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Neurobiology 2
Exam 3
28
Biology
Undergraduate 2
03/23/2009

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Term
ganglion cell receptive field
Definition
increases with periphery

tile the retina
Term
specialization of primate fovea
Definition
cone-->midget bipolar-->midget ganglion
Term
photoreceptors
Definition
color-blind

wavelength and intensity are completely confounded
Term
parallel pathways
Definition
multiple, independent groups of neurons that extract distinct signals from the environment and convey these signals in parallel to the next stage in the nervous system

-rods vs cones
-On vs Off bipolar cells
-midget (parvocellular projecting) vs parasol (magnocellular projecting)
Term
ganglion cells that project to thalamus
Definition
-midget
parasol
color opponent cells
Term
thalamus
Definition
major route for afferents to neocortex (vision, hearing, touch, temp, pain, taste)
Term
layer IV of primary visual cortex
Definition
strong input from LGN
Term
central 2 degrees of visual field of fovea
Definition
25% of VI
Term
central 10 degrees of visual field of fovea
Definition
50% of V1
Term
Parvo LGN cells
Definition
project to layer IVa, IVc-B
Term
magno LGN cells
Definition
project to layer IVc-a
Term
every layer of cortex
Definition
connected with thalamus
Term
layer 5
Definition
projects to subcortical targets
Term
pyramidal cells
Definition
excitatory
Term
layer 4 (spiny stellate cells)
Definition
excitatory, act locally
Term
V5
Definition
MT cells tuned for direction of motion
Term
MT necessary for motion perception
Definition
lesion MT increases % correlation, impairing ability to detect motion
Term
MT cells sufficient to explain motion detection
Definition
individual cells are equally sensitive as the animal
Term
basic phototransduction cascade
Definition
1. activated rhodopsin

2. activated transducin (G-protein)

3. activated PDE

4. either cGMP or GMP

if 1. channel opens
if 2. channel closes
Term
activation of rhodopsin
Definition
light strikes, conformational change occurs and results in excited R*
Term
activation of transducin
Definition
R* reacts with transducin, catalyzes binding of GTP to G alpha subunit, activates G
Term
activation of PDE
Definition
two G*s bind to inhibitory gamma subunits of PDE to make E*
Term
amplification 2 in phototransduction cascade
Definition
E* catalyzes hydrolysis of cGMP, lowers cG concentration
Term
closing of CNG channels
Definition
lowered cG concentration, reduced influx of Na and Ca through channel
Term
difference between Rod and Cone
Definition
1. different opsins

2. different spatial densities depending on retinal location

(fovea dense with cones)
Term
base
Definition
narrow and stiff; higher freq
Term
apex
Definition
wide and floppy; lower freq
Term
amplification in middle ear
Definition
large tympanic membrane to small oval window
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