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Nephrolithiasis
Clinical Medicine Test 3
15
Medical
Graduate
10/04/2010

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Cards

Term
What is the most common bacteria associated w/kidney stones?
Definition
-Klebsiella according to lecturer
-Proteus - notes
Term
What is found in most patients with Kidney stones
Definition
hematuria
Term
What size of stones will pass in <48hrs?
Definition
<5mm
Term
Best test for diagnosis of kidney stones?
Definition
Rapid CT
Term
What are the 4 interventional ways to remove kidney stones?
Definition
1) extracorporeal shock wave lithotripsy (ESWL)
2) percutaneous lithotripsy
3) retrograde basket retrieval
4) surgical intervention
Term
percutaneous nephrostolithotomy is indicated if?
Definition
1) extremely large (>2cm) or complex calculi
2) Cystine stones resistant to ESWL
3) Anatomic abnormalities
4) caliceal diverteicula
Term
lab sequence for diagnosing Calcium-containing stones:
Definition
1) Measure fasting urinary pH >6
2) Ammonia chloride acid loading test - if pH does not fall below 5.4 when bicarb falls below 20meq/L - distal renal tubular acidosis is present
Term
What are the two ways that distal renal tubular acidosis contributes to stone formation?
Definition
1) persistently high urine pH favors precipitation of calcium phosphate
2) low levels of citrate excreting inhibits stone formation
Term
triad found in lab for diagnosis of distal renal tubular acidosis
Definition
1) metabolic acidosis w/normal anion gap
2) alkaline urine pH
3) hypokalemia
Term
What is an important dietary risk factor for recurrent nephrolithiasis?
Definition
high protein intake
Term
what is the pharmacological treatment for calcium-containing stones?
Definition
1) Hydrochlorothizaide (HCTZ)
2) Amiloride
3) Neutral Na+ or K+ phosphate
4) Potassium citrate
Term
What is the treatment for hyperoxaluria?
Definition
1) calcium carbonate
2) cholestryamine
3) pyridoxine
Term
Treatment of Uric acid stones
Definition
1) sodium bicarb or potassium citrate
2) allopurinol - tx of choice for reducing uric acid secretion
Term
Large stones with staghorn appearance are consistent with what type of stones?
Definition
struvite stones
Term
What is an autsomal recessive disorder that has hexagonal crystals in urine?
Definition
Cystine Stones
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