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Nervous System
CHAPTER 44 BSC1011
86
Biology
Undergraduate 3
03/31/2011

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Term
habituation
Definition
Prolonged exposure to a stimulus may cause cells to lose the ability to respond to it.
Term
cocaine
Definition
Drug that affects neurons in the brain's pleasure pathway (limbic system)
Term
nicotine
Definition
Drug that binds to a specific receptor in the postsynaptic neurons of the brain
Term
To what neurotransmitter does cocaine bind to?
Definition
dopamine
Term
How does the brain adjust to prolonged exposure to nicotine?
Definition
by making fewer nicotine receptors, and by altering the pattern of activation of nicotine receptors.
Term
What type of neurotransmitters are Glycine and GABA?
Definition
Inhibitory amino acid neurotransmitters
Term
IPSP?
Definition
Inhibitory postsynaptic potential; hyperpolarization produced by Inhibitory amino acid neurotransmitters such as Glyine and GABA.
Term
Glutamate?
Definition
Major Excitatory amino acid neurotransmitter in the vertebrate CNS.
Leads to excitatory postsynapti potential (EPSP) by causing Na+ influx
Term
Acetylcholine (ACh)
Definition
Neurotransmitter that crosses synapse between neuron and muscle fiber.
Causes muscle contraction.
Term
How does ACh neurotransmitter produce muscle contraction?
Definition
Binds to ACh receptors on muscle cell membrane and produces depolarization (EPSP) which stimulates muscle contraction.
Term
Acetylcholinesterase (AChe)
Definition
Neurotransmitter that degrades ACh, causing muscle relaxation.
Term
Biogenic amines
Definition
other types of neurotransmitters.
includes: epinephrine and norepinephrine, dopamine and serotonin
Term
Neuropeptides
Definition
Other types of neurotransmitters.
Includes: substance p, enkephalins and endorphins.
Term
Epinephrine and norepinephrine
Definition
Neurotransmitters that belong to the biogenic amines. Also known as adrenaline, causing the "fight or flight" response.
Term
Dopamine
Definition
Neurotransmitter that belongs to the biogenic amines. It is used in brain areas that control movement.
Term
Seronotin
Definition
Neurotransmitter that belongs to the Biogenic amines. It is involved in the regulation of sleep.
Term
Substane P
Definition
Neurotransmitter that belongs to the Neuropeptides. It is released from sensory neurons activated by pain.
Term
Enkephalins and endorphins
Definition
Neurotransmitters that belong to the Neuropeptides. These neurotransmitters lower pain perception.
Term
What are the two types of synapses?
Definition
Electrical synapses: rare in vertebrates, involve direct cytoplasmic connection between the two cells involved by gap junctions.

Chemical synapses.
Term
synaptic cleft
Definition
space that separates the two cells in a chemical synapse
Term
synapses
Definition
intercellular junctions
Term
presynaptic cell
Definition
neuron whose axon transmit action potentials to synapses
Term
postsynaptic cell
Definition
the cell receiving the signal on the other side of the synapse.
Term
Types of neurons
Definition
sensory(afferent) neurons, motor(efferent) neurons, interneurons
Term
sensory(afferent) neurons
Definition
carry info from sensory receptors to the CNS.
Term
motor (efferent) neurons
Definition
carry info from the CNS to the effectors.
Term
interneurons (association neurons)
Definition
located in the brain and spinal cord of vertebrates, aid in complex reflexes and associative functions such as learning and memory.
Term
What is the only major animal phylum without nerves?
Definition
sponges
Term
What animals have the simplest nervous system?
Definition
Cnidarians
Term
How is the nervous system of cnidarians arranged?
Definition
Neurons are linked together by a nerve net. It has no associative activity.
Term
Which are the simplest animals with associative activity?
Definition
flatworms (platyhelminthes)
Term
How is the nervous system of flatworms arranged?
Definition
Two nerve cords run down the body which permit complex muscle control
Term
What are the three basic divisions of all vertebrate brains?
Definition
hindbrain (rhombencephalon), midbrain (mesencephalon), forebrain (prosencephalon)
Term
Describe the hindbrain in fishes
Definition
It is the largest portion
Term
Describe the midbrain in fishes
Definition
it processes visual info
Term
Describe the forebrain in fishes
Definition
processes olfatory info
Term
which basic division became a dominant feature in the evolutionary ladder?
Definition
forebrain
Term
Elements of the forebrain
Definition
diencephalon, telencephalon("end brain")
Term
diencephalon
Definition
element of the forebrain, it includes the Thalamus and the Hypothalamus
Term
thalamus
Definition
element of the Diencephalon in the forebrain, it is the integration and relay center for visual, auditory and somatosensory info.
Term
hypothalamus
Definition
element of the Diencephalon in the forebrain, participates in basic drives and emotions, it controls the pituitary gland.
Term
telencephalon("end brain")
Definition
element of the forebrain, devoted to associative activity.
Term
gray matter
Definition
neurons cell bodies
Term
white matter
Definition
myelinated axons
Term
cerebrum
Definition
name given to the telencephalon in mammals.
Term
What does increased brain size reflects in mammals?
