Term
|
Definition
HCTZ (HydroDiuril)
Metolazone (not truly thiazide but work like the thiazides) |
|
|
Term
|
Definition
| Blocks reabsorption of sodium and chloride in early segment of distal convoluted tubule |
|
|
Term
|
Definition
| there is maximum amount of increased output that can occur |
|
|
Term
|
Definition
| cannot be used to promote fluid loss in patients with severe renal failure |
|
|
Term
|
Definition
| Decrease BP by decreasing blood volume (decreases pre-load) and decreasing peripheral vascular resistance (decreases afterload) |
|
|
Term
|
Definition
| produce dieresis about 2 hrs after given and peak 4-6 hrs; last 12 hours |
|
|
Term
|
Definition
| often the first drug used to treat HTN |
|
|
Term
| Thiazide and Loop Diuretics |
|
Definition
| teach pt to increase intake of K+ rich foods |
|
|
Term
| Thiazide and Loop Diuretics |
|
Definition
| pts who take Digoxin are at risk for Digitalis toxicity if develop low K+levels |
|
|
Term
| Thiazide and Loop Diuretics |
|
Definition
| monitor BS level in diabetics and teach them to control BS more judiciously |
|
|
Term
| Thiazide and Loop Diuretics |
|
Definition
| monitor BS level in diabetics and teach them to control BS more judiciously |
|
|
Term
| Thiazide and Loop Diuretics |
|
Definition
| hypokalemia,increased blood sugar levels, can precipitate gout, can precipitate diabetes |
|
|
Term
|
Definition
| can cause loss of Na, Cl and water, but not to extent that loop diuretics do |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
Furosemide (Lasix)
Bumetanide (Bumex)
Torsemide (Demadex) |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| Act in the Loop of Henle to block reabsorption of sodium and chloride |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| powerful diuretic and usually reserved for situations that require rapid mobilization of fluid-pulmonary edema, hepatic failure, renal failure |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| for use in HTN not controlled by other diuretics |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| can produce diuresis even when GFR and renal blood flow are low |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| can be given orally where produce diuresis w/in 1 hr and last 6-8 hrs; given IV onset of action is 5 minutes and duration of action is 2 hrs. |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| use with caution with other drugs that are ototoxic |
|
|
Term
| High ceiling Loop Diuretics |
|
Definition
| with twice daily dosing can produce nocturia; take second dose as early as possible |
|
|
Term
|
Definition
| NSAIDS can decrease effectiveness of |
|
|
Term
|
Definition
Spironolactone (Aldactone)
Triamterene (Dyrenium) |
|
|
Term
|
Definition
| blocks action of Aldosterone in distal tubule to promote retention of K+ and excretion of Na+; |
|
|
Term
|
Definition
| produces minimal diuresis |
|
|
Term
|
Definition
| effects take up to 48 hours to be apparent |
|
|
Term
|
Definition
| commonly used in conjunction with thiazide or Loop diuretic for HTN or edema |
|
|
Term
|
Definition
| produces minimal reduction in blood volume |
|
|
Term
|
Definition
-teach pt to limit K+ rich foods in diet
-pt should not use K+ salt substitutes |
|
|
Term
|
Definition
| use only with ACEI and ARB when absolutely needed |
|
|
Term
|
Definition
| is available mixed with a thiazide (Aldactazide) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| produces gynecomastia in males and impotence and menstrual irregularities and hirsutism in females |
|
|
Term
|
Definition
| may cause n/v, leg cramps, dizziness |
|
|
