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Nutrition Final
comprehensive
82
Science
Undergraduate 1
12/16/2008

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Term
Nutrition
Definition
The science of how living organisms obtain and use food to support processes required for life
Term
Nutrient
Definition
A substance in foods used by the body to serve one or more of the following purposes:

- Provide a source of energy
- Provide structure
- Regulate Chemical Reactions
Term
Zoonutrients
Definition
A substance found in animal foods and thought to benefit human health (above and beyond the provision of essential nutrients and energy)
Term
Organic
Definition
Plant and animal foods that have been grown, harvested, and processed without conventional pesticides, fertilizers, growth promoters, bioengineering, or ionizing radiation.
Term
Phytochemicals
Definition
A substance found in plants and thought to benefit human health (above and beyond the provision of essential nutrients and energy.)
Term
Functional Foods
Definition
A food that contains an essential nutrient, phytochemical, or zoonutrient and that is thought to benefit human health
Term
Essential Nutrient
Definition
A substance that must be obtained from the diet, because the body needs it and cannot make it in required amounts
Term
What is the preferred source of energy in the body?
Definition
Carbohydrates
Term
What is the water content of the body?
Definition
- 50-65%
- 42 liters for an adult man
Term
How many kCal per gram of FAT?
Definition
9
Term
How many kCal per gram of Carbohydrate?
Definition
4
Term
How many kCal per gram of protein?
Definition
4
Term
The Scientific Method
Definition
Steps used by scientists to explain observations
Term
Placebo
Definition
A "fake" treatment given to the control group that cannot be distinguished from the actual treatment
Term
Control Group
Definition
A group of people, animals, or cells in an intervention study that do not recieve the experimental treatment
Term
Experimental Group
Definition
A group of subjects that are exposed to the variable of an experiment
Term
Random Assignment
Definition
When study participants have an equal chance of being assigned to each experimental group
Term
Anion
Definition
an ion that has a net NEGATIVE charge
Term
Cation
Definition
An ion that has a net POSITIVE charge
Term
Confounding Variables
Definition
A factor, other than the one of interest, that might influence the outcome of the experiment
Term
Octet Rule
Definition
The "desire" of an atom to have eight electrons in its outer valence shell
Term
What is the normal pH of blood?
Definition
7.4
Term
Buffer
Definition
A substance that releases or binds hydrogen ions in order to resist changes in pH
Term
What is the primary cause of ulcers?
Definition
A bacteria called H. Pylori
Term
Simple Carbohydrates
Definition
- a.k.a. simple sugar
- category of carbohydrates consisting of mono- or disac- charides
Term
Complex Carbohydrates
Definition
Category of carbohydrates that includes oligosaccharides and polysaccharides
Term
Glycogen
Definition
Polysaccharide consisting of a highly branched arrangement of glucose molecules found primarily in liver and skeletal muscle
Term
Why is fiber indigestible?
Definition
Because they contain beta-glycosidic bonds, which are resistant to digestive enzymes
Term
Glycemic Response
Definition
The impact of different foods on the magnitude and duration of the rise in blood glucose after a meal
Term
Insulin
Definition
Hormone secreted by the pancreatic beta-cells in response to increased blood glucose
Term
Glucagon
Definition
Hormone secreted by the pancreatic alpha-cells in response to decreased blood glucose
Term
Pancreas
Definition
Releases pancreatic juice that neutralizes chyme and contains enzymes needed for carbohydrate, protein, and lipid digestion.
Term
Amino Acid Structure
Definition
- Building blocks of proteins
- nutrient composed of a central carbon bonded to an amino group, carboxylic acid and an R-group
Term
Ketones
Definition
Organic compound used as an energy source during starvation, fasting, low-carbohydrate diets, or uncontrolled diabetes
Term
Protein Quality
Definition
The adequacy of food proteins for supplying the body with essential amino acids
- Bioavailability and completeness are factors
Term
What happens to excess protein?
Definition
They are converted to lipids via deamination
Term
Marasmus
Definition
- protein-energy malnutrition
- All out starvation
- skin and bones appearance
Term
Kwashiorkor
Definition
- What the first child gets when the second child comes
- Slight energy deficiency with significant protein deficiency
- Puffed bellies
Term
Primary Protein Structure
Definition
- Order/Organization of the amino acids
- Determined by DNA
- Unique
- Determines the proteins major characteristics
- one variation can cause disease
- sickle cell anemia
Term
Secondary Protein Structure
Definition
- Three-dimensional shape
- created by +/- charges of the amino and carboxylic acids
- Form weak hydrogen bonds
- most common structures:
- alpha helix
- beta folded sheets
Term
Tertiary Protein Structure
Definition
- Additional Folding of the protein due to R-groups
- Form disulfide bonds
- very strong
- disrupting them can ruin the structure
Term
Quarternary Protein Structure
Definition
- Several polypeptide chains that come together to form a final protein
- can have non-protein parts called prosthetic groups
- are essential to the protein's function
Term
Steps of Protein Synthesis
Definition
1. Cell-Signaling
- a cell receives a signal that tells it to make a protein

