Term
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Definition
MOA: Acute/abortive tx, selective 5HTR agonist
Use: closes shunt between arteriovenous anastamoses and restores flow to parenchyma
Tox: irritation @ injection site, tight chest, heavy head, coronary vasospasm |
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Term
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Definition
MOA: antiemetic, blocks 5HT3R (nAchR family, Lig gated, cations), only cation channel (others metabotropic)
USE: with antidepressants which incr ST->N and V |
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Term
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Definition
MOA: prophylactic tx, ST antagonist (blocks 5HT2), non spec effects on ST, adrenergic and Dopa neurons
USE: cluster HA
Tox: NVD, retroperitoneal fibrosis after prolonged use |
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Term
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Definition
MOA: ST antagonist
USE: migraines |
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Term
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Definition
MOA: prophylactic, ST antagonist
Use: Migraines |
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Term
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Definition
MOA: inhibits ST synthesis
Use: Migraines |
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Term
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Definition
MOA: partial 5HT2 agonist at some BV, nonsel 5HT antagonist at smooth m, partial agonist and antagonist effects a adrenergicR, constricts arteries and veins
Tox: N b/c direct action on CTZ, leg weakness, m. pain, numbness, vasospasm, contraindicated in preg and heart ds |
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Term
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Definition
MOA: prophylactic, tricyclic anticonv.
USE: antiepileptic drug |
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Term
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Definition
MOA: Prophylactic, Ca channel blocker
USE: migraines
Tox: orthostatic hypotension and constipation |
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Term
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Definition
MOA: Ca Channel blocker
Use: migraines
Tox: orthostatic hypotension and constipation |
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Term
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Definition
MOA: prophylactic tx, tricyclic antidepressant
Use: migraine |
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