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Neurological & Reproductive Alterations
Patho Exam 4
53
Pathology
Graduate
12/06/2013

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Cards

Term
Glasgow Coma Scale
Definition
MEW
Motor Response: 6-obeys commands 1-none
Eye opening: 4-Spontaneous 1-never
Words: 5-oriented 1-none
Term
Injury Assoc. w/ poor pupillary reflex
Definition
brain stem function CN II & III
Term
Injury Assoc. w/ abnormal eye movements
Definition
CN III, IV, & VI
Term
Injury Assoc. w/ poor oculocephalic reflex
Definition
brainstem (eyes move with head rather than staying focused when head moves)
Term
Injury Assoc. w/ poor oculovestibular reflex
Definition
brainstem (eyes move toward vestibular stimulation)
Term
Injury Assoc. w/ poor corneal reflex
Definition
CN III (eyes close when touched
Term
Abnormal posturing
Definition
decerebrate: brain stem damage from lesions on the cerebellum--> extensor reflex (worse damage)
decorticate: brain stem damage including the corticospinal tract--> flexor reflex
Term
Persistent Vegetative State vs. Brain death
Definition
no cognitive function, reflexes/basal functions in tact
vs.
irreversible, fatal, and total loss of brain function
Term
Damage Secondary to Traumatic Brain Injury (TBI)
Definition
Hypoxia/ischemia, increased ICP/edema, excitatory amino acid (neurotransmitter) injury
Term
Increased ICP
Definition
S&S: severe head/neck/backache, N/V, dizziness/altered vision
Tx: Meds (Glaucoma meds, diuretics, headache meds), and surgery depending on the cause
Complication: Hematoma: vessel burst
Term
Intracranial Hematoma
Definition
epidural: arterial burst, collection of blood outside of dura mater, pressure on the brain
subdural: venous burst in subarachnoid space
Tx: surgery
Term
Hydrocephalus
Definition
ventricular drainage is clogged--> CSF build-up--> pressure on brain--> multiple signs & symptoms dependent on age
Term
Three types of TBI
Definition
Concussion: momentary interruption of brain function
Contusion: bruising of brain surface
Axonal Injury: axonal damage in cerebrum, corpus callosum, and brain stem
Term
Ischemic Stroke
Definition
Thrombotic: arteriosclerosis--> thrombus--> cerebral ischemia--> CVA
Embolic: a-fib, valvular disease, endocarditis--> venous stasis--> low CO--> CVA
Term
Risks, Signs & Symptoms, and Treatment for Stroke
Definition
Risks: poor diet/exercise, family history/AfAm/male, age 55+
S&S: FAST
Tx: Ischemic: restore blood flow (aspirin, TPA, anti-clotting agents)
Hemorrhagic: reduced bleeding (surgery)
Term
Seizures
Definition
Patho: recurrent episodes of abnormal electrical discharges of the brain due to head injury, meningitis, tumors, etc.
Classifications: simple, complex, secondary
S&S: LOC, spasms & rigidity (tonic-clonic), loss of tone
Term
Meningitis
Definition
Patho: bacterial/viral/fungal infection of the CNS
S&S: Hi WBC, Hi Protein, positive culture, etc.
Tx: antibiotics, anticonvulsants, shunting in the case of hydrocephalus
Term
Spinal Cord Injury
Definition
Patho: trauma displaces spine, strains spinal cord
S&S: loss of function of body parts related to extent of damage
Tx: w/in 4 hours: immobilization and corticosteroids
Term
autonomic dys/hyperreflexia
Definition
loss of control of autonomic reflexes, doesn't happen when it should/happens more frequently than necessary
treat with stimulants or adrenergic blocking agents as the case may be
S&S: vasospasm
Term
Action of Androgens
Definition
Sexual development and secondary characteristics, protein anabolism, and stimulation of EPO
Term
Hypogonadism
Definition
Testosterone deficiency (normal 300-1000ng/dL); can be primary, secondary, or tertiary, each having different clinical manifestations including decreased fertility, fatigue, and muscular atrophy
Term
Hypo- vs. epispadius
Definition
congenital termination of the urethra on the ventral vs. dorsal surface of the penis, rather than the end
Term
Cryptoorchidism
Definition
P: Undescended testicles (normally descend 0-3 mo.s)
M: Infertility, malignancy/torsion, psychological effects
T: hormonal therapy, orchiopexy
Term
Hydrocele
Definition
P: accumulation of fluid between the tunica vaginalis and the testicle due to infection/lymph obstruction, tumor/radiation, or injury
M: pain, heaviness
Term
Hematocele
Definition
P: collection of blood in the testicles due to bleeding disorder, etc.
