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Neurology: Motor
Master the Boards 2CK
19
Medical
Graduate
02/18/2013

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Cards

Term
What is the main give away of a Essential Tremor? x3

What is the Best initial treatment?
Definition
1. both rest and intention
2. BETTER with alcohol
3. Worse with Caffeine
Term
What is the treatment for mild disease of Parkinsonism? x3
Definition
AntiCholinergic medications-
--Benztropine and Trihexyphenidyl

Amantadine
Term
What is the treatment of Parinsonism for Severe disease? x5
Definition
Dopamine agonists: pramipexole and ropinirole (Pest inital therapy for severe parkensonism)

Levodopa/carbidopa

COMT inhibitors tolcapone, entacapone

MAOi- rasagiline, selegiline

Deep brain stimulation
Term
what are DA antagonists used in Parkensinism?

What drug class slows progression?
Definition
Pramipexole and ropinirole

MAOi
Term
What are the COMT inhibitors? x2

what do they do?
Definition
tolcapone, entacapone

extend duration of levo/carddopa by blocking metabolism of DA.
Term
What are the MAO inhibitors used in parkensonism?

When are they used?
Definition
Rasagiline, selegiline

used as a single agen or an adjunct to levodopa/carpidopa
Term
What is the treatment for spacicity? x3

what are the tree ass symptoms of Huntingtons
Definition
Baclofen, dantrolene
tizanadine-Alpha agonists

Movment, Memory, mood
Term
What is the treatment for RLS?

what is the impulsive swearing of tourette's called
Definition
DA agonist like: pramipexole

coprolalia
Term
What is the treatment for the --- in Huntingtons

Dyskinesia

Psychosis
Definition
Tetrabenazine

Haloperidol, quetiapine
Term
what is the most common SS and presentation of Multiple sclerosis


What is the cause of Ms?
Definition
MC is focal sensory symptomos with gait and balance,

blurry vision or visual disturbance

Ideopathic
Term
What is the BITest and MATest&R for MS?

What is found in lumbar puncture?
Definition
MRI is BIT and MAT

shows MSplaques appear white in white matter

LP show oligoclonal bands in 85%
Term
What is the Treatment for MS?

Acute?

to prevent Relaps?(first choice)
Definition
Acute: steroids

Pr: first choice is
1. Glatiramer (copolymer-1)
2. Beta- interferon

others including Natalizumab
Term
what MS medication can cause white matter hypo dense lesions with progressive neuro defects?

what is the diagnostic test for ALS
Definition
Natalizumab causes Progressive multifocal leukoencephilopathy

Electromyography
Term
What is the treatment for ALS? x3

name what the drugs do.
Definition
Riluzole-lowers glutamate
Baclofen- lowers spacicity

CPAP/BiPaP, ventilation, tracheostomy
Term
What are the ass S&S for Charcot-Marie-Tooth?

MATest?

what is the treatment
Definition
Clawed foot Children

electromyography

no tx
Term
How can you distinguish between Bells and a seizure?

What is the treatment
Definition
Cant wrinkle forehead- bells
Can wrinkle forehead- seizure

Prednisone
Term
What is the associated bug in Guillain Barre syndrome?

What is the most specific dx test?

What is the treatment
Definition
Campy. Jejuni

Nerveconduction/ electromyography

IVIG or plasmapheresis

not both at the same time
Term
What is the BITest for Myasthenia Gravis?

MATest

what Image studies should be done?
Definition
Acetylcholine receptor antibodies
if not present
anti MUSK antibodies

electromyography

get CT/MRI/CXR for thymoma
Term
What is the best initial treatment for Myasthenia gravis

then what?

if acute crisis
Definition
Neostigmine, pyridostigmine

Thymectomy if under 60
Prednisone if over 60

IVIG or plasmapheresis
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