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NBDE Flash! - Embryology
NBDE Flash! Part 1 Review Series. Home Page: http://www.flashcardmachine.com/p/nbdeflash
166
Dentistry
Professional
02/10/2012

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Term
What four things arise from surface ectoderm?
Definition
Adenohypophysis - Lens of eye - Epithelial linings - Epidermis
Term
What is the embryologic tissue origin of Microglia (ecto/meso/edo)?
Definition
Mesoderm
Term
What ear muscle does the 1st branchial arch form?
Definition
Tensor tympani
Term
Which embryonic tissue are branchial pouches derived from?
Definition
Endoderm
Term
What does the left 4th aortic arch give rise to?
Definition
Aortic arch
Term
What four structures make up the diaphragm?
Definition
- Septum transversum - Pleuroperitoneal folds - Body wall - Dorsal mesentery of esophagus
Term
Does the serous linings of body cavities arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
What effects does cocaine have on the fetus?
Definition
Abnormal fetal development and fetal addiction
Term
What is the male homologue to the greater vestibular glands (of Bartholin) in the female?
Definition
Bulbourethral glands (of Cowper)
Term
What are the 4th and 6th branchial arch derivatives innervated by?
Definition
CN X
Term
What is the female homologue to the ventral shaft of the penis in the male?
Definition
Labia minora
Term
The right common cardinal vein and right anterior cardinal vein give rise to what adult heart structure?
Definition
Superior vena cava
Term
What are the 1st branchial arch derivatives innervated by?
Definition
CN V2 and V3
Term
Which muscles (8) are derivatives of the 1st branchial arch?
Definition
- Temporalis - Masseter - Lateral pterygoid - Medial pterygoid - Mylohyoid - Anterior belly of digastric - Tensor tympani - Tensor veli palatini
Term
Which two embryonic tissues are branchial arches derived from?
Definition
Mesoderm and neural crests
Term
Which week of fetal development have the genitalia taken on male/female characteristics?
Definition
Week 10
Term
What part of the gut is the pancreas derived?
Definition
Foregut
Term
Does bone arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
Which embryonic tissue are branchial clefts derived from?
Definition
Ectoderm
Term
Where is the first place fetal erythropoiesis occurs and when does this take place?
Definition
Yolk sac (3-8 wk)
Term
What is oligohydramnios?
Definition
Less than 0.5 L of amniotic fluid
Term
Which branchial arch does Meckel's cartilage develop from?
Definition
1st arch
Term
What suppresses the development of the paramesonephric ducts in males?
Definition
Mullerian inhibiting substance (secreted by the testes)
Term
How does a cleft lip form?
Definition
Failure of fusion of the maxillary and medial nasal processes
Term
What does the primitive atria give rise to?
Definition
Trabeculated left and right atrium
Term
Does the pia arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
When do primary oocytes begin meiosis I?
Definition
During fetal life
Term
Does the gut tube epithelium arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
After arising from the floor of the primitive pharynx, where does the thryoid diverticulum go?
Definition
It descends down into the neck
Term
Which branchial arch forms the incus and malleus of the ear?
Definition
1st arch
Term
Do the chromaffin cells of the adrenal medulla arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
Which pharyngeal arch does Reichert's cartilage develop from?
Definition
2nd arch
Term
Is a secondary spermatocyte N or 2N?
Definition
2N
Term
Most oxygenated blood reaching the heart via IVC is diverted through the __ and pumped out the aorta to the head.
Definition
foramen ovale
Term
What does the foramen ovale give rise to?
Definition
Fossa ovalis
Term
What five things arise from neuroectoderm?
Definition
- Neurohypophysis - CNS neurons - Oligodendrocytes - Astrocytes - Pineal gland
Term
What are the five 2's associated with meckel's diverticulum?
Definition
- 2 inches long - 2 feet from the ileocecal valve - 2% of the population - Commonly presents in the first 2 years of life - May have 2 types of epithelia
Term
What is polyhydramnios?
Definition
Greater than 1.5-2 L of amniotic fluid
Term
What can be found in the cortex of the thymus?
