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Neuroimaging
Neruoscience Exam 2
43
Other
Graduate
03/01/2011

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Cards

Term
X-ray grayscale
Definition
dense structures appear more white, air and water appear black
Term
pneumoencephalography
Definition

not performed in 1st world countries

 

ventricles are filled with air to make them easy to visualize on x-ray

Term
X-ray views for Neuro
Definition

posterioanterior

lateral

caldwell

townes

base

stenvers

rheese

waters

Term
Uses of X-ray in neuroimaging
Definition

Trauma: fractures, localization of foreign bodies, detection of pneumocephalus

Evaluation of masses: displacement of calcifications, observation of abnormal calcifications, erosion of bone

Evaluation of calvarial disease: localized lesions, metastasis (bone tumor)

Term
Drawbacks of X-ray
Definition

exposure to x-rays

poor visualization of soft tissues

two-dimensional representation of 3D object

Term
tomography
Definition

thin section radiograph produced by creating a thin focus plane - moving the x-ray tube and film cassette siultaneously in opp. directions.

Blurs out overlying shadows

Term
Uses for tomography
Definition

internal auditory canals

optic foramina

sella turcica

skull base

spine

Term
CT scan
Definition

used to visualize hard and soft tissues

it uses computers to reassemble the image into a series of thin 2D slices

colors are same as an X-ray

Term
When is CT prefered over and MRI?
Definition
when there is a head trauma patient, because the CT scan can be performed quickly
Term
Hounsfield Unit
Definition

quantitative scale used for measuring radiodensity

lower density substances appear darker

Term

Houndsfield Unit for Air:

Houndsfield Unit for Water:

Houndsfield Unit for Bone:

Definition

-1000

0

400+

Term
Radio-opaque material can be used:
Definition

with CT (because it uses x-rays) to reveal vasculature

reveals wehre the blood-brain-barrier is broken down

ie. a rapidly growing tumor may appear white bc of lack of BBB

an abcess will appear as a dark structure surrounded by a white ring

Term
Uses of CT scan:
Definition

Trauma: intra and extracerebral hematomas, cerebral edema or contusions, skull fractures

Localization of intracranial mass lesions: tumors, intracerebral hematomas

Identification of vascular lesions: AV malformations, aneurysms

Determining Ventricular Size: hydrocephalus, pseudotumor cerebri

Term
Cerebral Angiography
Definition

iodinated contrast material is used, X-rays are used to visualize the arteries filled with the contrast agent

 

a series of x-rays are rapidly shot so that the arterial, capillary, and venous phases of the brain vasculature can be visualized

Term
With cerebral angiography, x-ray images are often:
Definition
reversed so that arteries with contrast media appear black on light bony structures
Term
How can cerebral angiography be used for information about neural structures?
Definition
their known anatomical locations can be inferred via their anatomical relationship to the vasculature
Term
Why is cerebral angiography being replaced with magnetic resonance angiography (MRA)?
Definition

although MRA is far more expensive, MRA avoids the surgical risk involved in the catheterization used to inject the contrast media

also, some patients have adverse reactions to the contrast media

Term
Uses of cerebral angiography
Definition
aneurysm, tumor mapping, atherosclerosis, metabolic disease, pseudoaneurysms
Term
What are the negatives about cerebral angiography?
Definition

exposure to x-rays

surgical risk

adverse reaction to contrast medium

2D representation 3D object

Term
Myelography
Definition

performed to image the spinal cord and nerve roots

lumbar or lateral cervical puncture to subarachnoid space, iodinated agent is injected

images are recorded on x-ray film

Term
Uses of myelography:
Definition

determination of spinal cord lesion

evaluation of relationship between spinal canal and bony spine

diagnosis of herniated disk

Term
Magnetic Resonance Imaging
Definition

a powerful magnetic field and radiowaves are used to image tissue

atoms will align their anatomic nuclei with the field, magnetic resonance energy is released when the aligned nuclei are perturbed

