Term
| ____ arthritis is also known as infectous arthritis. |
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Definition
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Term
| If we have a gonococcal infection it is always ______ |
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Definition
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Term
| IF we have a Gr+ cocci that is catalase +, what genus is it? |
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Definition
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Term
| How do you differentiate Staphylococcus auerus from epidermidis? |
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Definition
S. Aureus is coagulase +
S. Epidermidis is coagulase - |
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Term
| What does catalase convert? |
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Definition
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Term
| _____ hemolysis means no hemolysis. |
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Definition
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Term
| What are the virulence factors of Staphylococcus epidermidis? |
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Definition
Slime layer- allows attachment to prosthetics
Adhesins
Biofilms |
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Term
Eikenella corrodens:
Gr__
Oxidase __
(y/n) fermentative |
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Definition
Gr-
Oidase +
non fermentative |
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Term
What bacteria am I?
Human bite
pit agar
bleach like odor |
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Definition
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Term
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Definition
leading cause of septic arthritis for people under 4 years old.
Damage to respiratory mucosa facilitates invasion of bloodstream due to β-hemolysis. |
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Term
| What does β-hemolysis do? |
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Definition
| Lyses epithelial synovial cells and macrophages. |
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Term
Neisseria gonorrgoeae:
Gr__
Shape?
Oxidize glucose?
oxidize maltose?
Capsule?
how does it spread? |
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Definition
Neisseria gonorrgoeae:
Gr-
cocci
Glucose oxidizer
does not oxidize maltose
no capsule
disseminated gonococcal infection |
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Term
The genus Neisseria:
Gr__
Shape? |
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Definition
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Term
Neisseria meningitidis:
Gr__
Shape?
Oxidize glucose?
oxidize maltose?
Capsule? |
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Definition
Gr-
Cocci
Oxidizes glucose
Oxidizes maltose
has a capsule |
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Term
| In Neisseria gonorrhoeae there is an O side chain that is shorter than LPS what is this called? |
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Definition
| Lipooligosaccharide (LOS) |
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Term
| What medium do you grow N. gonorrhoeae on? |
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Definition
Chocolate or Thayer Martin (chocolate+antibiotics)
Would need Thayer martin for a sample from the asshole since there is so many other bacteria. For a knee you could use chocolate since the knee is sterile.
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Term
| What are the gonococcal virulence factors? |
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Definition
Adhesins (Opa and pili)
IgA1 protease
antigenic and phase variation Opa's, pili, LOS
Bind host sialic acid to their LOS
can make different surface proteins and turn things on and off. Sheds outer membrane.
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Term
| What are the 3 things you look at for a native joint infection? |
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Definition
| WBC count, gram stained smear, culture |
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Term
| What is the purpose of sonication? |
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Definition
| Used for prosthetic joint infections to disrupt the biofilm to release the organism and then identify it. |
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Term
| What is the reservoir of Ixodes scapularis? |
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Definition
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Term
| What is the vector for Ixodes scapularis? |
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Definition
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Term
| What is the vector for Borrelia burgforferi? |
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Definition
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Term
| What gives B. burgdorferi its mobility? |
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Definition
| bundles of axial filaments between plasma membrane and outer membrane. |
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Term
| What is the main symptom of early lyme disease and what bacteria causes it? |
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Definition
Erythema migrans (bull's eye rash)
B. burgdorferi |
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Term
| What is the main symptom of late lyme disease and what bacteria causes it? |
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Definition
lyme arthritis
B. burgdorferi |
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Term
| Describe how a direct immunologic method of diagnosis works |
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Definition
| look for presence of microbe antigens |
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Term
| Describe how a indirect immunologic method of diagnosis works |
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Definition
| look for host antibodies directed against the antigen. |
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Term
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Definition
| highest dilution (lowest concentration) of specimin that gives positive reaction in test. |
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Term
| Why is a culture not usually used for diagnosing lyme disease? |
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Definition
| Hard to grow and takes over a month. |
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