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Nuerologic disorders
Linton
153
Nursing
Undergraduate 1
06/26/2023

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Term
Axons of one neuron doesn’t touch the _ of another
Definition
dendrites
Term
When an impulse reaches the end of its axon, a biochemical messenger called a _ is released
Definition
neurotransmitter
Term
glucose of CSF
Definition
40 to 70 mg/dL
Term
csf is composed of
Definition
water, glucose, electrolytes, proteins, <5 wbc
Term
normal protein level of CSF
Definition
100 mg/dL
Term
Extends from the border of the first cervical vertebra (C1) to the level of the second lumbar vertebra (L2)
Definition
the spinal cord
Term
aging pigment deposited in nerve cells with amyloid, a type of protein
Definition
lipofuscin
Term
which convey impulses towards the cell body
Definition
Dendrite
Term
which conduct impulses away from the cell body
Definition
Axon
Term
Transmit information from distal parts of the body or environment toward the central nervous system
Definition
Sensory neurons (Afferent)
Term
Carry motor information from the CNS to the periphery
Definition
Motor neurons (Efferent)
Term
material that covers many axons and dendrites, and enhancees conduction along nerve fibers
Definition
myelin sheath
Term
myelin sheath gives the axons a _ appearance, cell bodies without myelin appear _
Definition
white, gray
Term
vital signs in a neurological assessment are a reliable but
Definition
late sign
Term
5 categories of an advanced neurologic examination
Definition
cranial nerves, coordination and balance, neuromuscular function, sensory function, reflexes
Term
OH OH OH TO TOUCH AND FEEL A GIRL'S VELVET SO HEAVENLY TRY IT
Definition
Olfactory, optic, oculomotor, trochlear, trigeminal, abducens, facial, acoustic, glassopharyngeal, vagus, spinal accessory, hypoglossal
Term
drug therapy for the neurologic system
Definition
Antimicrobials
Analgesics
Anti-inflammatory
Corticosteroids
Anticonvulsants
Diuretics
Chemotherapeutic agents
Dopaminergics
Anticholinergics
Cholinergics
Antihistamines
Term
Any procedure done to repair a skull defect
Definition
Cranioplasty
Term
Excision of a segment of the skull
Definition
Craniectomy
Term
Surgical opening of the skull
Definition
Craniotomy
Term
Monitor for s/sx of complications of brain surgery
Definition
Headache
Visual disturbance
Vomiting
Seizure
Respiratory distress or depression
For craniotomy: increased ICP, CSF leak, meningitis, & seizures
Term
gillain barre syndrome typically begins
Definition
at the feet and works up
Term
normal ICP
Definition
0-15 mm Hg
Term
earliest and most reliable indicatro of ICP
Definition
LOC
Term
Classic pupil changes (late sign): With increased ICP
Definition
pupils dilated, fixed, non-reactive to light (referred to as “blown pupils”) due to pressure on the oculomotor (3rd) cranial nerve
Term
symptoms of icp
Definition
contralateral effects, hemiparesis, hemiplegia, decerebrate, decorticate, hypothalamic impariment, hypertension, widen pulse pressure, HR slow & irregular, alterations in resp pattern
Term
extension posturing, problem in midbrain/upper pons
Definition
decerebrate
Term
abnormal flexion posturing, problem is above the midbrain
Definition
decorticate
Term
drug therapy for increased ICP
Definition
Mannitol (hyperosmolar diuretic)
Corticosteriods to decrease inflammation
Decadron or Solumedrol
Term
Intracranial vasoconstriction followed by vasodilation
Definition
migraine headache
Term
migraine headache is Triggered by
Definition
menstruation, ovulation, alcohol, some foods, stress
Term
pain r/t to migraine headache is usually _ and often beings in the _ area and is very intense
Definition
unilateral, temple or eye
Term
mild migrains are treated with
Definition
acetominophen or aspirin
Term
sever migraines are treated with
Definition
ergotamine (Cafergot) or sumatriptan (Imitrex) tablet or autoinjector for self-injection, fluids, and rest
Term
s&s of migraine headache
Definition
tearing and n/v, hypersensitive to light and sound
Term
Occur in a series of episodes followed by a long period with no symptoms
Definition
Cluster Headache
Term
Cluster Headaches are
Definition
Intensely painful, usually unilateral, and seem to be related to stress or anxiety
Usually have no warning symptoms
Shorter duration than migraines
Term
treatment for cluster headache may include
