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NAVLE Equine Internal Medicine
Equine Medicine
125
Veterinary Medicine
Professional
04/02/2009

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Term
Esophageal obstruction is aka ____. It is usually caused by what?
Definition
choke;
grain, hay, pelleted feeds, shavings, FB
Term
Clinical signs of choke:
Definition
frequent attemps to swallow, ptaslism, retching, feed/saliva draining, stretching of neck
Term
Common locations for choke:
Definition
cranial esophagus,
thoracic inlet,
heart base
Term
Treatment of choke:
Definition
sedation, mm relaxtion, NT tube/lavage, IV fluids, NSAIDs
Term
What is EGUS?
Definition
Equine gastric ulcer syndrome
Term
Where are gastric ulcers located in the adult horse and in foals?
Definition
Adults: Non-glandular (along margo plicatus)
Foals: glandular, duodenum
Term
How is EGUS treated?
Definition
Acid reducers (H2 antag, PPI, Antacids), Mucosal protectants (Sucralfate), Management (reduce stress, pasture/frequent feeding)
Term
____ is the most frequent cause of infectious colitis in the horse.
Definition
Salmonella
Term
How is Salmonella diagnosed in the horse?
Definition
Fecal culture/PCR
Term
____ is associated with acute colitis in the horse following AB treatment. It is a Gram ____.
Definition
Clostridium difficile
Gram + rod
Term
____causes peracute bloody diarrhea in foals and profuse dark and foul smelling diarrhea in adults. It is gram ___.
Definition
Clostridium perfringes
Exotoxin A and C
Gram +
Term
How is Clostridium perfringes diagnosed?
Definition
ELISA (for A/C)
Term
What is the etiology of Potomac Horse Fever?
Definition
Equine monocytic erhlichiosis, Neorickettsi risticci
Term
Where/when is Potomac horse fever seen?
Definition
NE and mid altantic in July-Sept
Term
How is Potomac horse fever diagnosed?
Definition
Fecal PCR/serology
Term
What is the etiology of canthardin toxicosis?
Definition
blister beetles in alfalfa hay in late summer/early fall
Term
What does cathanrdin do to the horse?
Definition
sloughing of all mucosa, diarrhea, hemorrhagic cystitis/nephritis, oral ulcer
Term
What would be some clinical signs of canthardin toxicosis?
Definition
abdominal pain, oral ulceration, rapid death, DECREASE ALB/Ca
Term
What does NSAID toxicity cause?
Definition
gastric/oral ulceration, renal papillary necrosis, RDC
Term
What is the order of NSAID toxicity in horses?
Definition
Bute>Flunixin>Ketoprofen
Term
What makes NSAID toxicity worse?
Definition
dehydration, hypovolemia
Term
What does Lawsonia intracellularis do?
Definition
proliferative enteropathy (also in horses); profound hyperplasia of the intestinal mucosa
Term
What age of horses are affected by Lawsonia?
Definition
foals 4-6 month
Term
HOW IS COLITIS TREATED?
Definition
Fluids, anti-diarrheas (biosponge, bismuth), anti-inflammatory/analgesia, AB controversial
Term
The use of AB in colitis is controversial, what are the different AB for them:
Definition
C. difficle: Metronidazole, PHF: Oxytetra, Lawsonia: Erythromycin/Rifampin
Term
What should not be felt on rectal exam:
Definition
NO small intestines
Term
Clinical signs of liver disease:
Definition
weight loss, CNS
Term
Lab signs of liver disease:
Definition
increased GGT, SDH, AST, ALP, Direct BIL, Bile acids
Term
Treatment of liver disease:
Definition
low protein diet, reduce ammonia producing bacteria in the gut (metronidazole, neomycin), anti-inflammatories, IV fluids
Term
What's Theiler's disease?
Definition
serum sickness; acute hepatic necrosis, occurs 4-10 wks after recieveing equine origin biologics (vx, antisera); poor prognosis
Term
What does the biopsy show in the case of Theiller's disease?