Definition
It is dense with immature T cells
Term
Meiosis II is arrested in which phase until fertilization?
Definition
Metaphase (an egg MET a sperm)
Term
What is a urachal cyst or sinus a remnant of?
Definition
The allantois
Term
What is associated with an epispadias?
Definition
Exstrophy of the bladder
Term
How does a horseshoe kidney form?
Definition
Inferior poles of both kidneys fuse, as they ascend from the pelvis during development they get trapped under the inferior mesenteric artery
Term
What is the normal remnant of the thyroglossal duct?
Definition
Foramen cecum
Term
Although the diaphragm descends during development, it maintains innervation from ____?
Definition
C3-C5
Term
What is the flagellum (tail) derived from?
Definition
One of the centrioles
Term
What is the site of T-cell maturation?
Definition
Thymus
Term
What does the primitive ventricle give rise to?
Definition
Trabeculated parts of the left and right ventricle
Term
What does the thymus arise from?
Definition
Epithelium of the 3rd branchial pouch
Term
What are the cartilage derivatives (5) of the 4th and 6th branchial arches?
Definition
- Thyroid - Cricoid - Arytenoids - Corniculate - Cuneiform
Term
What does the 1st aortic arch give rise to?
Definition
Part of the maxillary artery
Term
What four things does Reichert's cartilage (from the 2nd arch) develop into?
Definition
- Stapes - Styloid process - Lesser horn of hyoid - Stylohyoid ligament
Term
What four things does the dorsal pancreatic bud become?
Definition
Body, Tail, Isthmus, and Accessory Pancreatic Duct
Term
Which is more common a hypospadias or epispadias?
Definition
Hypospadias
Term
What is a single umbilical artery associated with?
Definition
Congenital and chromosomal anomalies
Term
From what does the ligamentum teres hepatis arise?
Definition
Umbilical vein
Term
How does a bicornate uterus form?
Definition
Results from incomplete fusion of the paramesonephric ducts
Term
What does the 5th pharyngeal pouch develop into?
Definition
C cells of the thyroid
Term
Does the spleen arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
Is a primary spermatocyte 2N or 4N?
Definition
4N
Term
When does organogenesis occur in the fetus?
Definition
Weeks 3-8
Term
How long does full development of spermatogenesis take?
Definition
2 months
Term
What induces the ectoderm to form the neuroectoderm (neural plate)?
Definition
Notochord
Term
Does the thymus arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
What fetal landmark has occurred within week 3 of fertilization?
Definition
Gastrulation
Term
Which muscles (4) are derivatives of the 2nd branchial arch?
Definition
- Muscles of facial expression - Stapedius - Stylohyoid - Posterior belly of digastric
Term
What is the female homologue to the corpus spongiosum in the male?
Definition
Vestibular bulbs
Term
Do the urogenital structures arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
What is polyhydramnios associated with?
Definition
Esophageal/duodenal atresia and Anencephaly
Term
Is a spermatid haploid or diploid?
Definition
Haploid, N
Term
What four things does the mesonephric (wolffian) duct develop into?
Definition
- Seminal vesicles - Epididymis - Ejaculatory duct - Ductus deferens
Term
What is Potter's syndrome?
Definition
Bilateral renal agenesis, that results in ologohydramnios causing limb and facial deformities and pulmonary hypoplasia
Term
Is a speratogonium haploid or diploid?
Definition
Diploid, 2N
Term
After the first breath at birth, what causes closure of the ductus arteriosus?
Definition
An increase in oxygen
Term
What is a hypospadias?
Definition
Abnormal opening of penile urethra on inferior side of penis due to failure of urethral folds to close
Term
When does fetal erythropoiesis occur in the spleen?
Definition
Weeks 9-28
Term
What type of twins would have 2 amniotic sacs and 2 placentas?
Definition
Monozygotic or dizygotic twins
Term
What three things does the paramesonephric (mullerian) duct develop into?
Definition
- Fallopian tube - Uterus - Part of the vagina
Term
What does the spleen arise from?