Definition
cold application, indomethacin (Indocin), and tricyclic antidepressants
Term
Result from prolonged muscle contraction from anxiety, stress, or stimuli from other sources, such as a brain tumor or an abscessed tooth
Definition
Tension Headache
Term
s&s of tension headache
Definition
Pain location may vary; may have nausea and vomiting, dizziness, tinnitus, or tearing
Term
treatment for tension headache
Definition
correction of known causes, psychotherapy (if related to anxiety), massage, heat application, and relaxation techniques
Analgesics, usually nonopioid, and anxiolytics to reduce anxiety and stress may be prescribed
Term
types of head injuries
Definition
scalp injuries, concussion, contusion, hematoma, intracerbral hemorrhage, penetrating injuries
Term
scalp injuries
Definition
Lacerations, contusions, abrasions, and hematomas
Term
Trauma with no visible injury to the skull or brain
Definition
concussion
Term
Bruising and bleeding in the brain tissue
Definition
contusion
Term
Subdural hematoma or epidural hematoma
Definition
hematoma
Term
From lesions within the tissue of the brain itself
Definition
intracerebral hemorrhage
Term
Sharp objects penetrate the skull and brain tissue
Definition
penetrating injuries
Term
surgical treatment of head injury are directed at
Definition
evacuating/remvoing hematomas and debriding damaged tissue
Term
Inflammation of the meningeal coverings of the brain and spinal cord caused by either viruses or bacteria
Definition
Meningitis
Term
Three most frequently encountered acute bacterial meningitis are:
Definition
Neisseria meningitis (meningiococcal)
Streptococcus pneumoniae (in adults)
Haemophilus influenzae
Term
mode of transmissin for meningitis
Definition
droplets
Term
Complications of meningitis include
Definition
seizures, septicemia, vasomotor collapse (shock), and increased ICP
Term
s&s of menigitis
Definition
Headache “Worst of my life”
Nuchal rigidity
Irritability; Altered LOC
Decreased level of consciousness
Photophobia (sensitivity to light)
Hypersensitivity; Seizures
Positive Kernig’s sign
fever
signs of increased ICP
positive brudzinski's sign
Term
When pt’s hip is flexed to a 90o angle producing pain in the hamstring area when knee is extended
Definition
positive kernig's sign
Term
Flexion of Both hips when the neck is flexed
Definition
positive brudzinski's sign
Term
medical diagnosis for menigitis
Definition
Lumbar puncture to obtain CSF for lab analysis
Term
medical treatment for menigitis
Definition
atimicrobial therapy, anticonvulsans, osmotic diuretis
Term
narcots are usually contraindicated for meningitis because they may
Definition
interfere with accurate neurological assessment
Term
patient's with meningits and those who interact with them should recieve the following interventions as necessarry
Definition
vaccination to preven pneumoccocal pneumonia and influenza
treatment of respiratory and ear infections,
prophylactic antibiotics for anyone in close contact with bacterial meningitis
Term
Inflammation of brain tissue itself. Usually caused by a virus
Definition
encephalitis
Term
s&S of encephalitis
Definition
Fever, nuchal rigidity (stiff neck), headache, confusion, delirium, agitation, and restlessness commonly seen
Comatose or exhibit aphasia, hemiparesis, facial weakness, and other alterations in motor activity
Term
medical treatment for encphalitis
Definition
enhance pt confort & increase strength, take appropriate safety precautions for possible seizure activity
Term
Progressive disease that affects the motor & sensory components of the peripheral nervous system
Definition
Guillain-Barré Syndrome
Term
four types of guillain barre syndrome
Definition
Ascending
Descending
Miller Fisher syndrome
Pure Motor GBS
Term
three stages of guillain barre syndrome
Definition
Initial phase
Plateau phase
Recovery
Term
pt with gullain barre syndrome often report
Definition
recent viral infection or vaccination
Term
Symmetric muscle weakness: begins in lower extremities; ascends to trunk and upper extremities
Definition
intial phase of guillain barre syndrome
Term
intial phase of guillain barre syndrome s&S
Definition
Visual and hearing disturbances, difficulty chewing, and lack of facial expression
Mild paresthesias or anesthesia in feet and hands in a glove or stocking distribution pattern
Term
autonomic NS effects of the initial phase of guillain barre syndrome
