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Neuroanatomy
Dr. Masty 2010
144
Medical
Professional
03/31/2010

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Term
Neural Plate
Definition
Mass of cells, thickening of neural ectoderm
Term
Neural Groove
Definition
Folding of the neural plate
Term
Neural Folds
Definition
Dorsal projections of the neural fold
Term
Neural Tube
Definition
Neural folds fuse to form a cylinder
Term
Neural Crest Derivatives
Definition
Cells that pinch off when tube forms
Term
What are dorsal root ganglia also known as?
Definition
Spinal ganglia
Term
Ganglion
Definition
Collection of neuronal cell bodies outside the CNS
Term
Which nerves have sensory ganglia?
Definition
Cranial nerves
Term
Where are autonomic ganglia located?
Definition
Walls of the viscera
Term
What does the adrenal medulla contain & produce?
Definition
Contains specialized neural tissue
Produces neurosecretory products
Term
Vesicle
Definition
outpouching
Term
Primary vesicle stage of brain development
(3 parts)
Definition
Prosencephalon
Mesencephalon
Rhombencephalon
Term
What does the prosencephalon turn into?
Definition
Forebrain structures (splits into 2 parts)
Term
What does the mesencephalon give rise to?
Definition
Midbrain structures
Term
What does the rhombencephalon give rise to?
Definition
Hindbrain structures
Term
5 parts of the secondary vesicle stage
Definition
Telencephalon
Diencephalon
Mesencephalon
Metencephalon
Myelencephalon
Term
Which 2 secondary vesicle parts are derived from the prosencephalon?
Definition
Telencephalon
Diencephalon
Term
Which 2 secondary vesicle parts are derived from rhombencephalon?
Definition
Metencephalon
Myelencephalon
Term
What does the ventricular system form from?
Definition
Hollow part of the neural tube
Term
Parts of the ventricular system
Definition
Lateral ventricles (2)
Third ventricle
Fourth ventricle
Mesencephalic aquaduct
Term
Where are the lateral ventricles located?
Definition
Telencephalon
Term
What connects the left and right lateral ventricles (and the third ventricle)?
Definition
Interventricular foramen
Term
What flows through the ventricular system?
Definition
CSF
Term
What do the lateral ventricles look like?
Definition
Large, C-shaped
Term
Where is the third ventricle located?
Definition
Diencephalon
Term
What does the third ventricle look like?
Definition
Circular, like a donut
Term
what connects the third and fourth ventricles?
Definition
Mesencephalic aquaduct
Term
Where is the mesencephalic aquaduct located?
Definition
Mesencephalon
Term
Another name for the fourth ventricle
Definition
Rhomboid fossa
Term
Where is the fourth ventricle located?
Definition
Under the cerebellum
Term
What is another name for the lateral apertures?
Definition
Foramen of Luschka
Term
What is another name for the median aperture?
Definition
Foramen of Magendie
Term
Where do the lateral apertures open?
Definition
Into the subarachnoid space
Term
Where does the median aperture open?
Definition
Into the susterna magna
Term
What two parts of the brain is the fourth ventricle associated with?
Definition
Metencephalon
Myelencephalon
Term
How does closure of the neural tube proceed?
Definition
Starts in the middle then closure continues on each end
Term
What does failure to close the rostral neuropore lead to?
Definition
Anencephaly
Term
What does failure to close the caudal neuropore lead to?
Definition
Spina bifida
Term
What are brain flexures the result of?
Definition
Folding to fit in the skull
Term
3 brain flexures
Definition
Midbrain
Pontine
Cervical
Term
Where is the midbrain flexure?
Definition
On the cranial ventral surface
Term
Where is the pontine flexure?
Definition
dorsal surface
Term
Where is the cervical flexure?
Definition
caudal ventral surface
Term
The degree of cervical flexure folding depends on what?
Definition
The species and their lifestyle
Term
3 divisions of the nervous system
Definition
Central
Peripheral
Autonomic
Term
Features of the central nervous system
Definition
Brain
Spinal Cord
Term
Features of the Peripheral nervous system
Definition
Ganglia
Cell processes
Term
3 layers of the spinal cord
Definition
Marginal
Mantle
Ependymal
Term
Where is the marginal layer of the spinal cord?
Definition
Outermost
Term
Where is the mantle layer of the spinal cord?
Definition
Middle
Term
Where is the germinal layer of the spinal cord located?
Definition
Lining the canal and ventricular system
Term
What does the marginal layer of the spinal cord contain?
Definition
White matter: Axons & dendrites
Term
What does the mantle layer of the spinal cord contain?
