Term
| RA lower life expectancy by how many years? |
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Definition
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Term
| higher mortality rates with RA are ass with what/ |
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Definition
| peristant joint inflammation and seropositivity |
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Term
| what is the most common age of getting RA |
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Definition
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Term
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Definition
| hyperplastic synovial tissue ass with Ra |
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Term
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Definition
| cartilage, subchondral bone, articular capsule, and ligaments |
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Term
| which joit are most affected in RA |
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Definition
| PIPJ, MCP wrists elbows, knees |
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Term
| a FBE of RA patietn with slow what |
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Definition
| Normochromic normoctyic anaemia, increased ESR, +/- Fe deficiency, throbocytosis (high platelt level) |
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Term
| a diagonsis is made of RA by SAS Rx, what is this |
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Definition
| Stifness (am) >1hr, arthritis in 3+ areas, hands, symmetry, Rh factor, x ray features |
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Term
| RA would appear how on X-Ray |
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Definition
| soft tissue, swelling, juxta articular osteoporosis, decrease cartilage, erosions |
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Term
| Sjogrens syndrome is waht |
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Definition
| a chronic inflammatory disorder of unknown cause, leading to dry mucous membrane (eye mouth) |
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Term
| suffers of Sjogrens syndrome will have dessication nfo what |
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Definition
| skin, nose, throat, bronchi, vagina |
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Term
| what percentage of RA patients are Rh +ve |
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Definition
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Term
| Spondyloarthopathies are rh positive or negative |
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Definition
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Term
| what are the main musculoskeletal features of spondyloarthropathies? |
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Definition
| enthesopathy, synovitis, dactylitis, sacroilitis, spondylytis |
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Term
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Definition
| inflammation at insertion site of ligs, tendons, muscles into bone, which may lead to calcification |
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Term
which parts are false?
Spondyloarthropathies will generally have symmetrical, synovitis which is identical to RA on microscopy. and no sacroilitis |
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Definition
| can often be asymetrical, and does have sacrilitis |
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Term
| the spondylitis seen in spondyloarthopathies is becasue of what? |
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Definition
| synovitis at zygapophyseal joints, and enthesopathy of insertion of annulus fibrosis |
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Term
| what extra articular features of spondyloarthropathies are seen |
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Definition
| eyes (iritis)(not dry eyes), skin (psoriasis, and rashes), bowel (UC crohns), GIT |
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Term
| HLA b27 is present in how many of population? and how many of people with ankylosing spondylitis? |
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Definition
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Term
| what is seen on xray that is central to diagnosis of sacroilitis spondyloarthropathies |
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Definition
| narrowing of SI joints with irregular margins, sclerosis of periarticular bone and ultimately joint fusion |
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Term
| what does spondylitis involve/ |
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Definition
| squaring of vertebrae, development of syndesmophyts, apophyseal joint fusion, and bamboo spine |
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Term
| which joints rarely show inflammation in ankylosing spondylitits |
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Definition
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Term
| enthesopathy in akylosing spondylitis is seen where |
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Definition
| thigh adductors to pelvis (groin pain, ischial tuberosities, pelvic brim)achilles, plantar fascitis |
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Term
| HLA b27 is found in what percentage of people with ankylosing spondylitis |
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Definition
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Term
| what is the ration M:F in ankylosing spondylitis |
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Definition
|
|
Term
| what xray features are seen in ankylosing spondylitis |
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Definition
| sacoiliac joints - widen narrow, vertebral squaring, syndesmophytes, bamboo spine |
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Term
| Reactive arthritis is characterised by what? |
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Definition
| infection is the gut or sexually acquired genitourianry infection, folllowed 1-4 weeks later by sterile synovitis +/- extra articul involvement of skin eys or urinary tract |
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Term
| what cauda equina syndrome |
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Definition
| impotence, incontinence, decreased bladder/rectal sensation, absent ankle jerk reflex |
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Term
| what are 2 secondary causes of Ca pyrophosphate disease |
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Definition
| myxoderma (hypothyroidism), hyperparathyroidism, haemochromatosis |
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Term
| what are the differences of microscopy examination of synovial fluid, taken from people with gout and cap pyrophosphate disease |
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Definition
| CPPD is birefringent positive, gout is negative |
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Term
| ehlos danlos sydrom causes what foot deformity, what % of people with EDS have this condition |
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Definition
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Term
what is wrog with this statement?
marfans is an inherited connective tissue disorder that is autosomal recessive, with an 1 in 10000 incidence. the abnormalility is in the collagen gene. pts will show taller than average height, short digits, pes cavus and genu recurvatum |
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Definition
| autosomal dominant, abnormaility in fibillin gene, pes cauvs, long finger |
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Term
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Definition
| idiopathic avascular necrosis of upper femoral epiphysis |
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Term
| who does perthe's disease usualy affect |
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Definition
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Term
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Definition
| osteochondritis of tibial tubercle in males 10-15 yrs |
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Term
| scheurmanns disease is what |
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Definition
| osteochondritis of upper and lower cartilage endplates of IV disks |
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