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Neuropathology Essentials
Lecture 3
17
Medical
Graduate
04/04/2011

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Cards

Term
areas of brain vulnerable to hypoxemia
Definition
CA-1 of hippocampus, Purkinje cells of cerebellum, cortical neurons
Term
area of brain vulnerable to carbon monoxide poisoning
Definition
globus pallidus
Term
areas of brain involved in PML (gray-white junctions)
Definition
subcortical white matter (oligodendroglia)
Term
areas of brain involved in MS
Definition
periventricular white matter
Term
Parkinson's inclusions
Definition
Lewy bodies
Term
Negri bodies; dx?
Definition
rabies
Term
Cowdry type A inclusions; dx?
Definition
HSV
Term
inclusions involved in aging
Definition
lipofuscin
Term
Alzheimer type II; definition?
Definition
astrocytic changes involving large vesicular nuclei and large glycogen droplets; seen in elevated plasma urea diseases and Wilson's
Term
Rosenthal fibers; definition? ddx?
Definition
irregular eosinophilic fibers containing 2 HSPs (ab-crystallin and hsp27); ddx: fibrillary gliosis, pilocytic astrocytoma, Alexander's disease
Term
corpora amylacea; definition? ddx?
Definition
round, lamellated bodies that are PAS+ and contain GAGs, located in subpia and astrocyte foot processes; ddx: Alexander's disease, aging
Term
5 microglia responses to injury
Definition
proliferation, nodules, rod cells, neuronophagia, phagocytosis
Term
slow bleed, initially lucid, slow decline, lesion in middle meningeal a.; dx?
Definition
epidural hematoma
Term
venous lesion, can last up to 2 wks; seen in alcoholics, elderly and shaken babies; dx?
Definition
subdural hematoma
Term
1. triethyl tin poisoning causes...
2. lead poisoning causes...
Definition
1. cytotoxic edema
2. vasogenic edema
Term
Kernahan's notch
Definition
compression of contralateral cerebral peduncle by herniating uncus causes false lateralizing sign; very rare
Term
[image]
Definition
PML
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