Term
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Definition
- MOA: potentiate effect of GABA on GABAaR (bind to site distinct from whr GABA & allosterically potentiate effects of GABA), incr Cl flux
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Term
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Definition
- MOA: blocks alcohol metab, permits acetaldehyde to build up
- USE: alcohol abuse
- TOX: respiratory depression, arrythmias, CV collapse
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Term
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Definition
- MOA: analog of GABA, may be antagonist at NMDA R
- USE: alcohol abuse
- TOX:
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Term
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Definition
- MOA: blocks reward perception; opioid R antagonist-->decr DA release->etoh not as rewarding
- USE: alcohol abuse
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