Term
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Definition
alpha adrenergic agonist
MOA: a1 vasoconstriction-->incr peripheral res, syst and diast bp; incr in reflex vagal activity-->decr HR
USE: septic shock
Tox: Anxiety, tremor, headache, cerebral hemorrhage, card arrythm., decr BF to kidneys |
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Term
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Definition
Beta Agonist
MOA: B2 Bronchodilation, dilation of vessels, decr peripheral resistance, diastolic bp; B1 incr HR/contractile F/CO, systolic BP
USE: Resp. distress |
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Term
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Definition
Precursor of NE
MOA: Low-acts on D1R coupled to Gs->AC->cAMP->vasodil of renal vasc bed
Mod-acts on B1R->incr HR, contract F
High-a1R->vasoconstrict (Septic shock)
USE: renal dysfunction |
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Term
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Definition
Catecholamine like, B adrenergic agonist
MOA: like epi @ low dose, greater decr in periph. res and diastolic bp
USE: before for asthma, now stim heart in bradychardia or heart block |
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Term
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Definition
B adrenergic agonist, catecholamine like
MOA: like epi @ high dose, little effect on HR
USE: stim heart in CHF or MI |
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Term
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Definition
B2 selective agonist
MOA: lack of B1 activity decr incidence of cardiac side effects
Use: Asthma (inhal decr side effects)
Tox: anxiety, tremor, headache, arrythmias, seizures |
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Term
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Definition
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Term
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Definition
a1 adrenergic agonist
Use: mydriasis for retina exam, decongestant-acts on a1, vasocontrict, decr mucosa Vol, hemorrhoids
Tox: hemorrhagic stroke, contraindicated in hypertension, MAOI |
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Term
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Definition
a2 selective agonist, acts on central a2R in brain pressor centers
MOA: a2 in presynaptic R and neg feedback for nt
Use: hypertension |
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Term
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Definition
adrenergic agonist
MOA: alters vesicular storage of MOA, incr extravesicular MOA-->MOA pumped out by rev action
USE: CNS Stimulant, depress appetite, narcolepsy, ADD
Tox: euphoria, psychosis, dependencies, arrythmias-hypertension(NE release) |
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Term
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Definition
a and B adrenergic agonist
MOA: enhance NE release->CNS stim, Bronchodil, incr HR, CO, periph Res.
Use: lim. but in OTC herbals->prob for CV patients |
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