Definition
hypertension, orthostatic hypotension, cardiac dysrhythmias, profuse sweating, paralytic ileus, and urinary retention
Term
any disease or malfunction of the automonic nervous system occurs frequently in pt with respiratory involvement and is potentially life-threatening – may require intubation. r/t initial phase of guillain barre syndrome
Definition
Dysautonomia
Term
Remains essentially unchanged; no further deterioration, but no improvement either
Definition
plateau phase of guillain barre syndrome
Term
Remyelinization; muscle strength returns in a proximal-to-distal pattern (head to toes)
Definition
recovery phase of guillain barre syndrome
Term
medical treatment of guillain barre syndrom
Definition
preserve vital function (respiration), closely monitor resp status, mechanical ventilation initiated if vital capacity falls to 15mL/kg of body weight, massive doese of corticosteroids, plasmapheresis
Term
Progressive degenerative disorder of the basal ganglia: an eventual loss of coordination and control over involuntary motor movement
Definition
Parkinson Disease
Term
Idiopathic Parkinson has no cause but linked to decreased levels of _ in the basal ganglia
Definition
dopamine
Term
s&s of parkinson disease
Definition
Tremor, rigidity, and bradykinesia
Loss of dexterity and power in affected limbs, aching, monotone voice, handwriting changes, drooling, lack of facial expression, rhythmic head nodding, reduced blinking, and slumped posture
Advanced disease may have cogwheel rigidity and gait disturbances
Depression common; dementia may develop
Term
assessment findings for parkinson's syndrome
Definition
Weakness, fatigue, muscle cramps, sweating, dysphagia, constipation, difficulty voiding, and unusual movements
Term
when assessing for parkinson's syndrome note
Definition
Note lack of facial expression, eyes fixed in one direction, drooling, slurred speech, tearing, tremors, muscle stiffness, and poor balance and coordination
Term
amyotrophic lateral sclerosis is also known as
Definition
lou gehrig's diseas
Term
Degenerative neurologic disease, Affects males 2-4 times as often as females and strikes most often between 40 and 70 years of age
Definition
Amyotrophic Lateral Sclerosis
Term
withe ALS there is Degeneration of the anterior horn cells and the corticospinal tracts, so patient exhibits
Definition
upper and lower motor neuron symptoms
Term
s&S of ALS
Definition
Weakness of voluntary muscles of the upper extremities, esp. the hands
Difficulty swallowing and speaking with progressive weakness
Respirations shallow; difficulty clearing airway of pulmonary secretions
Death results from aspiration, respiratory infection, or respiratory failure
Term
medical treatment for ALS is
Definition
supportive
Term
symptoms that may be noted when assessing ALS
Definition
dyspnea, dysphagia, muscle cramps, weakness, twitching, joint stiffness, muscle atrophy, abnormal reflexes and gait, and paralysis
Term
Inherited degenerative neurologic disorder that causes a breakdown of nerve cells due to a defect in the 4th chromosome
Definition
Huntington’s Disease
Term
huntignton's disease usually begins in middle adulthood with
Definition
abnormal movement's, emotional disturbance, intellectual decline
Term
symptoms of huntington's diseas progress steadily, increasing disability and death in _ after symptoms begin
Definition
15 to 20 years
Term
Chronic, progressive disease due to a defect at the neuromuscular junction, where impulses are transmitted to muscle tissue
Definition
Myasthenia Gravis
Term
Insufficient acetylcholine receptor sites at the motor nerve junction, resulting in decreased acetylcholine which impairs neuromuscular transmission
With repeated stimulation, the muscle becomes exhausted; eventually unable to contract at all
Definition
myasthenia gravis
Term
if respiratory muscles are involved with myasthenia gravis death from _ occurs
Definition
respiratory insufficienc or arrest
Term
s&s of myasthenia gravis
Definition
Weakness of voluntary muscles, particularly those of chewing, swallowing, and speaking, ptosis
Term
myasthenia gravis show partial improvements of strength with _ and dramatic improvement of strength with the use of _
Definition
rest, anticholinesterase drugs
Term
medical diagnosis of myasthenia gravis involves administering edrophonium, an antichlinerstrerase agent, muscle tone is markedly improved within _ of injections, persists for
