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Nursing 120 Test 5
White Blood Cells
54
Medical
Graduate
10/09/2007

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Cards

Term
Five types of WBCs
Definition
Never Let Mothers Eat Babies;

Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils
Term
Hematology
Definition
Study of blood and blood forming tissues
Term
Blood cell production is called
Definition
Hematopoiesis
Term
Where are WBCs made and in what type of tissue
Definition
Flat and irregular bones; red bone marrow
Term
Three functions of blood
Definition

Transportation, Protection, and Regulation

Term
Two major components of blood and % composition
Definition
Plasma is 55%

Blood cells (formed elements) are 45%
Term
Components and Percent breakdown of Plasma
Definition

Water 91%

Protein 7%

Other solutes 2% 

Term
Name the protein types in Plasma and their % composition
Definition
Albumin 58%

Globulin 38%

Fibrinogen 4%
Term
What is Serum
Definition
Plasma without clotting factors (fibrinogen)
Term
Alternate name for WBCs
Definition

Leukocytes

Term
Two subcategories of Leukocytes
Definition
Granulocytes (polymorphonuclear leukocytes)

Agranulocytes (Mononuclear cells)
Term
Name the Granulocytes
Definition
Neutrophils

Eosinophils

Basophils
Term
Name the Agranulocytes
Definition
Lymphocytes

Monocytes
Term
Name the normal range for neutrophils
Definition
Neutrophils 0.50 - 0.78
Term
Normal range for Lymphocytes
Definition
0.20 - 0.40
Term
Normal range for Monocytes
Definition
0.04 - 0.08
Term
Normal range for Eosinophils
Definition
0.0 - 0.04
Term
Normal Range for Basophils
Definition

0.0 - 0.02

Term
Normal range for Leukocytes
Definition
4.0 - 11.0
Term

What do neutrophils do

Definition
Phagocytosos in early stages of inflammation
Term
What do Eosinophils do
Definition

Some phagocytosis

They engulf antigen/antibody complexes formed during allergic response

They defend against parasite infections

Term
What do basophils do
Definition
Limited phagocytosis

Release heparin, serotonin, and histamine
 in response to allergic and inflammatory reactions.
Term
What do lymphocytes do
Definition

Immune response for specific invaders

B-cells, T-cells, and Natural Killer cells?

Term
What do monocytes do
Definition
potent phagocytic cells

become macrophages upon entering tissue/leaving vessels

cellular immune response (working with Lymphocytes)
Term
What are Bands and Segs; what is shift to left/right
Definition
Bands are immature neutrophils (high # = shift to left)

Segs are mature neutrophils (high # = shift to right)

Term
Leukopenia
Definition
Low WBCs
Term
Neutropenia
Definition
Low Neutrophils
Term
Pancytopenia
Definition
Low counts on all blood cells
Term

thrombocytes and where do they come from

Definition
platelets come from megakaryocytes
Term
Primary function of the Lymph system
Definition
carries proteins, fat, and certain hormones
from GI tract back to the blood

Returns pale yellow lymph fluid from interstitial spaces back to the blood via lymphatic capillaries, ducts, and lymph nodes
This prevents edema
Term

What are lymph nodes and what is their primary function

Definition
They are aggregations of lymph tissue
(200 or so throughout body)

filtration of pathogens and foreign particles from lymph fluid

Produce Lymphocytes and Monocytes
Term
where is the spleen and what does it do
Definition

LUQ

Four functions:

     Hematopoiesis (in fetal development)


     Filtration (removes RBCs, recycles iron, catches bacteria)


     Immunologic (Produces Lymphocytes and Monocytes)


     Storage (stores RBCs and 30% of platelets)

Term
Abnormal Lymph node palpation findings
Definition
Enlarged (Larger than 1 cm and/or continuous enlargement)

fixed position (not mobile)

Hard

Tender
Term
Would you die if you had your spleen removed?
Definition

No; it is not a vital organ

You may, however, have some issues with bilirubin processing and with immune function since the spleen processes old RBCs and makes Lymphocytes and Monocytes

Term
what is a differential WBC count
Definition

a differential count gives the percentage of each type of WBC in the total WBC count

Term
Can the WBC count be normal
while having an abnormal differential count?
Definition

YES, you may have low neutrophils
and high monocytes or Lymphocytes...
while the total WBC count is normal (4 - 11 thousand)

Term
Significance of high and low WBC count
Definition
High:
Inflammatory and infectious process, leukemia

Low:
Aplastic anemia, side effect of chemotherapy and irradiation
Term
Significance of high and low Segmented Neutrophils
Definition

High:
bacterial infections, collagen diseases, Hodgkin's Lymphoma


Low:

Aplastic anemia, viral infections

Term
Significance of high and low Band Neutrophils
Definition
High:
Acute infections

Low:
can't be lower than 0
Term
significance of high and low Lymphocytes
Definition
High:
Chronic infections, lymphocytic leukemia, mononucleosis, viral infections

Low:
Corticosteroid therapy, whole-body irradiation
Term
Significance of high and low Monocytes
Definition
High:
Acute infections, chronic inflammatory disorders, Hodgkin's Lymphoma, Malaria, Monocytic leukemia

Low:
Can't really be lower than 0.04
Term
Significance of high and low Eosinophils
Definition
High:
Allergic reactions, eosinophilic and chronic granulocytic leukemia, Hodgkin's Lymphoma, parasitic disorders

Low:
Corticosteroid therapy
Term
Significance of high and low Basophils
Definition
High:
Hypothyroidism, myeloproliferative diseases, ulcerative colitis

Low:
Hyperthyroidism, stress
Term

Thrombocytosis

Definition
High platelet count
Term
Does WBC count go up or down as we age?

Is there an increased response to infection with age?
Definition

WBC count does not change with age

But, there is a lowered response to infection

Term
Where is the thymus and what does it do?
Definition
It is behind the upper part of the sternum above the haart

It functions in the immune system, especially early in life

As we age the thymus shrivels up 
Term
what happens to platelet counts, fibrinogen, and Partial Thromboplastin Time as we age?
Definition
Platelet counts do not change


Fibrinogen goes up


This doesn't increase Partial Thromboplastin Time though, that declines
Term

Are the elderly more likely to develop hemorages or blood clots?

Definition
Clots
Term

What is a biopsy

name two types specific to this chapter

Definition

Biopsy is the surgical extraction of tissues for examination
often used to determine presence and/or type of cancer

Bone Marrow and Lymph Node biopsies

Term
Prefered sites for bone marrow biopsy
Definition
posterior iliac crest

anterior iliac crest and sternum are alternate sites



Term
Two parts of bone marrow examination
Definition
Aspiration: the taking (aspiring) of a sample of bone marrow

Biopsy: examination of the removed marrow sample

Note: bone can also be removed and biopsied;
requires special cutting tool with T-handle
Term
Nursing implications of bone marrow biopsy
Definition

painful for client;
explain proceedure and administer strong analgesics

Hemostasis:
apply pressure to site (possibly 30-60 minutes if bleeding)
patient lays on side of puncture

Term
Two types of Lymph Node Biopsy
Definition
Open:
open surgery

Closed:
fine needle aspiration
Term
Nursing implications for Lymph Node Biopsy
Definition
Not much really

possibility of insidious bleeding
apply direct pressure

monitor vitals
watch for infection
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