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Nervous Tissue
Nervous System
32
Biology
Undergraduate 2
03/15/2018

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Term
Types of neuroglia found in the CNS?
Definition
Astrocytes
Microglial cells
Ependymal cells
Oligodendrocytes
Term
Types of neuroglia found in the PNS?
Definition
Schwann cells
Satellite cells
Term
Type of neuroglia most abundant in the CNS?
Definition
Astrocyte
Term
Astrocytes
Definition
Connect neurons to nutrient supply and create a BBB.
Create a structural framework for CNS.
Guide neuron development.
Control interstitial environment.
Term
Microglial cell
Definition
Defensive (immune system) cells.
Transform into macrophage that phagocytize invading microorganisms.
Term
Ependymal Cells
Definition
Often ciliated.
Line central cavities of the brain and spinal cord.
Circulate cerebrospinal fluid surrounding the brain/spinal cord.
Term
Oligodendtrocytes
Definition
Serve as insulation. Form myelin sheaths around nerve fibers.
Term
Voltage
Definition
The measure of potential energy generated by separated electrical charges. Volts (V) or millivolts (mV).
Term
Leakage (non-gated channels)
Definition
Membrane channels that are always open. K+ and Na+ leaky channels found over entire cell.
Term
Chemically Gated Channels (ligand-gated channels)
Definition
Membrane channels that open when the appropriate chemical binds. Only on soma/dendrite.
Term
Voltage-gated Channels
Definition
Membrane channels that open and close in response to changes in the membrane potential.
Term
Mechanically Gated Channels
Definition
Membrane channels that open in response to physical deformation of the receptor. Only on soma/dendrite.
Term
Depoloarization
Definition
A decrease in membrane potential. The inside of the membrane becomes less negative (moves closer to zero) than the resting potential
Term
Hyperpolarization
Definition
An increase in membrane potential. The inside of the membrane becomes more negative (moves farther from zero) than the resting potential.
Term
Repolarization
Definition
Restores membrane to resting electrical conditions.
Term
Graded Potentials (dendrites and somas)
Definition
Short-lived localized changes in membrane potential. Can be either depolarization or hyperpolarizations.
Term
Graded Potentials
Definition
Magnitude varies directly with stimulus strength. Stronger the stimulus, the more voltage changes and the farther the current flows.
Term
Action Potential (axon)
Definition
Brief, long-distance signal within a neuron. Depolarization is followed by repolarization and often a short period of hyperpolarization.
Term
Action Potential
Definition
Activated by local graded potentials from the dendrites and somas that spread toward the axon.
Term
Excitatory Postsynaptic Potentials (EPSPs)
Definition
Type of Graded Potential that is a local depolarization of the postsynaptic membrane.
Term
Inhibitory Postsynaptic Potentials (IPSPs)
Definition
A type of Graded Potential where inhibitory neurotransmitters hyperpolarize the postsynaptic membrane by making it more permeable to K+ or Cl-.
Term
Postsynaptic Potentials
Definition
Converts chemical signals to electrical signals and mediate graded potentials that vary in strength based on the amount of neurotransmitter released and how long it remains in the area.
Term
"All-or-none" principle
Definition
An AP either happens or it doesn't. An AP is generated when enough Na+ enters the cell and reaches threshold. The AP is generated and propagated whether or not the stimulus continues, but if there are not enough Na+ ions to reach threshold, and AP will not occur.
Term
Temporal Summation
Definition
Occurs when one presynaptic neuron transmit impulses in rapid fire order and bursts of neurotransmitter are released in quick succession.
Term
Spatial Summation
Definition
Occurs when the postsynaptic neuron is stimulated simultaneously by a large number of terminals from many presynaptic neurons.
Term
Refractory Period
Definition
When a patch of neuron membrane is generating an AP and its voltage-gated sodium channels are open, the neuron cannot respond to another stimulus no matter how strong.
Term
Relative Refractory Period
Definition
Follows an absolute refractory period and occurs when an exceptionally strong stimulus reopen the Na+ channels that have already returned to their resting state and generate another AP.
Term
Propagation
Definition
How an AP moves along an axon's entire length to serve as the neuron's signaling device.
Term
Saltatory Conduction
Definition
In myelinated axons, APs are generated only in the myelin sheath gaps and jump from gap to gap. Myelin keeps current in the axons.
Term
Presynaptic Cell
Definition
Neuron conducting impulses toward the synapse.
Term
Postsynaptic Cell
Definition
Neuron transmitting the electrical signal away from the synapse.
Term
Synapse
Definition
Junction that mediates information transfer from one neuron to the next or an effector cell.
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