form hemoglobin.

Definition
iron
Term

 

The mineral _________ is needed to form thyroid hormones.

 

Definition
iodine
Term

 

A biochemical reaction involving the gain and loss of electrons is call a(n) ____________________ reaction.

Definition
oxidation-reduction
Term

 

The coenzymes ____________________ (nicotinamide adenine dinucleotide) and ____________________ (flavin adenine dinucleotide) are electron acceptors.

 

Definition
NAD+, FAD
Term

Formation of ATP can occur by direct attachment of phosphate to the molecule called ____________________ phosphorylation and ____________________ phosphorylation which involves passing electrons down the electron transport system.

Definition
substrate, oxidative
Term

The ____________________ produces reduced coenzymes through a cyclic process of sequential steps from joining oxaloacetic acid (OAA) to acetyl CoA.

 

Definition
Kreb's cycle
Term

 

____________________ is the initial process of glucose catabolism and involves the formation of two molecules of pyruvic acid in the presence of oxygen.

Definition
glycolsis
Term

 

Energy releasing reactions are referred to as ____________________ metabolism if they require the presence of oxygen.

Definition
aerobic
Term

 

Energy releasing reactions that do NOT require the presence of oxygen are referred to as __________.

Definition
anaerobic
Term

The chemical ____________________ is produced from glucose in the absence of oxygen.

 


Definition
lactic acid
Term

 

The transitional phase (transfer reaction) brings pyruvic acid into the mitochondria as ____________________.

Definition
acetyl-coa
Term

 

The ____________________ recaptures enegy of reduced coenzymes as ATP in the presence of oxygen.

Definition
electon transport systems (ETS)
Term

 

The final electron acceptor in oxidative phosphorylation is ____________________.

 

Definition
oxygen (O2)
Term

 

Formation of "new" glucose from glycerol or amino acids is ____________________.

 

Definition
gluconeogensis
Term

____________________ refers to the break down of glycogen.

 

Definition
glycogenolysis
Term

 

____________________ refers to the formation of glycogen.

 

Definition
glycogenesis
Term

 

The break down of lipids in adipose tissue is ____________________.

 

Definition
lipolysis
Term

 

The formation of lipids in adipose tissue is ____________________.

 

Definition
lipogenesis
Term

 

The liver produces ketones through ____________________ to help other tissues metabolize fatty acids.

 

Definition
ketogenesis
Term

 

The process of metabolizing fatty acids for energy is called ____________________.

 

Definition
beta oxidation
Term

The transfer of an amine from a non-essential amino acid to form a different non-essential amino acid is ____________________.

 

Definition
transamination
Term

 

The process of metabolizing amino acids for energy is called ____________________.

 

Definition
oxidative deamination
Term

 

Utilizing amino acids results in the production of the metabolic waste ____________________ from ammonia and carbon dioxide.

Definition
urea
Term

 

The liver produces most of the ____________________ proteins found in blood.

Definition
plasma
Term

 

The liver processes molecules through ____________________ to generally render them less toxic.

Definition
biotransformation
Term

 

The liver is involved with activation of vitamin ____________________.

 

Definition
D
Term

 

The liver stores glucose in the form of ____________________.

 

Definition
glycogen
Term

 

The liver stores ____________________ attached to ferritin.

 

Definition
iron
Term

 

The lipoprotein ____________________ is referred to as “bad” cholesterol because it deposits cholesterol and triglycerides in the blood vessel wall.

Definition
LDL
Term

 

The lipoprotein ____________________ is referred to as “good” cholesterol because it returns cholesterol and triglycerides to the liver.

Definition
HDL
Term

 

Both ____________________ and ____________________ are hormones produced by pancreatic islets.

 

Definition
insulin, glucagon
Term

 

The hormone ____________________ is associated with the absorptive state and triggers the uptake of glucose by body cells.

 

Definition
insulin
Term

 

The hormone ____________________ is associated with the postabsorptive state and triggers mechanisms to help conserve glucose and generate alternate metabolic pathways to maintain glucose levels.

Definition
glucagon
Term

 

The ____________________ is a measurement for overweight and obese that takes into account a person’s height and weight.

Definition
Body mass index (BMI)
Term

 

The ____________________ is the resting metabolism of an individual associated with limited energy expenditure.