Definition
Gray matter: cell bodies
Term
What does the germinal layer of the spinal cord contain?
Definition
Ependymal cells
Term
What is the sulcus limitans?
Definition
Dividing groove
Term
Where is the sulus limitans located?
Definition
Between the alar plate and the basal plate
Term
Where is the alar plate located?
Definition
Doral
Term
Where is the basal plate located?
Definition
Ventral
Term
What kind of information does the alar plate convey?
Definition
Sensory
Term
What kind of information does the basal plate convey?
Definition
Motor
Term
Where is gray matter located in the brain?
Definition
Cortical & Subcortical
(Surface & Nuclei)
Term
What is a nucleus?
Definition
Collection of cells imbedded in white matter
Term
What does white matter of the brain form?
Definition
Tracts, pathways, discrete structures
Term
Where are gray and white matter located in the spinal cord?
Definition
gray- under the surface
white- surface bundles
Term
What are the gray matter structures of the spinal cord?
Definition
Columns or horns
Term
What structures does spinal cord white matter form?
Definition
tracts and bundles
Term
What is a large bundle of white matter?
Definition
Funiculus
Term
What is a small bundle of white matter
Definition
Fasciculus
Term
Where is gray matter located in the peripheral system?
Definition
dorsal root ganglia (spinal ganglia)
autonomic ganglia
ganglia of sensory cranial nerves
Term
Where is white matter located in the peripheral nervous system?
Definition
nerve fiber bundles
Term
Where are the trapezoid body and caudal fourth ventricle located?
Definition
Myelencephalon
Term
What structure forms the rostral limit of the myelencephalon?
Definition
trapezoid body
Term
What structure indicates the caudal extent of the myelencephalon?
Definition
1st cervical nerve
Term
Where are the transverse fibers of the pons found?
Definition
On the ventral surface of the metencephalon
Term
Where is the cerebellum located?
Definition
On the dorsal surface of the metencephalon
Term
What are the three pairs of cerebellar peduncles?
Definition
Middle (aka lateral), caudal, and rostral
Term
How are the cerebellar peduncles named?
Definition
From where the fibers come from
Term
What is a cerebellar peduncle?
Definition
A stalk of white matter that attaches the cerebellum to the brain
Term
Where is the rostral half of the fourth ventricle located?
Definition
Metencephalon
Term
Where are the crus cerebri found?
Definition
On the ventral surface of the mesencephalon, in left and right bundles
Term
What two paired structures make up the corpora quadrigemina?
Definition
Rostral colliculus
Caudal colliculus
Term
In which adult brain section is the corpora quadrigemina found?
Definition
mesencephalon
Term
On a cross section of the mesencephalon, where are the tectum, tegmentum, and mesencephalic aquaduct found?
Definition
Tectum- dorsal
Tegmentum- ventral
Aquaduct- hole in middle
Term
What are the 5 subdivisions of the diencephalon?
Definition
Thalamus, Epithalamus, Metathalamus, Subthalamus, and Hypothalamus
Term
Which subdivision of the diencephalon cannot be grossly identified?
Definition
Subthalamus
Term
What is the optic chiasm?
Definition
Crossing of the optic nerves
Term
Where is the optic chiasm located?
Definition
On the ventral surface of the diencephalon
Term
What are the rostral and caudal limits of the diencephalon?
Definition
Rostral- optic chiasm
Caudal- mammillary body
Term
Where is the mammillary body located?
Definition
On the ventral surface of the diencephalon
Term
What is the path of the optic tract over the diencephalon?
Definition
Extends over the lateral surface, from ventral to dorsal
Term
What structures make up the metathalamus?
Definition
Lateral and medial geniculate bodies
Term
What is the site of terination of the optic tract?
Definition
Lateral geniculate body
Term
Where is the third ventricle found?
Definition
In the diencephalon
Term
Where is the epithalamus located?
Definition
On the dorsal midline of the diencephalon
Term
Which segment of the brain is made up of the cerebrum?
Definition
Telencephalon
Term
How is the cerebrum divided?
Definition
Into left and right hemispheres
Term
Where are the lateral ventricles located?
Definition
In the left (I) and right (II) cerebral hemispheres
Term
What is the general function of the ANS?
Definition
Coordinate the internal environment with external stimuli
Term
What are the divisions of the ANS?
Definition
Sympathetic and parasympathetic
Term
What happens to heart rate and GI motility under the influence of the sympathetic nervous system?
Definition
Heart rate goes up
GI motility goes down
Term
What happens to heart rate and GI motility under the influence of the parasympathetic nervous system?
