Term
| Kleinhauer and Bekte (KB) test |
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Definition
| uses a 3.2 pH erythrosine B-hematoxylin stain to differentiate between adult (pale) and fetal (pink) RBC's |
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Term
| 3.3 pH citric acid-phosphate buffer |
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Definition
| used to bleach the related protein, while leaving unrelated proteins stained |
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Term
| fetal hemoglobin's higher affinity for O2 |
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Definition
| reason why the related protein migrates slower in alkaline electrophoresis |
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Term
| step 1 in hemoglobinometry |
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Definition
| potassium ferricyanide is added to oxidize the iron |
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|
Term
| step 2 in hemoglobinometry |
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Definition
| add potassium cyanide to add the cyano- group and make it readable spectrophometrically |
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Term
|
Definition
| cell-cell immune response |
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Term
|
Definition
| antibody-antigen immune response |
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Term
|
Definition
| involved in destruction of cells and foreign bodies using digestion enzymes |
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Term
|
Definition
| immune response involving antibodies, either directly or indirectly |
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Term
|
Definition
| heterozygous for the related gene, no serious adverse effects |
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Term
|
Definition
| homozyogous for related gene, adverse effects during related crisis |
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Term
|
Definition
| consumtion of non-food items |
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Term
|
Definition
| common cause of childhood pica |
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|
Term
|
Definition
| common cause of adult pica |
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Term
|
Definition
| deficient alpha chain production leading to short RBC lifespan, causing moderate anemia |
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Term
|
Definition
| lymphoma identified by polynuclear lymphocytes |
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Term
|
Definition
| abnormal build-up of of glychosphingolipids due to a deficiency in beta-glucosidase |
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Term
|
Definition
| occurs among ashkenazi jews, and patients live to adulthood |
|
|
Term
| type II gaucher's disease |
|
Definition
| develops w/in six months of birth, and die at 2-3 years |
|
|
Term
| type III gaucher's disease |
|
Definition
| chronic, patients live to be teenagers |
|
|
Term
| Chronic granulomatous disease (CGD) |
|
Definition
| phagocytes lack NADPH oxidase, rendering them unable to fight foreign bodies |
|
|
Term
| nitroblue tetrazolium test |
|
Definition
| used to determine the existence of CGD in a patient--reduced activity |
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Term
|
Definition
| overproduction of immature white blood cells in the marrow |
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Term
|
Definition
| overproduction of abnormal, yet mature white blood cells |
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Term
|
Definition
| white blood cells (often B-lymphocytes), exhibit the related phenotype, chronic |
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|
Term
| diagnosis of hairy cell leukemia |
|
Definition
| stained by acid phosphatase, not destained by tartaric acid |
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Term
|
Definition
| red blood cells are larger than normal on blood smear due to a folic acid deficiency |
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Term
|
Definition
| erythroblasts containing high amount of ferritin, resulting in a decreased ability to bind total iron |
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Term
|
Definition
| reduced production of RBCs, WBCs, and platelets: resulting in chronic infection, and prolonged PT/PTT. Diagnosed through bone marrow biopsy |
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|
Term
| relative anemia of pregnancy |
|
Definition
| mild condition effecting expectant mothers due to the doubling of their plasma |
|
|
Term
| 4.2-5.0 million/microliter |
|
Definition
| RBC count of a non-pregnant adult female |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| 150,000-400,000/microliter |
|
Definition
| platelet count of an npaf |
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Term
|
Definition
| neutrophil portion of the wbc's in an npaf |
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Term
|
Definition
| eosinophil portion of an npaf's wbc's |
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|
Term
|
Definition
| basophil portion of an npaf's wbc's |
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|
Term
|
Definition
| lymphocyte portion of an npaf's wbc's |
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|
Term
|
Definition
| monocyte portion of an npaf's wbc's |
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|
Term
|
Definition
| band portion of an npaf's wbc's |
|
|
Term
|
Definition
| Mean cell volume (MCV) of an npaf |
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|
Term
|
Definition
| mean cell hemoglobin of an npaf |
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|
Term
|
Definition
| mean cell hemoglobin concentration (MCHC) of an npaf |
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|
Term
|
Definition
| red cell distribution width of an npaf |
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|
Term
|
Definition
|
|
Term
|
Definition
| related reagent is added to patient RBCs, which will agglutinate if they're being hemolyzed by the immune system |
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Term
|
Definition
| washed RBCs are mixed with a test serum so that the antibodies therein bind to the washed RBCs. The related reagent is then added to mark the agglutination defining the degree of attachment |
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Term
|
Definition
| determines the presense of Heinz bodies in RBCs |
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|
Term
|
Definition
| iron detection in marrow, peripheral blood, or urine |
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