Definition
1 minute, 4 to 5 minutes
Term
medical treatment of myasthenia gravis
Definition
anticholinesterase drugs
Corticosteroids
Cytotoxic therapies
Thymectomy
Plasmapheresis
Term
Anticholinesterase drugs
Definition
Neostigmine and pyridostigmine (Mestinon)
Term
(EMERGENCY REQUIRING MECHANICAL VENTILATION) sudden exacerbation of myasthenic symptoms
Definition
Myasthenic Crisis
Term
symptoms of myasthenic crisis
Definition
including difficulty swallowing and breathing, with possible resp arrest
Term
myasthenic crisis is precipitated by undermedicating with _ so they have too little acetylocholine
Definition
anticholinersterase
Term
_ often precipitates events of myasthenic crisis
Definition
infection
Term
(EMERGENCY REQUIRING MECHANICAL VENTILATION) present with sudden, extreme weakness and respiratory impairment
Definition
cholinergic crisis
Term
chlinergic crisis is precipitated by overmedication with _ so they have too much acetylcholine
Definition
anticholinersterase
Term
s&s of cholinergic crisis
Definition
Bradycardia
Generalized weakness or flaccid paralysis
Abdominal cramping; N/V/D
Dyspnea
Diaphoresis
Increased respiratory secretions
No improvement with administration of edrophonium (Tensilon)
Term
s&s of myasthenic crisis
Definition
Restlessness, apprehension
Respiratory muscle weakness; apnea or respiratory arrest develops quickly
Diaphoresis
Dyspnea
Difficulty swallowing
Increased bronchial secretions
Rapid improvement after edrophonium (Tensilon) is administered
Term
A group of neurodevelopmental disorders characterized by difficulties in social interaction and communication, repetitive behaviors, and stereotyped interests and activities
Definition
Autism Spectrum Disorders
Term
autism spectrum disorder includes:
Definition
Classic Autism or Kanner’s syndrome
Asperger’s syndrome
Rett’s syndrome
Childhood disintegrative disorder
Pervasive developmental disorder – not otherwise specified
Term
red flags for diagnosis of autism
Definition
No babbling or pointing by 12 months
No two-word spontaneous phrases by 24 months
Loss of previously attained social or language skills
Term
Developmentally inappropriate degree of gross motor activity, impulsivity, and inattention in the school and home that begins before age 7, lasts more than 6 months, and is not related to any other central nervous system illness
Definition
Attention Deficit/Hyperactivity Disorder
Term
Signs of adhd
Definition
Inattention and increased distractibility
Poor impulse control
Motor restlessness
Often under achieves in school, although has average to above-average intellect
Low self-esteem and problems with interpersonal relationships
Term
Manifestations of adhd: In children, at least 6 of the following (5 for adults):
Definition
Difficulty listening and understanding
Inability to express ideas
Difficulty differentiating words that look or sound alike
Difficulty remembering personal information or spelling
Difficulty copying forms, printing, writing
Confusing left and right
Difficulty concentrating and impatient
Term
the child with adhd Exhibits at least three signs or symptoms of inattention:
Definition
Easily distracted, needs calm atmosphere, fails to complete work, doesn’t appear to listen, difficulty concentrating unless one-on-one, needs information repeated
Term
the child with adhd Exhibits at least three signs or symptoms of impulsivity:
Definition
Disruptive with other children, talks out in class, extremely excitable, cannot wait turn, overly talkative, and requires a lot of supervision
Term
the child with adhd exhibits two signs or symptoms of hyperactivity
Definition
Climbs on furniture, fidgets, always “on the go,” cannot stay seated, does things in a loud and noisy way
Term
medical treatment for adhd involves dopaminergic agonists which include
Definition
Ritalin or Concerta (methylphenidate)
Focalin (dexmethylphenidate)
Dexedrine (dextroamphetamine)
Adderall (amphetamine/dextroamphetamine)
Strattera (atomoxetine)
Term
complementary and alternative therapy for adhd
Definition
Biofeedback
Yoga
Dietary interventions
Term
the nervous system is divided into two main parts
Definition
central nervous system, peipheral nervous system
Term
the CNS is made up of
Definition
the brain and spinal cord
Term
the peripheral nervous system which comprises all enrves of the distal parts of the body includign both
