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Nucleic Acids and the RNA World
Freeman-Biological Science-Chapter 4
15
Biology
Undergraduate 1
09/22/2010

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Term

RNA

(ribonucleic acid)

Definition
a nucleic acid composed of ribonucleotides that usually is single stranded and functions as structural components of ribosomes (rRNA), transporters of amino acids (tRNA), and translators of the message of the DNA code (mRNA)
Term
nucleic acids
Definition

a macromolecule composed of nucleotide monomers

generally used by cells to store/ transmit hereditary info

includes ribonucleic acid and deoxyribonucleic acid

Term
nucleotide
Definition
a molecule consisting of a 5-carbon sugar (ribose or deoxyribose), a phosphate group, and one of several nitrogen-containing bases. DNA and RNA are polymers of nucleotides containing deoxyribose (deoxyribosenucleotides) and ribose (ribonucleotides), respectively. Equivalent to a nucleoside plus one phophate group.
Term
sugar
Definition
synonymous with carbohydrate, though usually used in an informal sense to refer to small carbohydrates (monosaccharides and disaccarides)
Term
purines
Definition
a class of small nitrogen-containing, double-ringed bases (guanine, adenine) found in nucleotides
Term
pyrimidines
Definition
a class of small, nitrogen-containing, single-ringed bases (cytosine, urasil, thymine) found in nucleotides
Term
phosphodiester linkage
Definition
Chemical linkage between adjacent nucleotide residues in DNA and RNA. Forms when the phosphate group of one nucleotide condenses with the hydroxyl group on the sugar of another nucleotide.
Term
phosphorylation
Definition
the addition of a phosphate group to a molecule
Term
antiparallel
Definition
describing the opposite orientation of the strands in a DNA double helix with one strand running in the 5' -> 3' direction and the other in the 3' -> 5' direction
Term

complementary base pairing

(Watson-Crick pairing)

Definition
the association between specific nitrogenous bases of nucleic acids stabilized by hydrogen bonding. Adenine pairs only with thymine (in DNA) or uracil (in RNA), and guanine pairs only with cytosine
Term
template strand
Definition

1. The strand of DNA that is transcribed by RNA polymerase to create RNA

2. An original strand of RNA used to make a complementary strand of RNA

Term
complementary strand
Definition
a newly synthesized strand of RNA or DNA that has a base sequence complementary to that of the template strand.
Term
hairpin
Definition

a secondary structure in RNA consisting of a stable loop formed by hydrogen bonding between purine and pyrimidine bases on the same strand.

Formed when a single strand folds back on itself to form a double helix "stem" and a single stranded "loop."

Term
monosaccharide
Definition

a small carbohydrate, such as glucose, that has the molecular formula (CH2O)n and can't be hydrolyzed to form any smaller carbohydrates

also called simple sugar

Term
disaccharide
Definition
a carbohydrate consisting of two monosaccharides (sugar residue) linked together
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