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Movement Disorders
Test 3
19
Pharmacology
Professional
03/23/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Trihexylphenidryl
Definition
Anti-cholinergic used to compensate for lack of Dopamine inhibition. Treats tremor in mild, early Parkinson's
Term
Benztropine
Definition
Anti-cholinergic used to compensate for lack of Dopamine inhibition. Treats tremor in mild, early Parkinson's
Term
Amantadine
Definition

Promotes Dopamine release, inhibits reuptake, anti-Ach, Glu receptor antagonist

*neuroprotective

Sfx: livedo reticularis

Term
Selegiline
Definition

MAO-B inhibitor (inhib dopamine breakdown)

*produces amphetamine-like metab

Do not get wine & cheese syndrome

Term
Baclofen
Definition

GABAA agonist for Dystonia

abruptly stopping can cause seizures

Term
Rasagiline
Definition

MAO-B inhibitor (inhib dopamine breakdown)

*produces amphetamine-like metab

Do not get wine & cheese syndrome

Term
Bromocriptine
Definition

Ergot-derived Dopamine Agonist

Sfx: retroperitoneal fibrosis

Term
Pramipexole
Definition

Non-ergot dopamine agonist

Sfx: Sleep attacks and compulsive behaviors

Term
Ropinirole
Definition

Non-ergot dopamine agonist

Sfx: Sleep attacks and compulsive behaviors

Term
Carbidopa
Definition
peripheral dopa-decarboxylase inhibitor
Term
Levidopa
Definition

Centrally converted to dopamine, most effective and rapidly acting treatment for IPD

*used with carbidopa and entacapone

Term
Entacapone
Definition

Peripherally acting COMT inhibitor (for levidopa)

*turns urine orange

Term
Apomorphine
Definition
"Rescue treatment" for episodes of severe symptoms of IPD
Term
Propranolol
Definition
Tx of essential tremor
Term
Primidone
Definition
Tx of essential tremor
Term
Gabapentin
Definition
Tx of essential tremor
Term
Alprazolam
Definition
Tx of essential tremor
Term
Clonazepam
Definition
Tx of essential tremor
Term
Botulinum Toxin
Definition
Tx of focal dystonias
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