Term
In a T1 weighted MR image, __ appears dark and ___ is white. The CNS white matter is __ gray matter.
Definition

bone and CSF

fat

lighter

Term
In a T2 weighted MR image, ____ is dark and ___ is white. Flowing blood appears ___. CNS white matter appears ___ than gray matter.
Definition

dense bone and air

CSF and fat

dark

darker

Term
The best way to tell if you have a T1 or T2 weighted image is to examine ___ or ___. If they are white, then the image is ____.
Definition

ventricles

globes of the eye

T2 weighted

Term
Typically ___ is used to locate and discribe pathology, while ____ is used to display the normal anatomy of white vs. gray matter.
Definition

T2 weighted image

T1 weighted image

Term
___ images are restricted to the axial plane, but ___ images can be viewed from any plane (axially, coronally, or sagitally).
Definition

CT

MRI

Term
Coronal MRI scans are viewed as though you are looking at the patient:
Definition
in the face, and the slices are from an anterior to a posterior plane
Term
Axial scans are viewed as though you are :
Definition

at the patients feet looking toward their head, while the patient lays on their back in the machiene

 

these scans show the cerebral hemispheres from ventral to dorsal

Term
In both coronal and axial views the patients side is ___ the observers side.
Definition

opposite

 

(the patients left side is to the observers right)

Term
MRI contrast material?
Definition

contrast material can be used

gadolinium can be used to enhance vasculature and show breakdown of the BBB around tumors or abscesses

Term
What devices are safe to use in an MRI?
Definition

joint prosthesis

aortic aneurysm clips

bowel staples

 

- all after 8 wks

Term
Medical devices which cannot be scanned in an MRI are:
Definition

many cerebral aneurysm clips

pacemakers

epicardial pacing wires

some cochlear implants

most endovascular shunts

Term

Color on X-ray:

1) air

2) CSF

3) fat

4) blood

5) brain

6) bone

Definition

1. black

2. grayscale

3. grayscale

4. grayscale

5. grayscale

6. white

Term

Color on CT:

1) air

2) CSF

3) fat

4) blood

5) brain

6) bone

Definition

1. black

2. black

3. black

4. lighter gray

5. darker gray

6. white

Term

Color on T1 MRI:

1) CSF

2) Fat

3) blood

4) brain

5) bone

Definition

1. dark gray/black

2. white

3. grayscale

4. white matter lighter

5. dark gray/black

Term

Color on T2 MRI:

1) air

2) CSF

3) fat

4) blood

5) brain

6) bone

Definition

1. dark gray/black

2. white

3. white

4. dark (flowing) / white (MRA)

5. gray matter lighter

6. dark gray/black

Term
Functional MRI (fMRI)
Definition

the most powerful magnets are used to examine areas of the CNS that are metabolically active during a particular assigned task

 

computer adjusted so that there is a difference between oxygenated and deoxygenated hemoglobin

Term
In a fMRI, the metabolically active region of the CNS will have:
Definition
increased  blood flow with more oxygen extracted from the hemoglobin
Term
Positron Emission Tomography (PET)
Definition

a positively charged electron is produced and incorporated into pharmaceuticals

 

the pharmaceuticals are injected intravenously and give off gamma rays as they decay

 

the gamma rays are detected with a scanner that portray the distribution of the radionuclide through the brain

Term
PET is most commonly used to display:
Definition

images of local metabolic rate for glucose throughout the brain

 

can also be used for evaluating cerebral blood flow, oxygen metabolism, and neurotransmitter receptor density

Term
PET is used to detect and diagnose:
Definition

 detect tumors and epileptic foci in the brain

 

dianose degenerative conditions (Alzheimers)

Term
Single Photon Emission Computed Tomography (SPECT)
Definition

similar to PET, but provides less detail, and the available nuclides are of less biological interest

 

it is however, less expensive and more widely available than PET

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