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Details

Neuro/Psych-Pharm
Stimulants and ADHD
7
Pharmacology
01/19/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

What is the mechanism of Methylphenidate

What are the adverse effects?

Definition

Block dopamine and some norepinephrine reuptake

Adverse

Anorexia

Insomnia

Cardiotoxic if underlying abnormality

Term
What are the amphetamines used to treat ADHD and what is their mechanism of action
Definition

Dextroamphetamine

Lisdexamfetamine

MOA: Enhances release and decreases reuptake of DA and NE

Term
What is the structure of lisamfetamine and how must it be administered, and its duration of action
Definition

lysine

PO only because degradation needed

8-12hrs

Term
What is the mechanism of Atomoxetine, how is it used in ADHD and its adverse side effects
Definition

Mech: Norepinephrine Reuptake inhibitor

2nd line if tolerance or resistance to Stimulants

Adverse: Anorexia,

Increase BP and Pulse Pressure

Hepatotoxicity

Term
What is the mechaism of clonidine or guanfacine, which ADHD symptoms is it more effective at treating, and what are the adverse effects?
Definition

Alpha-2 adrenergic agonists

Symptoms: Impulsivity and Hyperactivity(Off label)

Adverse: Orthostatic Hypotension, Sedation

Term
What is the mechanism of Bupropion?
Definition
Mechanism: Dopamine and norepinephrine reuptake inhibitor
Term
Drugs used to treat ADHD
Definition

Methylphenidate

Dexamphetamine

Atomoxetine

Bupropion

Clonidine/Guanfacine