Definition
mid-zonal hepatic necrosis
Term
What is Tyzzler's disease?
Definition
Clostridium pilliformis (acute hepatic necorsis)
seen in newborn foals (7-42 days old),
Term
What are clinical signs of Tyzzler's disease?
Definition
severely ILL and icteric foal, increased bilirubin, hypoglycemia; grave prognosis
Term
Biopsy findings of Tyzzler's disease?
Definition
intracytoplasmic organisms seen with silver stain (in hepatocytes)
Term
Etiology of chronic active hepatitis in the horse?
Definition
idiopathic
Term
In what age group is cholithiasis seen in horses? What are the clinical signs?
Definition
6-15 yo, intermittent signs
Term
What gets hyperlipidemia/hepatic lipidosis?
Definition
minature horses/donkeys/ponies, obesity
Term
How do you diagnose hyperlipidemia?
Definition
TG >500 (the higher the TG, the poorer the prognosis)
Term
What are clinical signs of sinusitis?
Definition
unilateral nasal dc
Term
What are primary causes of sinusitis?
Definition
empyema (bacterial or viral URI)
Term
Secondary causes of sinusitis?
Definition
fungal granuloma, neoplasia, dental disease
Term
____are encapsulated angiomatous masses found in the URT, etiology is unknown.
Definition
ethmoid hematoma
Term
Clinical signs of ethmoid hematoma?
Definition
intermittent unilateral epistaxis in horses > 6 yo
Term
How are ethmoid hematomas dx?
Definition
endoscope: 50% are bilateral so SCOPE BOTH SIDES
Term
Tx of ethmoid hematomas?
Definition
4% formalin injections, sx (lots of blood), 50% reoccur
Term
What is the cause of strangles?
Definition
Streptococcus equi equi, highly contagious (<5 yo)
Term
How do you diagnose Strangles?
Definition
Culture/PCR of guttural pouch lavage or nasopharyngeal swab or lavage
Term
What is the treatment of strangles?
Definition
Isolation, AB (if complicated case only-Penicillin), LN drainage/compress, anti-inflammatories
Term
Sequale of strangles:
Definition
chondroid formation, tracheotomy, bastard strangles, purpera hemorrhagica
Term
Signs of purpera hemorrhagica?
Definition
aspectic vasculitis: immune complexes(IgA + M protein)
Signs are delayed: pitting edema in four legs and petichae
Term
Treatment for purpera hemorrhagica?
Definition
Penicillin, dex, anti-inflammatories
Term
What AB should you use to treat pneumonia?
Definition
Gram +: Pen, Ceftiofur
Gram -: Gentamycin, Enrofloxacin
Anaerobes: Pen, Metronidazole
Term
What does Rhodococcus equi cause?
Definition
PNEUMONIA IN FOALS (1-6m), chronic pyogranulamatous pneumonia
Term
Treatment for Rhodococcus equi?
Definition
AB (min 8-10 weeks): Macrolide (erythromycin, clarithro, azithro) + Rifampin, Strict exercise rest, if severe oxygen, bronchodilators, fluids
Term
What is the etiology of pleuropneumonia?
Definition
most arise as an extension of pneumonia or lung abscess...Streptococcus
Term
Clinical signs of pleuropneumonia?
Definition
guarded cough, painful/stilted gait, nasal dc
Term
How does pleuropneumonia ASCULT?
Definition
ABSENT LUNG SOUNDS VENTRALLY, RADIATING HEART SOUNDS DORSALLY
Term
Treatment for pleuropneumonia?
Definition
broad spec AB, remove excess pleural fluid, anti-inflammatories, analgesics, IV fluids
Term
What are the causes of Viral pneumonia in horses?
Definition
EHV 1/4 (4 also causes abortion and CNS), INFLUENZA(most common, highly contagious), Adenovirus
Term
What are some other names for COPD of horses?
