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N2O
Nitrous Oxide
40
Medical
Graduate
03/27/2009

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Cards

Term
N2O is a _____ gas with a ____ odor
Definition
Colorless, sweet
Term
Critical temp of N2O
Definition
36.5 C
Term
At 36.7 C, it takes ____ ATMs to compress N2O into a liquid
Definition
74 ATM
Term
N2O is in the ____ phase in the body
Definition
gas
Term
At 20 C, it takes _____ ATM to compress N2O into a liquid; therefore, the pressure guage will read _____ ATM or _____ psi.
Definition
51, 51, 745
Term
T/F your pressure gauge will not change even if you have only 1 mL N2O in the cylinder.
Definition
T
Term
N2O is/is not flammable and is/is not stable in soda lime.
Definition
is not, is
Term
N2O is a potent ______ but a weak ______
Definition
analgesic, anesthetic
Term
blood/gas partition coefficient for N2O
Definition
0.47
Term
________ leads to diffusion hypoxia with N2O.
Definition
Diffusion anoxia
Term
Diffusion anoxia is caused by 2 things: ______ of O2 and _______ of CO2 that results in an increased/decreased respiratory drive.
Definition
displacement, dilution, decreased
Term
Greatest effect of diffusion anoxia occurs within the first ___ to ___ mins, so deliver 100% O2 during this time, especially with ______ disease and when resp depression is expected post op (heavy opioids).
Definition
5-10, lung
Term
N2O will increase the pressure in an occluded ______ ear, occluded _____ and ______ that contain air.
Definition
middle, sinuses, cerebral ventricles
Term
N2O increases the _____ in cavities with compliant walls
Definition
compliant
Term
How long does it take to expand an air embolus with N2O?
Definition
Seconds, per Miller
Term
The magnitude of the pressure or volume increase with N2O depends on the _____ of N2O, _____ to the cavity, and the _______ of the anesthetic.
Definition
partial pressure (concentration), blood flow, duration.
Term
Is it appropriate to give N2O in a lap chole case?
Definition
No, it has the potential to over-expand the abd.
Term
At 10 mins, N2O will _____ the size of a pneumo. At 30 mins, it will _____ the size and at 45 mins, it will ____ the size, when given at 75% concentration.
Definition
double, triple, quadruple
Term
If the neurosurgeon is okay with you using N2O during a sitting posterior fossa craniotomy, turn up the doppler very high, and everyone in the room will listen for a _________.
Definition
mill wheel murmur.
Term
What is the gold standard to check for a saggital sinus air embolus?
Definition
T-echo
Term
What 2 diagnostic tools do we use to assess for an air embolus in a craniotomy before physiological changes are present?
Definition
T-echo and Doppler
Term
What 2 diagnostic tools do we have that assesses for an air embolus with a crani that will be present after modest physiological changes?
Definition
PAP, ET-CO2
Term
What 2 diagnostic tools do we have that assesses for an air embolus with a crani that will be present after clinically apparent physiological changes?
Definition
CO, CVP
Term
What 3 diagnostic tools do we have that assesses for an air embolus with a crani that will be present only after CV collapse?
Definition
BP, ECG, Stetho
Term
On a sitting crani, you MUST monitor these two end-tidal parameters.
Definition
ET-CO2, ET-N2
Term
WIth an air embolus, the ET-CO2 will increase/decrease. End-tidal N2 will increase/decrease.
Definition
decrease, increase
Term
N2O at 75% could ____ or _____ ETT cuff size, so check cuff pressures often.
Definition
double, triple
Term
If you had a pt with a pneumoencephalography, how long must the pt stay away from N2O?
Definition
7 days
Term
Post-op hearing loss caused by N2O is from expansion of ______ ear, and resolves within _____ to ____ days.
Definition
middle, a few hours (by the time they leave the PACU) to 2 days
Term
Tympanic membranes can rupture at ___ to ___ cmH2O. This increase in pressure can cause serious _____ and post-op _____.
Definition
20-30 cmH2O, otitis, N/V
Term
Is it appropriate to use N2O on COPDers?
Definition
No, because N2O can rupture their blebs.
Term
N2O will increase/decrease ICP?
Definition
increase it because it increases CMRO2 and CBF; coupled.
Term
If a pt develops increased ICP from N2O, will hyperventilating them help to reduce the ICP?
Definition
Yes. N2O does not block the hyperventilatory vasoconstriction response.
Term
The effects of N2O on the CNS can vary from pt to pt. Describe one characteristic.
Definition
The physical status of the pt.
Term
With N2O, CMRO2 and CBF are coupled/uncoupled?
Definition
coupled
Term
N2O + _____ or + _____ or + _____ will also decrease the ICP because these are cerebral vasoconstrictive agents.
Definition
Propofol, BZDs, Barbs (Note: Not opioids). This is true ONLY if the pt does not have a compromized compliance.
Term
N2O and what other INH agents increase CMRO2?
Definition
None. N2O is the only one that increased CMRO2.
Term
The CV pattern of N2O is inconsistent because_____
Definition
it's usually given with a host of other agents that also affect the CV system, such as opioids, volitile agents and anesthetic adjuncts.
Term
In general, N2O increases/decreases HR in healthy volunteers, in a hyperbaric chamber or with INH agents are added?
Definition
Increases HR
Term
N2O + volitile anesthetic = ______ or _____ in HR
Definition
no effect, increase
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