Definition
Dorsal mesentery, but is supplied by the artery of the foregut
Term
What does the 4th pharyngeal pouch develop into?
Definition
Superior parathyroids
Term
What connects the thyroid diverticulum to the tongue?
Definition
The thyroglossal duct
Term
What type of twins would have 1 placenta, 2 amniotic sacs, and 1 chorion?
Definition
Monozygotic twins
Term
What two things occur during week 4 of fetal development?
Definition
Heart begins to beat and Upper and lower limb buds begin to form
Term
What embryologic defect is thoracic outlet syndrome caused by?
Definition
by having a cervical rib.
Term
How does a cleft palate form?
Definition
Failure of fusion of the lateral palatine processes, the nasal septum, and/or the median palatine process
Term
What does the right horn of the sinus venosus give rise to?
Definition
Smooth part of the right atrium
Term
Do the enterochromaffin cells arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
Do the lymphatics arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
Does the ANS arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
Which two branchial arches form the posterior 1/3 of the tongue?
Definition
3rd and 4th arches
Term
Does the pancreas arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
Which muscles are derivatives of the 6th branchial arch?
Definition
All intrinsic muscles of the larynx, except the cricothyroid
Term
What does the notochord give rise to?
Definition
Nucleus Pulposus
Term
What three structures does the 3rd pharyngeal pouch develop into?
Definition
- Thymus - Left inferior parathyroid - Right inferior parathyroid
Term
Is a secondary spermatocyte haploid or diploid?
Definition
Haploid, 2N
Term
What does the 6th aortic arch give rise to?
Definition
The proximal part of the pulmonary arteries and (on left only) ductus arteriosus
Term
What does the ligamentum venosum come from?
Definition
Ductus venosus
Term
What four things does Meckel's cartilage (from the 1st arch) develop into?
Definition
- Mandible - Malleus - Incus - Sphenomandibular ligament
Term
An abnormal opening of penile urethra on superior side of penis due to faulty positioning of the genital tubercle.
Definition
Epispadias
Term
Which branchial arch forms the anterior 2/3 of the tongue?
Definition
1st arch - Lateral Lingual Swellings
Term
What does aberrant development of the 3rd and 4th pouches cause?
Definition
DiGeorge's syndrome "CATCH 22"
Term
What is the food supply of sperm?
Definition
Fructose
Term
What embryonic structure are the smooth parts of the left and right ventricle derived from?
Definition
Bulbus cordis
Term
What embryonic structure does the coronary sinus come from?
Definition
Left horn of the sinus venosus
Term
What are the 2nd branchial arch derivatives innervated by?
Definition
CN VII
Term
When does fetal erythropoiesis occur in the bone marrow?
Definition
Week 28 and onward
Term
Which ear bone(s) does the 2nd branchial arch form?
Definition
Stapes
Term
Does the dorsal root ganglion arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
At what time in the course of development is the fetus most susceptible to teratogens?
Definition
Weeks 3-8
Term
What is the female homologue to the prostate gland in the male?
Definition
Urethral and paraurethral glands (of Skene)
Term
What fetal landmark has developed within week 2 of fertilization?
Definition
Bilaminar disk
Term
What does the truncus arteriosus give rise to?
Definition
The ascending aorta and pulmonary trunk
Term
What does the right 4th aortic arch give rise to?
Definition
Proximal part of the right subclavian artery
Term
What does the 2nd pharyngeal pouch develop into?
Definition
Epithelial lining of the palantine tonsils
Term
Do the melanocytes arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
Does the thyroid arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
What does the thyroid diverticulum arise from?
Definition
The floor of the primitive pharynx
Term
What is the acrosome of sperm derived from?
Definition
Golgi apparatus
Term
Meiosis I is arrested in which phase until ovulation?
Definition
Prophase
Term
When do primary oocytes complete meiosis I?
Definition
Just prior to ovulation
Term
How many arteries and veins does the umbilical cord contain?