2. Transcription
- mRNA copies the DNA to bring it out of the nucleus

3. Translation
- tRNA reads the mRNA and determines what amino acids to put in the new protein
Term
Oils
Definition
Lipids that are liquid at room temperature
Term
Fats
Definition
Lipids that are solid at room temperature
Term
What is "alpha" in relation to fatty acids?
Definition
The end of a fatty acid with the carboxylic acid group (-COOH)
Term
What is "omega" in relation to fatty acids?
Definition
The end of a fatty acid with the methyl group (-CH3)
Term
Trans Fats
Definition
- A fatty acid containing at least one trans double bond
- Can be created through a process called hydrogenation
Term
What are the essential fatty acids?
Definition
Linolenic (omega 3) and Linoleic (omega 6)
Term
Cholesterol
Definition
- lipid class of sterols/sterol esters
- multiring structures
- weak polar compound
Term
HDL
Definition
- “Good” cholesterol
- Lipoprotein made by liver that circulates in the blood to collect excess cholesterol from cells
- Lowest lipid-to-protein ratio
- Reverse cholesterol transport
- Salvages excess cholesterol from cells and transports them back to liver
Term
LDL
Definition
- “Bad” cholesterol
- Delivers cholesterol to cells
- Can increases build-up of plaque
- High levels of LDL associated with increased risk for cardiovascular disease
Term
Micelles
Definition
- Smaller stable lipid particles
- Increase surface area of lipid
Term
What are the 10 water soluble vitamins?
Definition
Riboflavin B2
Niacin B3
Pantothenic Acid B5
B6
B12
C
Biotin
Choline
Folate
Thiamin
Term
Which amino acid can niacin be made from?
Definition
Tryptophan
Term
What are the fat-soluble vitamins?
Definition
Vitamin A
Vitamin E
Vitamin D
Vitamin K
Term
What metabolite in skin is used to synthesize vitamin D3?
Definition
Cholesterol
Term
Gallbladder
Definition
- Where Bile is stored
- Stimulated by Cholecystokinin
- Releases bile into the small intestine
Term
Small intestine
Definition
- Primary site of chemical digestion and nutrient absorption
- 20 ft. Long
- Order of parts:
- Duodenum
- sphincter of Oddi
- Jejunum
- Ileum
Term
Epiglottis
Definition
The cartilage flap that covers the trachea for swallowing
Term
Esophogus
Definition
Transports food from the pharynx to the stomach
Term
What is the order of the GI sphincters (top to bottom)?
Definition
- Gastroesophageal
- Pyloric
- Sphincter of Oddi
- Ileocecal
- Anal
Term
Peristalsis
Definition
Waves of muscular contraction that move materials in the GI tract in a forward direction
Term
Segmentation
Definition
A muscular movement in the GI tract that moves the contents back and forth within a small region
Term
What is the order of the sections of the GI tract (top to bottom)?
Definition
Mouth --> Esophogus --> Gastroesophogeal Sphincter --> Stomach --> Pyloric Sphincter --> S.I. Duodenum --> Sphincter of Oddi --> Jejunum --> Ileum --> Ileocecal Sphincter --> Large Intestine --> Anal Sphincter
Term
What are the phases of digestion?
Definition
Cephalic
- before food enters mouth
Gastric
- arrival of food in stomach
Intestinal
- from the small intestine on
Term
Monosaccharides
Definition
Carbohydrate consisting of a single sugar
Term
Thiamin
Definition
Water Soluble