Definition
spinal and cranial nerves
Term
helps mainatin homeostasis for the body
Definition
autonomic nervous system
Term
stress triggers the _ to increase the secretion of epinephrine and norepinephrine
Definition
sympathetic nervous system
Term
mediates a rest respons
Definition
parasympathetic nervous system
Term
includes structural problems such as hydrocephalus
Definition
developmental and genetic disorders
Term
example of genetic disorder
Definition
huntington disease
Term
examples of disease states that cause inflammation of meningeal tissue and brain tissue, respectively
Definition
meningitis and encephalitis
Term
the primary degenerative disease of the brian is
Definition
alzheimer disease
Term
other degenerative disorders of the brain
Definition
MS, parkinson diseas, amyotrohpic lateral sclerosis, huntington disease
Term
four major components of a routine neurologic examination that provide valuable information regarding the overal integrity of the CNS
Definition
level of consciousness, pupillary evaluation, neuromuscular response, vital signs
Term
on the glasgo coma scale a normal alert person would score _, a person in a coma would score a _ or less
Definition
15, 7
Term
the primary function of the cranial nerve is to control
Definition
sensory, motor and autonmic activities of the head and neck
Term
to perfomr the _ have the patient stand with feet together and arms at his or her sides, instruct the patient to close his or her eyes and maintain that position
Definition
romberg test
Term
an invasive procedure that is used most often to detect infections and other disorders of the CNS, tumors and hydrocephalus
Definition
lumbar puncture
Term
for lumbar puncture the cannula is inserted into the subarachnoid space at the level of the
Definition
fourth or fifth lumbar vertebra
Term
entering at the fourth or fifth level for lumbar puncture allows the physician to avoid traumatizing the spinal cord which ends at the level of the
Definition
second lumbar verterbra
Term
normal CSF has the following characteristics
Definition
pressure 50-175 mm H20, ph 7,30-7.40, cleare, colorless appearance, fasting glucose 40 to 80 mg/dL, white blood cells 0-5 small lymphocytes/mm2
Term
a graphic representation of electrical activity in brain cells
Definition
electroencephalography
Term
studies the response of peripheral motor and sensory nerves to electrical stimuli, needle electrodes are placed on several points over a nerve and overa the muscles supplied by the nerve
Definition
electromyogrpahy
Term
provides images of the cerebral carotid and vertebral blood vessels
Definition
cerebral angiography
Term
cerebral angiography is the most definititive diagnostic test in the diagnosis of
Definition
cerebral aneurysm or congenital vasular disorders such as arteriovenous malformation
Term
risk of cerebral angiography
Definition
sever allergy to contrast media, embolus, hematoma, hemorrhage, renal toxicity, transient ischemic attack, infection and loss of consciousness
Term
obtained to visualize the spinal cord and vertebrae
Definition
myelogram
Term
the puncture for mylography is made in the lumbar area between
Definition
l3 and l4
Term
for a myelography and _ must be signed
Definition
informed consent
Term
before surgery, if the patient has cerebral edema _ may be ordered to help reduce cerebral swelling
Definition
corticosteroids
Term
the pt having a craniotomy is at risk for
Definition
ICP, CSF leak, meningitis and seizures
Term
as ICP increases the perfusion to brain tissue
Definition
decreases
Term
the minimum perfusion pressure necessary to ensure adequte cerebral functioning
Definition
70 mm Hg
Term
if perfusion pressure falls to _ ischemia occurs
Definition
40 mmHg
Term
a perfusion pressure of _ or less is incompatible with life
Definition
30 mm Hg
Term
hypothalamic impairment results in the loss of
Definition
temp control
Term
as ICP compresses the tissue around the hypothalamus it becomes _ and unable to regulate body tissue
Definition
ichemic
Term
cushings triad
Definition
hypertension, bradycarida, widening pulse pressure
Term
one of the mainstays of treatment for ICP
Definition
IV mannitol administration
Term
hyperosmolar diuretic that draws edema fluid from the tissue spaces into the bloodstream
Definition
mannitol
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