Definition
- 2 umbilical arteries (carries deoxygenated blood away from fetus) - 1 umbilical vein (oxygenated blood to fetus)
Term
Do the neural crest cells arise from mesoderm, ectoderm, or endoderm?
Definition
Ectoderm
Term
What can be found in the medulla of the thymus?
Definition
It is pale with mature T cells, epithelial reticular cells, and Hassall's corpuscles
Term
After the first breath at birth, what causes the closure of the foramen ovale?
Definition
A decrease resistance in pulmonary vasculature causes increased left atrial pressure vs. right atrial pressure
Term
What does the first branchial cleft develop into?
Definition
The external auditory meatus
Term
The stapedius muscle of the ear is formed by which branchial arch?
Definition
2nd
Term
Which muscles (3) are derivatives of the 4th branchial arch?
Definition
- Most pharyngeal constrictors - Cricothyroid - Levator veli palatini
Term
Where does positive and negative selection occur in the thymus?
Definition
At the corticomedullary junction
Term
Does the adrenal cortex arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
What does the 5th aortic arch give rise to?
Definition
Nothing
Term
What teratogenic agent causes limb defects ('flipper' limbs)?
Definition
Thalidomide
Term
Which branchial arch are the greater horn of hyoid and the stylopharyngeus muscle derived from?
Definition
3rd branchial arch
Term
What does the 3rd aortic arch give rise to?
Definition
Common carotid artery and proximal part of the internal carotid artery
Term
What does the umbilical arteries give rise to?
Definition
Medial umbilical ligaments
Term
What fetal landmarks (2) have developed within week 3 of fertilization?
Definition
Primitive streak and neural plate begin to form
Term
Does the dura connective tissue arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
What will DiGeorge's syndrome lead to?
Definition
T cell deficiency and Hypocalcemia
Term
What does the ductus arteriosus give rise to?
Definition
Ligamentum arteriosum
Term
Does the liver arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
Does the parathyroid arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
Deoxygenated blood from the SVC is expelled into the pulmonary artery and __ __ to the lower body of the fetus.
Definition
Ductus Arteriosus
Term
Does blood arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
Do the lungs arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Endoderm
Term
What type of bone formation is spontaneous without preexisting cartilage?
Definition
Intramembranous
Term
Does the celiac ganglion arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
Does muscle arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
Do the odontoblasts arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
Do the cardiovascular structures arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Mesoderm
Term
Do the parafollicular (C) cells of the thyroid arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
What developmental contributions does the 5th branchial arch make?
Definition
None
Term
Which aortic arch does the stapedial artery and the hyoid artery come from?
Definition
2nd aortic arch
Term
What is Meckel's diverticulum?
Definition
Persistence of the vitelline duct or yolk sac
Term
What are the 3rd branchial arch derivatives innervated by?
Definition
CN IX
Term
What embryonic structure does the median umbilical ligament come from?
Definition
Allantois (urachus)
Term
What fetal landmark has occurred within week 1 of fertilization?
Definition
Implantation
Term
What does the ductus venosus shunt blood away from?
Definition
Liver
Term
What is the most common ectopic thyroid tissue site?
Definition
The tongue
Term
Do the Schwann cells arise from neural crest (ectoderm), mesoderm, or endoderm?
Definition
Neural Crest (Ectoderm)
Term
What is the most common congenital anomaly of the GI tract?
Definition
Meckel's diverticulum
Term
Where does spermatogenesis take place?
Definition
Seminferous tubules
Term
Is a primary spermatocyte haploid or diploid?
Definition
Diploid, 4N
Term
What do the 2nd - 4th branchial clefts form, which are obliterated by proliferation of the 2nd arch mesenchyme?
Definition
Temporary cervical sinuses
Term
What three things does the 1st pharyngeal pouch develop into?
Definition
- Middle ear cavity - Eustachian tube - Mastoid air cells
Term
Which branchial arches are the tongue derived from
Definition
1-3rd
Term
Where does the PDL, cementum, and the lamina dura of the alveolar bone arise from?
Definition
Dental Sac
Term
Mandiublar ossification
Definition
Intramembranous
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