M: purpling/reddening
Term
Spermatocele
Definition
painless, sperm-containing cyst which forms in the epididymis
Term
Varocele
Definition
Varicosity in the testicular veins
Term
Testicular Torsion
Definition
P: testicle rotates--> spermatic cord twists--> ischemia in 8-18 year olds,
M: PAIN
Term
benign prostatic hyperplasia (BPH) R
Definition
Age, most common in men over 60
Term
BPH P
Definition
excess growth of epithelial and smooth muscle cells of prostate--> compression and occlusion of urethra
Term
BPH S&S
Definition
urinary frequency/urgency/hesitancy, dysuria, and nocturia
Term
BPH Tx
Definition
watchful waiting, invasive tx, or drug therapy
Term
erectile dysfunction
Definition
Risk: psychogenic (performance anxiety, depression, strain) & organic (diabetes, low T, drugs, etc)
Patho: persistant inability to achieve/sustain an erection
Tx: cyclic GMPs, & surgery
Term
male inflammatory disorders
Definition
balanoposthitis: inflammation of penis and foreskin--> ulceration/scarring; balanitis: inflammation of the penis
Epididymitis: duh
orchitis: inflammation of the testicles
Term
Prostate cancer
Definition
Risk: hi fat diet, ethnicity (AfAm, Asian), & family history
tx: chemo, radiation, surgery
Term
Amenorrhea
Definition
absence of menstruation
Term
Hypomenorrhea
Definition
scanty menstruation
Term
Oligomenorrhea
Definition
infrequent menstruation
Term
Polymenorrhea
Definition
frequent menstruation
Term
Menorrhagia
Definition
excessive menstruation
Term
Metrorrhagia
Definition
bleeding between periods
Term
Menometrorrhagia
Definition
heavy bleeding during and between periods
Term
Dysmenorrhea
Definition
painful/discomforted menstruation
Term
Endometriosis
Definition
functioning endometrial tissue in ectopic sites
presents as pain, and ectopic bleeding during menstruation
tx with contraceptives and surgery
Term
Cysto- vs. Rectocele vs. Uterine prolapse
Definition
the herniation of the bladder vs. rectum vs. uterus into the vagina
risks: abdominal pressure, aging, & menopause
Term
Leiomyomas (Fibroids)
Definition
P: benign tumors; types: submucosal (just beneath endometrial tissue, most problematic), intramural (embedded in myometrium), and subserosal (just beneath perimetrium)
M: Painful menses, excessive bleeding
Tx: pain management, contraceptives, or surgery (depending on severity)
Term
Menstrual Cycle
Definition
Follicular Phase: estrogen is produced by follicle (positive feed-back) until FSH & LH spike causing ovulation; endometrium has built to its full thickness at this time
Luteal phase: estrogen production drops post-ovulation, progesterone is produced by corpus luteum, after which it dissipates if the egg does not implant; the drop in progesterone causes menstrual flow
Term
Trichomoniasis
Definition
P: anaerobic bacteriotrophic bacterial, and sexually transmitted infection
S&S: positive microscopic exam; frothy, malodorous, green-yellow discharge; strawberry spots
Tx: antibiotics
Term
Chlamydia
Definition
P: sexually transmitted chlamydia trachomatis infection
S&S: most are asymptomatic
Tx: antibiotics
Term
complications from chlamydia
Definition
ocular disease in neonates (profilactic eye cream used on all neonates)
PID
Infertility
Term
Candidiasis
Definition
"yeast infection"
P: opportunistic infection <--antibiotic treatment
S&S: white, odorless discharge
Tx: antifungals
Term
HPV
Definition
Human Papilloma Viral, Sexually Transmitted Infection
S&S: serotypes 6 & 11--> genital warts
16 & 18--> linked to cervical cancer; otherwise generally asymptomatic
Tx: vaccine to prevent, pap smears to screen; wart removal
Term
Herpes
Definition
P: Herpes simplex viral, sexually transmitted disease
S&S: chancres
Tx: antivirals and good hygiene
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