Definition
The relatively great enlargement of the cerebrum.
Term
What does increased brain size reflects in mammals?
Definition
The relatively great enlargement of the cerebrum.
Term
how is the cerebrum split.
Definition
into the right and left cerebral hemispheres.
Term
how are the right and left cerebral hemispheres connected?
Definition
by a tract called the corpus callosum
Term
How are each hemispheres divided?
Definition
Into 4 lobes: frontal, parietal, temporal and occipital lobes
Term
Each hemisphere receives sensory input from the opposite (contralateral) side. (true or false)
Definition
true
Term
cerebral cortex
Definition
is the outer layer of the cerebrum.
has a highly convoluted surface which triples the surface area of the human brain.
Contains about 10% of all neurons in brain (10 bill in humans)
Term
What are the regions of the cerebral cortex?
Definition
Primary motor cortex: movement and control
Primary somatosensory conrtex: sensory control
Association cortex: higher mental functions
Term
Basal ganglia
Definition
aggregates of neuron cell bodies forming islands of grey matter within cerebrum white matter
Term
pituitary gland
Definition
gland involved in instinctual and emotional responses
Term
Limbic system
Definition
emotional system, composed of the hypothalmus, cingulate gyrus, hippocampus and amygdala.
Term
hippocampus
Definition
part of the limbic system, has to do with consolidation (short-term and long-term memory)
Term
amydgala
Definition
part of the limbic system, almond shaped located deep within the temporal lobes, has roles in the processing and memory of emotional reactions
Term
cingulate gyrus
Definition
part of the limbic system, involved in emotion formation and processing, learning, memory, executive function of respiratory control.
Term
reticular formation
Definition
are the nuclei in pons and medulla which controls consciousness, alertness, sleep and waking states.
Term
Which structure of the brain is required for factual (declarative) memory formation?
Definition
the hippocampus
Term
Condition where memory and thought become dysfunctional?
Definition
Alzheimer disease
Term
Two causes of Alzheimer disease?
Definition
1- nerve cells are killed from the outside in by external protein B-amyloid.
2- Nerve cells are killed from the inside out by internal proteins tau (t)
Term
spinal cord
Definition
cable of neurons extending from the brain down through the backbone
Term
What encloses and protects the spinal cord?
Definition
The vertebral column and meninges (system of membranes)
Term
Functions of the spinal cord
Definition
relay messages between the body and the brain.
functions in reflexes.
Term
What type of reflex is the knee-jerk reflex?
Definition
monosynaptic reflex
Term
cerebral spinal fluid (CSF)
Definition
Considered the blood of the CNS, it is isolated from bloodstream (immune privileged), and it is located in the brain ventricles.
Term
What does the Peripheral Nervous system consists of?
Definition
nerves and ganglia
Term
nerves
Definition
bundles of axons bound by connective tissue.
Term
ganglias
Definition
aggregates of neuron cell bodies
Term
What is the function of the PNS?
Definition
to receive information from the environment and convey it to the CNS, which then carries responses to effectors such as muscle cells.
Term
What are the two systems in the PNS?
Definition
The somatic and the autonomic systems.
Term
What are the two systems in the PNS?
Definition
The somatic and the autonomic nervous systems.
Term
Somatic nervous system
Definition
Part of the PNS, somatic motor neurons stimulate the skeletan muscle to contract, in response to conscious command or reflex actions.
Term
Autonomic Nervous System
Definition
Part of the PNS, it controls involuntary functions through two divisions.
Term
What are the two divisions of the autonomic nervous system?
Definition
the sympathetic and the parasymphatetic divisions, plus the medulla oblongata.
Term
medulla oblongata
Definition
coordinates the autonomic nervous system.
Term
Similarities of sympathetic and parasympathetic divisions?
Definition
In both, the efferent motor pathway involves two neurons: preganglionic neuron and postganglionic neuron.
Term
preganglionic neuron
Definition
neuron of the sympathetic and parasympathetic division efferent motor pathway. It has its cell body in the CNS and sends an axon to an autonomic ganglion. It releases ACh at its synapses.
Term
postganglionic neuron
Definition
neuron of the symphatetic and parasympathetic divisions efferent motor pathways. It has its cell body in the autonomic ganglion and sends its axon to synapse with a smooth muscle, cardiac muscle or gland cell.
Releases ACh in the parasympathetic division.
Releases norepinephrine in the sympathetic division.
Term
Where do preganglionic neurons originate in the sympathetic division of the autonomic nervous system?
Definition
In the thoracic and lumbar regions of spinal cord
Term
Where do preganglionic neurons originate in the parasympathetic division of the autonomic nervous system?
Definition
In the brain and sacral regions of spinal cord.
Term
Describe axons in the sympathetic division of the autonomic nervous system.
Definition
Axons synapse in two parallel chains of ganglia right outside the spinal cord
Term
Describe axons in the parasympathetic division of the autonomic nervous system.
Definition
Axons terminate in ganglia near or even within internal organs.
Term
G proteins
Definition
Proteins that mediate responses to autonomic signals. Are activated by binding to ligand (ex: ACh).
An activated G protein proceeds to activate effector proteins.
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