Definition
basa metabolic rate (BMR)
Term
The anerobic process fro breaking down glucose into pyrovic acid is
Definition
glycolysis
Term
______, the formation of triglycerides, occurs when cellular ATP and glucose levels are high.
Definition
lipogensis
Term
Pro-Drugs
Definition

initially inactive and exert no pharmacological effects until they are metabolized

 

 

 

Term
Metabolism
Definition
Converts fat-soluble drugs into water-soluble metabolites. The method by which drugs are inactivated or bio-transformed by the body. Active drugs is changed into inactive metabolites then excreted.
Term
Additive effects
Definition
(Drug-Drug Interaction)
Occurs when 2 drugs with similar pharmacological actions are taken.
Term
Synergism
Definition
(Drug Drug Interactions)
Occurs when 2 Drugs with different sites or mechanisms of action produce greater effects when taken together.
Term
Interference
Definition
(Drug-Drug Interactions)
One drug interfers with the metabolism of a second drug. May lead to intensified effects of the second drug.
Term
Displacement
Definition
(Drug-Drug Interaction)
A drug with a strong attraction to protein binding sites may displace a less tightly bond drug. May increase the effects of the displaced drug.
Term
What are the factors that affect drug metabolism?
Definition
Enzyme induction and Enzyme inhibition
Term
Where are Drug-metabolizing enzymes located?
Definition
Kidneys, liver, red blood cells, plasma, lungs, gastrointestinal mucosa.
Term
What is the most important guide for pediatric drug therapy?
Definition
Child's age, weight, and level of growth and development.
Term
"Five Rights"
Definition
drug, dose, patient, route, time
Term
Agonist
Definition
drugs that produce a response. Accelerate or slow down normal cellular processes. Similar effects as naturally produced hormones.
Term
What are the characteristics of a receptor?
Definition
Activates a drug. Protiens and drugs bind to affect a target affect. All body cells do not respond to all drugs. Drug molecules must occupy a minimal number of receptors to produce pharmacological effect.
Term
Antagonists
Definition
Drugs that block response, inhibit cell function.
Term
Bio-availability
Definition
(Subcategory of Absorption)
the percentage of a drug that reaches systemic circulation
Term
First-Pass effect
Definition
the process in which a drug passes to the liver first.
Term
Scheduler I
Definition
MOST easily abused.
NOT approved for medical use, NOT therapeutic. EXP: Rohypnol, Lysergic Acid Diethylamide (LSD), and Heroin.
Term
Pharmacokinetic
Definition
The process of drug movement to achieve drug action: Absorption, Distribution, Metabolism, and Excretion.
Term
Prototypes
Definition
Individual drugs that represent groups of drugs. Often the first drug of a particular group to be developed. EXP: Morphine is the prototype of Opioid analgesics.
Term
Local
Definition
Act mainly on the site of application
Term
Systemic
Definition
Taken into the body circulated via the blood stream to sites of action, and eventually eliminated from the body.
Term
Trade Name
Definition
Brand Name given by the manufacturer. patented and Capitalized.
Term
Absorption
Definition
The process that occures from the time a drug enters the body to the time it enters the bloodstream to be circulated. Factors that affect the rate and extend the drug absorption are: Dosage form, route and administration, administration site,blood flow, and GI function.
Term
Distribution
Definition
The transport of drug molecules withing the body. Drugs are carried by blood and tissue fluids to: Action sites, metabolism sites, excretion sites. Depends on adequacy of blood circulation. After absorption it is affected by: Albumin protein binding, blood brain barrier, pregnancy, and lactation.
Term
What are controlled drugs and guidelines for scheduling?
Definition
Narcotics, stimulants, depressants, hallucinogens, and anabolic steroids. Store in locked containers.
Term
Generic Name
Definition
Official name from the company that did the research and development and received initial approval from the FDA. Often related to chemical compound. Ending suggest classification "cillin"
NOT capitalized.
Term
What are the best ways to study for pharmacology?
Definition
(best)TEXTBOOK
drug reference book- use in clinical practice
journal articles
select internet sites.
Term
Schedule V
Definition
LEASE potential for abuse, contains moderate amounts of controlled substances. Regulated by lay. May dispense without a prescription. Records kept. EXP: Lomotil and Codeine
Term
Schedule IV
Definition
Used therapeutically. Less potential for abuse
EXP: Phenobarbital and benzodiazepines (Valium ect).
Term
Schedule II
Definition
HIGH potential for abuse, cannot be refilled, used therapeutically, dependance. EXP: morphine, oxycodone, methamphetamine, ritalin, and pentobarbital
Term
Schedule III
Definition
LESS ABUSE potential, used therapeutically, may lead to psychological or physical dependency. EXP: anabolic steroids, ketamine, mixtures with small amounts of opiates.
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