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Myocardial Isch, Inj & Infarct
Ischemia, injury and infarct
56
Medical
Graduate
03/29/2009

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Cards

Term
Ischemia is a _____ blood supply to an area of tissue, resulting in tissue _____
Definition
deficient, hypoxia
Term
Injury is a degree of tissue ______ that is severe enough to cause ______ to cells. Cells may/may not survive is perfusion is rapidly achieved.
Definition
hypoxia, damage, may
Term
Infarction is a degree of tissue ______ severe enough to cause reversible/irreversible ______ to cells. Reperfusion is/is not beneficial in this case.
Definition
hypoxia, irreversible, damage, is not
Term
An MI is a _______ or ______ development within the _____ as a result of minimal/severe deprivation of blood supply.
Definition
gangrenous, necrotic, myocardium, severe
Term
The evolution of an infarction is a result of 3 stages. Stage I is ______, Stage II is ______ and Stage III is ______
Definition
Injury, Infarction, Resolution
Term
_____ manifests within minutes to hours after the onset of ischemia and will persist until the cells either ____ or are ______.
Definition
Injury, die, reperfused
Term
Manifestations of myocardial death occur within ___ to ____ hours. Infarcted cells turn into ______ tissue and are/are not excitable.
Definition
24-48, scar, are not
Term
Necrotic tissue acts as a ____ conductor of action potentials generated from the viable ______ wall of the heart.
Definition
passive, opposite
Term
In an anterior infarction noted in ____ and ____ leads, the main vector will shift and point towards the _____ wall of the heart.
Definition
V3, V4, posterior
Term
Stage III is AKA ______ and occurs over ____ to ____ as the damaged tissue is replaced by _____ tissue.
Definition
Resolution, weeks, months, scar
Term
In general, a pt may have a ____ hour time frame to reperfuse before necrosis sets in.
Definition
6
Term
The "classic triad" of a transmural MI is:_____, ______ and ______.
Definition
ST elevation, pathological Q waves and T wave inversion
Term
What is the only immediate indicator of occlusion?
Definition
ST elevation
Term
T/F you need all 3 indicators in the triad to have an MI.
Definition
False, may or may not have Q waves, ST elevation or T wave changes.
Term
ST elevation signifies injury to tissue (significant hypoxia), and is most common during ____ and ____ of anesthesia.
Definition
induction, emergence
Term
ST elevation signifies a change in depolarization/repolarization.
Definition
Repolarization
Term
Pathological Q waves occur ____ to ____ after an infarction or may never occur. These types of Q waves signify a change in depolarization/repolarization.
Definition
hours, days, depolarization
Term
T wave inversion signifies a change in depolarization/repolarization and occurs _____ to ____ hours after an infarction. In other words, T wave changes occur early/late in the infarction process.
Definition
depolarization, 6-24, late
Term
Anterior MI: The _____ coronary artery supplies this region.
Definition
LAD
Term
Indicative leads in an anterior MI
Definition
V1-V4
Term
Reciprocal leads for ant MI
Definition
inferior (II, III, avF)
Term
Coronary artery blockage corresponding to an inferior MI
Definition
RCA
Term
Indicative leads for an inferior MI
Definition
II, III, avF
Term
Reciprocal leads for an inferior MI
Definition
anterior (V1-V4), Lateral (V5-V6)
Term
Coronary artery blockage corresponding to a lateral MI.
Definition
LCA
Term
Indicative leads for a lateral MI
Definition
I, aVL, V5, V6
Term
Reciprocal leads for a lateral MI.
Definition
Inferior (II, III, aVF)
Term
Coronary artery blockage corresponding to a posterior MI
Definition
RCA OR LCA
Term
Indicative leads for a posterior MI
Definition
V1 and V2 have tall R waves and depressed ST segment. We do not have direct indicative leads for a posterior MI, so we look for reciprocal changes.
Term
Reciprocal leads for a posterior MI
Definition
Anterior (V1-V4)
Term
ST elevation denotes myocardial ______.
Definition
injury
Term
Pathological Q waves denote myocardial _______
Definition
infarction
Term
T wave inversion denotes myocardial _______
Definition
ischemia
Term
T/F some people normally have some ST elevation.
Definition
True
Term
T/F It is common to have small Q waves in the inferior (II, III, aVF) and lateral (I, aVL, V5-V6) leads.
Definition
True, but note, they are small Q waves, not pathological.
Term
Pathological Q waves are ___ in duration and are ____ the height of the R wave
Definition
0.04 sec, 1/3
Term
T waves invert as the ST segment begins to ______, and occurs early/later in the MI process.
Definition
return to baseline, later
Term
T/F with an inferior MI, it is appropriate to look at the precordial leads as indicative leads.
Definition
False, with an inferior MI, you will see indicative changes in II, III, and aVF
Term
A lateral infarction corresponds to the _____ coronary artery.
Definition
L circ
Term
A septal infarction corresponds to a blockage in the _____ coronary artery and is indicated in _____ and _____ leads.
Definition
LAD, V1-V2
Term
With an inferior MI, you will probably see pathological Q waves in the inferior leads because the vectors are moving toward/away the area of infarction.
Definition
away
Term
Electrical impulses do/do not flow through the area of injury.
Definition
Do. This denotes the ST changes.
Term
With a transmural MI, there is more damage to the epicardial/endocardial surface.
Definition
endocardial.
Term
T/F you will see Q waves over leads other than the areas of infarction.
Definition
False.
Term
The following four conditions may also have associated ST elevation, related to CAD: Recent_____, Old _____ (aneurism), chronic ________, and _______ angina. These may all induce a sub-epicardial/endocardial MI.
Definition
MI, MI, coronary insufficiency, Prinzmetal's, subendocardial
Term
The following 8 conditions can lead to ST elevation that is not related to CAD: ____carditis, ______carditis, metabolic _______, intoxication, infectious diseases, endocrine D/O, acute ventricular overload AKA _________, _______ heart disease. These can all lead to a sub-epicardial/endocardial MI.
Definition
myo, peri, abnormalities, pulmonary embolism, congenital, subepicardial
Term
T/F The current of injury tends to resolve over time.
Definition
T. The ST segment normally returns to baseline.
Term
A good/poor prognosis is associated with 2nd and 3rd degree HB s/p Ant MI.
Definition
Poor
Term
Usually, like to see changes in _____ contiguous leads to denote infarction.
Definition
2
Term
An inferior MI is caused by occlusion of the ______, and can cause RV/LV infarction, as well as R/L axis deviation. Complications include heart blocks and brady/tachyarryhthmias.
Definition
RCA, RV, Left axis deviation, brady. The AVN is supplied by the RCA.
Term
If you see an EKG with a pathological Q wave and T wave inversion, how old is it?
Definition
Unable to determine...long enough for the ST segment to try to correct itself, but it may take hours to days.
Term
An anterior MI is caused by occlusion of the _____. It includes possible damage to the ____ and ____ resulting in _____ problems.
Definition
LAD, septum, bundle branches, conduction
Term
A lateral MI is caused by occlusion of the _____. There is a possible R/L axis deviation associated with this condition.
Definition
Left circumflex, right axis deviation. The left side is no longer conducting impulses, so these impulses are shifted to the right.
Term
A posterior MI can be caused by occlusion of either _____ or _____ and is associated with reciprocal changes in ____ and ____.
Definition
RCA, LCirc, V1, V2.
Term
What does an acute posterior MI look like?
Definition
ST depression in V1 and V2, tall R wave in V1-V2 or possibly V3.
Term
What does an old posterior MI look like?
Definition
Tall R waves in V1-V2, without ST changes
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