Term
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Definition
| analgesic and anti-inflammatory, antipyretic, irreversibly inhibits COX1, shows zero order kinetics |
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Term
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Definition
| analgesic, antipyretic, no cross reaction if there is NSAID hypersensitivity, analgesic ceiling and half life is comparable to aspirin |
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Term
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Definition
| analgesic and anti-inflammatory, antipyretic, effective for primary dysmenorrhea, higher analgesic ceiling and a longer half life to aspirin |
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Term
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Definition
| analgesic and anti-inflammatory, effective for primary dysmenorrhea, higher ceiling and longer half life compared to aspirin |
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Term
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Definition
| analgesic and anti-inflammatory, effective for primary dysmenorrhea, higher ceiling and shorter half life than aspririn |
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Term
|
Definition
| analgesic and anti-inflammatory, effective for primary dysmenorrhea, higher ceiling and longer half life compared to aspirin, a saliyclates |
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Term
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Definition
| anti-inflammatory only, a prodrug with an analgesic ceiling similar to aspirin and a longer half life than aspirin |
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Term
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Definition
| anti-inflammatory only, analgesic ceiling similar to aspirin |
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Term
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Definition
| analgesic only, analgesic ceiling comparable to morphine if given IV, but analgesic ceiling similar to ibuprofen if given orally |
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Term
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Definition
| anti-inflammatory only, COX2 inhibitor |
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Term
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Definition
| analgesic and anti-inflammatory, COX2 inhibitor, effective for primary dysmenorrhea |
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Term
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Definition
| short acting natural glucocorticoid, known as the stress hormone |
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Term
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Definition
| short acting synthetic glucocorticoid, can be given as a shot for joint problems |
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Term
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Definition
| potent synthetic mineralocorticoid with a longer half life (8-12 hrs) than cortisol |
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Term
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Definition
| short acting synthetic glucocorticoid, can be used as an immunosuppressant |
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Term
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Definition
| glucocorticoid half life between 12 to 36 hours |
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Term
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Definition
| potent synthetic glucocorticoid with a longer half life than cortisol |
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Term
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Definition
| blocks production of all mineralocorticoid, glucocorticoid and androgens, used as treatment for Cushing's of adrenal origin |
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Term
|
Definition
| blocks production of mineralocorticoids, used to determine the competency of adrenal axis |
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Term
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Definition
| inhibits dihydro-folate reductase, may cause homocysteinemia |
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Term
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Definition
| inhibits thymidylate synthase |
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Term
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Definition
| topoisomerase inhibitor, causes cardiotoxicity |
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Term
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Definition
| prodrug, a DNA alkylating drug |
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Term
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Definition
| DNA alkylating drug, may cause renal insufficiency |
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Term
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Definition
| mitotic spindle poison, inhibits microtubule formation, causes peripheral neuropathy |
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Term
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Definition
| mitotic spindle poison, enhances microtubule formation, causes peripheral neuropathy |
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Term
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Definition
| VEGF inhibitor, useful for macular degeneration, can cause hypertension |
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Term
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Definition
| EGF-R inhibitor, causes skin toxicities, diarrhea and vomiting |
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Term
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Definition
| HER-2 inhibitor, can cause cardiac side effects |
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Term
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Definition
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Term
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Definition
| EGFR kinase inhibitor, targets wild type |
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Term
|
Definition
| EGFR kinase inhibitor, targets t790m mutant |
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Term
|
Definition
| HER-2 kinase inhibitor, can cause skin toxicities, diarrhea and vomiting |
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Term
|
Definition
| abl inhibitor, used in leukemia |
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Term
|
Definition
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Term
|
Definition
| Proteasome inhibitor, gastrointestinal, sensorineural and neutropenic side effects, used for multiple myeloma |
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Term
|
Definition
| calcineurin inhibitor, binds to cyclophilin to inhibit calcineurin |
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Term
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Definition
| calcineurin inhibitor, binds to FKBP-12 to inhibit calcineurin |
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Term
|
Definition
| binds mTOR to inhibit T cell activation |
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Term
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Definition
| prodrug for mercapto-purine, inhibits the cell cycle |
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Term
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Definition
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Term
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Definition
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