Definition
Heaves, recurrent airway obstruction
Term
What are some etiologies of COPD?
Definition
hypersenstive to dust, molds, forage mites, aerosolized endotoxin
Term
What are clinical signs of COPD?
Definition
chronic cough, mucopurulent nasal discharge, increase RR/effort, nostril flare, exercise intolerance, heave line, NO FEVER
Term
What is the treatment of COPD in horses?
Definition
bronchodilator, reduce pulmonary inflammation (steriods), remove offending agent (stall), reduce pulmonary irritants (soak hay, pelleted feeds)
Term
What is the most common endocrine disease in horses that is a progressive chronic disease?
Definition
equine cushings syndrome
Term
What causes equine cushings?
Definition
pars intermedia dysfunction
Term
What are clinical signs of equine cushings?
Definition
HIRSITISM, muscle wasting, PU/PD/polyphagia, decrease response to pain
Term
How is equine cushing's diagnosed?
Definition
DEX SUPPRESSION**, plasma ACTH and DST (be careful interpreting in Sept)
Term
How is equine cushings treated?
Definition
PERGOLIDE
Term
Equine metabolic syndrome is aka:
Definition
peripheral cushing's syndrome, equine syndrome X
Term
Equine metabolic syndrome is characterized by:
Definition
obesity, insulin resistance, risk of laminitis, hypertension
Term
How is equine metabolic syndrome diagnosed?
Definition
CS, resting insulin/glucose (high, high insulin with increase to normal glucose)
Term
Treatment of equine metabolic syndrome?
Definition
low carb diet (no grain), exercise
Term
Causes of ARF in horses?
Definition
Aminoglycosides, NSAIDS, Cestrum diurnam, Lepto
Term
Clinical signs of ARF in horses?
Definition
depression, anorexia, PU/anuria, signs of primary dz
Term
What are causes of CRF in horses?
Definition
Glomerulonephritis, chronic intersitial nephritis, pyelonephritis, amyloidosis
Term
Signs of CRF in horses?
Definition
weight loss, PU, anorexia, ventral edema (PLN)
Term
The cerebral cortex is in control of:
Definition
behavior and metal status
Term
The brainstem contains:
Definition
CN
Term
The cerebellum is in control of?
Definition
coordiating movements
Term
The spinal cord is responsible for:
Definition
gait, posture, reflexes
Term
What causes Horner's syndrome?
Definition
damage to SNS to head caused by: perivascular injections, jugular trauma, GUTTURAL POUCH MYCOSIS, trauma to basisphenoid, cervical abscess/trauma, periorbital mass, esophageal rupture
Term
What are clinical signs of Horner's syndrome?
Definition
ptosis, miosis, endopthalmos, protrusion of nicitating membrane, sweating
Term
What are causes of viral encephalomyelitis?
Definition
Alpha: EEE, WEE, VEE; Flavi: WNV
Term
Can horses transmit viral encephalitis to humans?
Definition
Only VEE because horses develop a high viremia
Term
What are clinical signs of VEE, WEE, EEE?
Definition
Early: fever, anorexia, stiffness
Later: hyperestesia, aggression, continious chewing, frantic bx
Advanced: head pressing, circling, compulsive walking
Term
How is viral encephalitis transmitted? Main host?
Definition
Carried by birds, main host: mosquitoes
Term
What is the clinical course of rabies in horses?
Definition
< 10 days, FATAL
Term
What causes tetanus?
Definition
Clostridium tetani; HIGH mortality
Term
What causes EPM?
Definition
Sarcocystis neurona, carried by birds/oppossums
Term
What kind of lesions does EPM cause?
Definition
focal, multifocal, or diffuse, asymmetric, nonsuppurative inflammatory lesions
Term
How is EPM diagnosed?