Function: ATP production
Coenzyme: TPP
Deficiency: Beri Beri
Symptoms: dry, wet, infintile, cerebral
Term
Riboflavin (B2)
Definition
Water Soluble

Function: converts vitamins
Coenzyme: FAD
Deficiency: Ariboflavinosis
Symptoms: weakness, sores of the lips, inflamed tongue, anemia, confusion
Term
Niacin (B3)
Definition
Water Soluble

Function: DNA synthesis, replication, and repair
Enzyme: NAD+ / NADP+
Deficiency: Pellagra
Symptoms: rough skin, dermatitis, dementia, diarrhea, death
Term
Pantothenic Acid (B5)
Definition
Water Soluble

Function: Metabolism of glucose, amino acids, fatty acids, for energy
Enzyme: CoA
Deficiency: Burning Feet Syndrome
Symptoms: tingling in the feet, limbs, fatigue, weakness, nausea
Term
Vitamin B6
Definition
Water Soluble

Function: Over 100 chemical reactions related to the metabolism of proteins and amino acids via transamination
Enzyme: PLP
Deficiency: Microcytic Hypochromic Anemia
Symptoms: small, lightly colored red blood cells
Term
Biotin
Definition
Water Soluble

Function: energy metabolism
Enzyme: HCO3
Deficiency: no name
Symptoms: depression, hallucinations, skin irritations, infections, hair loss, poor muscle control, seizures, developmental delays in infants.
Term
Folate
Definition
Water Soluble

Function: transfer of single carbon groups
Enzyme: THF
Deficiency: Macrocytic Anemia
Symptoms: immature red blood cells
Term
Vitamin B12
Definition
Water Soluble

Function: CoA and THF production
Enzyme: THF
Deficiency: Pernicious Anemia
Symptoms: macrocytic anemia, difficulty sleeping, numbness, memory loss, severe neurological disturbances
Term
Vitamin C
Definition
Water Soluble

Function: Antioxidant
Enzyme: --
Deficiency: Scurvy
Symptoms: bleeding gums, skin irritations, bruising, poor wound healing.
Term
Choline
Definition
Water Soluble

Function: Synthesizing phospholipids
Deficiency: Liver Damage in adult men
Term
Vitamin A
Definition
Fat Soluble

Function: Growth, Reproduction, Vision
Parent Compound: Retinoids
Dificiency: VADD
Symptoms: night blindness
Term
Vitamin D
Definition
Fat Soluble

Function: Calcium Homeostasis, Bone Health, Cell differentiation
Parent Compound: Calciferols
Deficiency: Rickets
Symptoms: Osteomalacia, Osteoperosis
Term
Vitamin E
Definition
Fat Soluble

Function: Antioxidant, Cell membranes, Eye health, Heart health
Parent Compound: tocopherol
Deficiency: Neromuscular problems, Hemolytic anemia
Term
Vitamin K
Definition
Fat Soluble

Function: Coenzyme, Blood clotting, bone helth, tooth health
Parent Compound: quinones
Deficiency: vitamin K deficiency
Symptoms: bleeding
Term
Trans Double Bond
Definition
A carbon-carbon double bond in which the hydrogen atoms are arranged on opposite sides of the double bond
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