Definition
Heart rate goes down
GI motility goes up
Term
What brain structure is the central control for the ANS?
Definition
hypothalamus
Term
Which portion of the hypothalamus regulates parasympathetic functions?
Definition
Rostral
Term
Which portion of the hypothalamus regulates sympathetic functions?
Definition
Caudal
Term
What are the target structures of the ANS?
Definition
Heart, smooth muscle, glands
Term
What are the target structures of the somatic system?
Definition
Skeletal muscle
Term
How many types of neurons make up the ANS?
Definition
2- excitation & inhibition
Term
How many types of neurons are in the somatic system?
Definition
one (excitation)
Term
What are the four classes of ANS ganglia?
Definition
Prevertebral, paravertebral, terminal, other
Term
What types of ganglia are found in the somatic system?
Definition
none
Term
What types of nerve fibers are found in the ANS?
Definition
Preganglionic & postganglionic
Term
How many nerve fibers are associated with a somatic system pathway?
Definition
1
Term
What neurotransmitter is secreted by both sympathetic and parasympathetic preganglionic fibers?
Definition
ACH
Term
What does a sympathetic postganglionic fiber secrete?
Definition
Norepinephrine
Term
What does a parasynpathetic postganglionic fiber secrete?
Definition
ACH
Term
Adrenergic refers to fibers of which system?
Definition
Sympathetic
Term
Cholinergic refers to fibers of which system?
Definition
Parasympathetic
Term
In a sympathetic pathway, which fiber is longer?
Definition
Postganglionic
Term
In a parasympathetic pathway, which fiber is longer
Definition
preganglionic
Term
Where are preganglionic cell bodies of the sympathetic NS found?
Definition
Lateral horn of thoracolumbar spinal cord
Term
Where are paravertebral ganglia located?
Definition
Next to vertebrae- either as the sympathetic chain or cervical ganglia
Term
What are the 4 cervical ganglia?
Definition
Cranial, middle caudal and cervicothoracic
Term
Where can you fins prevertebral ganglia?
Definition
Associated with blood vessels
Term
Which vessels have associated ganglia?
Definition
Celiac a.
Cranial mesenteric a.
Caudal mesenteric a.
Term
What are some "other" sympathetic ganglia?
Definition
Those associated with the aorta, kidney, adrenal gland
Term
What is the ramus communicans?
Definition
Communicating branch between the spinal nerve and the sympathetic chain
Term
Trace the pathway of sympathetic nerve fibers
Definition
Lateral horn out through ventral root and ramus communicans to synapse in a paravertebral ganglion, then out through a spinal nerve to target
Term
What does sudomotor refer to?
Definition
Sympathetic innervation of sweat glands
Term
What does pilomotor refer to?
Definition
sympathetic innervation to arrector pili muscles
Term
What does vasomotor refer to?
Definition
Sympathetic innervation of vascular smooth muscle
Term
Examples of sympathetic preganglionic named nerves
Definition
Major splanchnic, minor splanchnic, lumbar splanchnic
Term
Examples of postganglionic sympathetic named nerves
Definition
hypogastric, vertebral nerves
Term
Pathway of sympathetic innervation to the head
Definition
TL cord, ventral root, ramus communicans, sympathetic chain, CT ganglion, middle cervical ganglion, vagosympathetic trunk, cranial cervical ganglion, target
Term
What is the function of the parasympathetic nervous system?
Definition
Conserving and restoring the internal environment
Term
What is the function of the sympathetic nervous system?
Definition
Fight or flight response
Term
What portions of the spinal cord does the parasympathetic nervous system originate from?
Definition
craniosacral
Term
Which cranial nerves are associated with the parasympathetic nervous system?
Definition
C.N. III, VII, IX, X
Term
Which area of the sacral spinal cord do preganglion PNS fibers originate from?
Definition
lateral horn
Term
Where do postganglionic fibers of the PNS synapse?
Definition
Named ganglia or terminal ganglia in organ walls
Term
Where does the CN III component of the PNS originate and synapse?
Definition
Edinger Westphal nucleus
Ciliary ganglion
Term
Where do the CN VII components of the PNS originate and synapse?
Definition
rostral salivatory--> mandibular ganglion
lacrimal--> pterygopalatine ganglion
Term
Where does the CN IX component of the PNS originate and synapse?
Definition
caudal salivatory nucleus --> otic ganglion
Term
Where does the CN X component of the PNS originate and synapse?
Definition
dorsal vagal nucleus --> terminal ganglia in organ walls
Term
Where does the sacral component of the PNS originate and synapse?
Definition
PNS sacral neurons --> pelvic ganglion or terminal ganglia in organ walls
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