Definition
Western blot ELISA (80% of healthy horses have titers) use with CS
Term
Treatment of EPM:
Definition
PONAZURIL, TMS + PYRIMETHAMINE, NITAZOXANIDE
Term
What are metabolic causes of CNS signs?
Definition
hepatic encephalitis
Term
What are toxic causes of CNS disease in horses?
Definition
leukoencephalomalacia, nigropalidal encephalomalacia, Pb posioning
Term
What are degenerative causes of CNS signs?
Definition
EDM, CVM
Term
What is the typical signalment of CVM?
Definition
TB 6m-3yrs, rapidly growing animals
Term
What are clinical signs of CVM?
Definition
ataxia/spasticity/weakness in all 4 but > in rear
Term
Recurrent equine rabdomyolysis aka:
Definition
Monday Morning disease
Term
What is the etiology of RER?
Definition
racing TB, 3-4 yo filly, >10# grain (carb)/day
Term
What are clinical signs of RER?
Definition
mild-severe cramping of hindquarters, pain, myoglobinuria
Term
How is RER diagnosed?
Definition
caffine or halothane contracture test
Term
Treatment of RER?
Definition
IV fluids, muscle relaxants, sedation, analgesia, minimize stress, reduced CHO diet (increase calories from fat), DANTROLENE
Term
What is the typical signalment of HyPP?
Definition
(Hyperkalemic periodic paralysis); QH, Paint, Appaloosa--Impressive gene
Term
Hypp is an autosomal ___ trait, a point mutation located on___________.
Definition
dominant,
skeletal mm Na channels
Term
Clinical signs of Hypp?
Definition
mm faciculations, myotonia, yawning, prolapsed 3rd eyelid, dog-sit stance
Term
Dx of hypp?
Definition
genetic testing: mane, hair
K+, >5 during episodes
Term
Tx of Hypp?
Definition
Immediate: Dextrose, Ca gluconate slow IV, Na bicarb
Longterm: low K diets (no alfalfa or molasses), small frequent meals, avoid stalling, min stress
ACETAZOLAMIDE (K losing diuretic)
Term
What is PSSM? Who gets it?
Definition
polysaccharide storage myopathy
QH, paint, appaloosa
Term
Clincal signs of PSSM?
Definition
sore muscles, especially after 20 minutes of exercise
Term
Etiology of PSSM?
Definition
point mutation of glycogen synthase enzyme-->accumulation of abnormal polysaccharide in skeletal m-->higher glycogen content
Term
How is PSSM diagnosed?
Definition
Bx: abnormal polysaccharide
genetic test: hair
Term
Treatment of PSSM?
Definition
regular exercise, diet (low glycemic index, increase calories from fat)
Term
Most common heart defect?
Definition
VSD
Term
Most common arythmia?
Definition
AV block
Term
Clinical signs of atrial fibrillation?
Definition
history of exercise intolerance, epistaxis post exercise, common and NOT always symptomatic
Term
Treatment of AF?
Definition
Quinadine, if high HR use Digoxin
Term
What is the wolf tooth?
Definition
upper PM1
Term
What AB shouldn't be used in horses?
Definition
clindamycin, lincomycin, macrolides (careful)
Term
Treating navicular disease?
Definition
egg bar shoe, want to raise the heel, PDN nerve block
Term
Treatment of laminitis?
Definition
heart bar shoe, NO corticosteriods
Term
Number 1 cause of anestrus during breeding in the mare?
Definition
persistant CL
Term
How do you treat a persistant CL?
Definition
PGF2alpha (Luteolyse) or Fluprostenol (Equimate)
Term
Most common cause of non-infectious abortion in the mare?
Definition
twins, double ovulation
Term
90% of lameness are located in:
Definition
the hoof
Term
Name the foot blocks:
Definition
heel block (palmar digital nerve block)-navicular dz
pastern block (foot block, abaxial sesamoid nerve block)-acute laminitis
fetlock block (low 4 pt, low palmar)
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