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nongonococal urethritis
ONU med micro r-anderson
15
Microbiology
10/25/2011
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Term
causative agent
 Definition
chlamydia trachomatis
Term
etiology
 Definition
eubacterial pathogen
Gm- bacillus
obligate intracellular
Term
elementary body
 Definition
entry, and attachment
infectious form
Term
reticulate form
 Definition
replicates, non infection
Term
transmission
 Definition
horizontal: direct intimate contact
vertical: during birth
Term
entry
 Definition
std
Term
attachment
 Definition
elementary body adhesins bind to receptors on urogenital epithelium
Term
avoid defenses
 Definition
protected environment
elementary bodies engulfed by non-leukocytes
Term
damage
 Definition
direct: cell lysis
inlammation
Term
symptomatic females
 Definition
14 day incubation period
increased/abnormal discharge
strong, rather foul vaginal odor, painful urination,
Term
female complication
 Definition
3-5x risk of acquiring HIV
PID
Term
PID complication
 Definition
infertility, chronic pelvic pain, life-threatening-tubal pregnancy
Term
symptomatic males
 Definition
painful urination, burning/itching/discharge from/on penis
pain/swelling in testicles
Term
diagnosis
 Definition
specimen males: urine
specimen females: cervical mucous
PCR or DFA
Term
treatment
 Definition
tetracycline - doxycycline
or macrolide - azithromycin